Resultados da pesquisa - Benito Muñoz

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  1. 1
    Organotypic Cultures as a Model to Study Adult Neurogenesis in CNS Disorders

    Organotypic Cultures as a Model to Study Adult Neurogenesis in CNS Disorders Por Cavaliere, Fabio, Benito-Muñoz, Monica, Matute, Carlos

    Publicado em 2016
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  2. 2
    NMDA modulates oligodendrocyte differentiation of subventricular zone cells through PKC activation

    NMDA modulates oligodendrocyte differentiation of subventricular zone cells through PKC activation Por Cavaliere, Fabio, Benito-Muñoz, Monica, Panicker, Mitradas, Matute, Carlos

    Publicado em 2013
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  3. 3
    Author Correction: Assessing the effect of wind farms in fauna with a mathematical model

    Author Correction: Assessing the effect of wind farms in fauna with a mathematical model Por Román, Pablo Refoyo, Salinas, Cristina Olmedo, Araújo, Benito Muñoz

    Publicado em 2021
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  4. 4
    Structural Determinants of the Neuronal Glycine Transporter 2 for the Selective Inhibitors ALX1393 and ORG25543

    Structural Determinants of the Neuronal Glycine Transporter 2 for the Selective Inhibitors ALX1393 and ORG25543 Por Benito-Muñoz, Cristina, Perona, Almudena, Felipe, Raquel, Pérez-Siles, Gonzalo, Núñez, Enrique, Aragón, Carmen, López-Corcuera, Beatriz

    Publicado em 2021
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  5. 5
    Modification of a Putative Third Sodium Site in the Glycine Transporter GlyT2 Influences the Chloride Dependence of Substrate Transport

    Modification of a Putative Third Sodium Site in the Glycine Transporter GlyT2 Influences the Chloride Dependence of Substrate Transport Por Benito-Muñoz, Cristina, Perona, Almudena, Abia, David, dos Santos, Helena G., Núñez, Enrique, Aragón, Carmen, López-Corcuera, Beatriz

    Publicado em 2018
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  6. 6
    Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia

    Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia Por Timothy A. Lewis, David B. Sykes, Jason M. Law, Benito Muñoz, Joane K. Rustiguel, Maria Cristina Nonato, David T. Scadden, Stuart L. Schreiber

    Publicado em 2016
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  7. 7
    Development of small-molecule probes that selectively kill cells induced to express mutant RAS

    Development of small-molecule probes that selectively kill cells induced to express mutant RAS Por Michel Weïwer, Joshua A. Bittker, Timothy A. Lewis, Kaoru Shimada, Wan Seok Yang, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Brent R. Stockwell, Stuart L. Schreiber, Benito Muñoz

    Publicado em 2011
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  8. 8
    A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

    A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells Por Michel Weïwer, James Spoonamore, Jingqiang Wei, Boris Guichard, Nathan T. Ross, Kristina Masson, Whitney Silkworth, Sivaraman Dandapani, Michelle Palmer, Christina Scherer, Andrew M. Stern, Stuart L. Schreiber, Benito Muñoz

    Publicado em 2012
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  9. 9
    Use of a High-Throughput Phenotypic Screening Strategy to Identify Amplifiers, a Novel Pharmacological Class of Small Molecules That Exhibit Functional Synergy with Potentiators and Correctors

    Use of a High-Throughput Phenotypic Screening Strategy to Identify Amplifiers, a Novel Pharmacological Class of Small Molecules That Exhibit Functional Synergy with Potentiators an... Por Kenneth A. Giuliano, Shinichiro Wachi, Lawrence Drew, Danijela Dukovski, Olivia Green, Cecilia Bastos, Matthew D. Cullen, Sheila I. Hauck, Bradley D. Tait, Benito Muñoz, Po‐Shun Lee, John P. Miller

    Publicado em 2017
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  10. 10
    Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA

    Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA Por Danijela Dukovski, Adriana Villella, Cecilia Bastos, Randall W. King, Daniel Finley, Jeffery W. Kelly, Richard I. Morimoto, F. Ulrich Hartl, Benito Muñoz, Po-Shun Lee, Marija Zecevic, John P. Miller

    Publicado em 2020
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  11. 11
    Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

    Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction Por Longqin Hu, Sadagopan Magesh, Lin Chen, Lili Wang, Timothy A. Lewis, Yu Chen, Carol Khodier, Daigo Inoyama, Lesa J. Beamer, Thomas J. Emge, Jian Shen, John E. Kerrigan, Ah‐Ng Tony Kong, Sivaraman Dandapani, Michelle Palmer, Stuart L. Schreiber, Benito Muñoz

    Publicado em 2013
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  12. 12
    Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics

    Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics Por Luc de Waal, Timothy A. Lewis, Matthew G. Rees, Aviad Tsherniak, Xiaoyun Wu, Peter S. Choi, Lara Gechijian, Christina R. Hartigan, Patrick W. Faloon, Mark J. Hickey, Nicola Tolliday, Steven A. Carr, Paul A. Clemons, Benito Muñoz, Bridget K. Wagner, Alykhan F. Shamji, Angela N. Koehler, Monica Schenone, Alex B. Burgin, Stuart L. Schreiber, Heidi Greulich, Matthew Meyerson

    Publicado em 2015
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  13. 13
    Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset

    Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset Por Brinton Seashore‐Ludlow, Matthew G. Rees, Jaime H. Cheah, Murat Cokol, Edmund V. Price, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Joshua Gould, Benjamin Alexander, Ava Li, Philip Montgomery, Mathias J. Wawer, Nurdan Kuru, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Joshua A. Bittker, Michelle Palmer, James E. Bradner, Alykhan F. Shamji, Paul A. Clemons, Stuart L. Schreiber

    Publicado em 2015
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  14. 14
    Correlating chemical sensitivity and basal gene expression reveals mechanism of action

    Correlating chemical sensitivity and basal gene expression reveals mechanism of action Por Matthew G. Rees, Brinton Seashore‐Ludlow, Jaime H. Cheah, Drew Adams, Edmund V. Price, Shubhroz Gill, Sarah Javaid, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Benjamin Alexander, Ava Li, Philip Montgomery, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Daniel A. Haber, Clary B. Clish, Joshua A. Bittker, Michelle Palmer, Bridget K. Wagner, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber

    Publicado em 2015
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  15. 15
    Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

    Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria Por Richard W. Heidebrecht, Carol A. Mulrooney, Christopher P. Austin, Robert H. Barker, Jennifer A. Beaudoin, Ken Cheng, Eamon Comer, Sivaraman Dandapani, Justin Dick, Jeremy R. Duvall, Eric H. Ekland, David A. Fidock, Mark E. Fitzgerald, Michael A. Foley, Rajarshi Guha, Paul Hinkson, Martin Kramer, Amanda K. Lukens, Daniela Masi, Lisa A. Marcaurelle, Xin‐zhuan Su, Craig J. Thomas, Michel Weïwer, Roger C. Wiegand, Dyann F. Wirth, Menghang Xia, Jing Yuan, Jinghua Zhao, Michelle Palmer, Benito Muñoz, Stuart L. Schreiber

    Publicado em 2011
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  16. 16
    An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

    An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules Por Amrita Basu, Nicole E. Bodycombe, Jaime H. Cheah, Edmund V. Price, Ke Liu, Giannina I. Schaefer, Richard Y. Ebright, Michelle L. Stewart, Daisuke Ito, Stephanie Wang, Abigail Bracha, Ted Liefeld, Mathias J. Wawer, Joshua C. Gilbert, Andrew J. Wilson, Nicolas Stransky, Gregory V. Kryukov, Vlado Dančík, Jordi Barretina, Levi A. Garraway, C. Suk-Yee Hon, Benito Muñoz, Joshua A. Bittker, Brent R. Stockwell, Dineo Khabele, Andrew M. Stern, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber

    Publicado em 2013
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  17. 17
    Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model*

    Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model* Por Michael L. Booker, Cecilia M. Bastos, Martin Kramer, Robert H. Barker, Renato T. Skerlj, Amar Bir Singh Sidhu, Xiaoyi Deng, Cassandra A. Celatka, Joseph F. Cortese, Jose E. Guerrero Bravo, Keila N. Crespo Llado, Adelfa E. Serrano, Íñigo Angulo‐Barturen, Marı́a Belén Jiménez-Dı́az, Sara Viera, Helen Garuti, Sergio Wittlin, Petros Papastogiannidis, Jingwen Lin, Chris J. Janse, Shahid M. Khan, Manoj T. Duraisingh, Bradley I. Coleman, Elizabeth J. Goldsmith, Margaret A. Phillips, Benito Muñoz, Dyann F. Wirth, Jeffrey D. Klinger, Roger C. Wiegand, Edmund J. Sybertz

    Publicado em 2010
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  18. 18
    Towards patient-based cancer therapeutics

    Towards patient-based cancer therapeutics Por Stuart L. Schreiber, Alykhan F. Shamji, Paul A. Clemons, Cindy Hon, Angela N. Koehler, Benito Muñoz, Michelle Palmer, Andrew M. Stern, Bridget K. Wagner, Scott Powers, Scott W. Lowe, Xuecui Guo, A. Krasnitz, Eric T. Sawey, Raffaella Sordella, Lincoln Stein, Lloyd C. Trotman, Andrea Califano, Riccardo Dalla‐Favera, Adolfo A. Ferrando, Antonio Iavarone, Laura Pasqualucci, José Silva, Brent R. Stockwell, William C. Hahn, Lynda Chin, Ronald A. DePinho, Jesse S. Boehm, Shuba Gopal, Alan Huang, David E. Root, Barbara A. Weir, Daniela S. Gerhard, Jean C. Zenklusen, Michael G. Roth, Michael A. White, John D. Minna, John B. MacMillan, Bruce A. Posner

    Publicado em 2010
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  19. 19
    Niche-based screening identifies small-molecule inhibitors of leukemia stem cells

    Niche-based screening identifies small-molecule inhibitors of leukemia stem cells Por Kimberly A. Hartwell, Peter G. Miller, Siddhartha Mukherjee, Alissa R. Kahn, Alison L. Stewart, David J. Logan, Joseph Negri, Mildred Duvet, Marcus Järås, Rishi V. Puram, Vlado Dančík, Fátima Al‐Shahrour, Thomas Kindler, Zuzana Tóthová, Shrikanta Chattopadhyay, Thomas P. Hasaka, Rajiv Narayan, Mingji Dai, Christina Huang, Sebastian Shterental, Lisa P. Chu, J. Erika Haydu, Jae Hung Shieh, David P. Steensma, Benito Muñoz, Joshua A. Bittker, Alykhan F. Shamji, Paul A. Clemons, Nicola Tolliday, Anne E. Carpenter, D. Gary Gilliland, Andrew M. Stern, Malcolm A.S. Moore, David T. Scadden, Stuart L. Schreiber, Benjamin L. Ebert, Todd R. Golub

    Publicado em 2013
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  20. 20
    Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

    Diversity-oriented synthesis yields novel multistage antimalarial inhibitors Por Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato, Arvind Sharma, Manmohan Sharma, Micah Maetani, Jessica Bastien, Nicolas M. B. Brancucci, Joshua A. Bittker, Victoria Corey, David C. Clarke, Emily R. Derbyshire, Gillian L. Dornan, Sandra Duffy, Sean Eckley, Maurice A. Itoe, Karin M. J. Koolen, Timothy A. Lewis, Ping S. Lui, Amanda K. Lukens, Emily Lund, Sandra March, Elamaran Meibalan, Bennett C. Meier, Jacob A. McPhail, Branko Mitasev, Eli L. Moss, Morgane Sayes, Yvonne Van Gessel, Mathias J. Wawer, Takashi Yoshinaga, Anne‐Marie Zeeman, Vicky M. Avery, Sangeeta N. Bhatia, John E. Burke, Flaminia Catteruccia, Jon Clardy, Paul A. Clemons, Koen J. Dechering, Jeremy R. Duvall, Michael A. Foley, Fabian Gusovsky, Clemens H. M. Kocken, Matthias Marti, Marshall Morningstar, Benito Muñoz, Daniel E. Neafsey, Amit Sharma, Elizabeth A. Winzeler, Dyann F. Wirth, Christina Scherer, Stuart L. Schreiber

    Publicado em 2016
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