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Molecular characteristics of colorectal neuroendocrine carcinoma; similarities with adenocarcinoma rather than neuroendocrine tumor 由 Nobuyoshi Takizawa, Yoshihiro Ohishi, Minako Hirahashi, Shunsuke Takahashi, Kazuhiko Nakamura, Masao Tanaka, Eiji Oki, Ryoichi Takayanagi, Yoshinao Oda

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Treatment Rationale and Study Design for the JUNIPER Study: A Randomized Phase III Study of Abemaciclib With Best Supportive Care Versus Erlotinib With Best Supportive Care in Pati... 由 Jonathan W. Goldman, Peipei Shi, Martin Reck, Luis Paz‐Ares, Andrew Koustenis, Karla Hurt

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Somatic Mutation Spectrum of Non–Small-Cell Lung Cancer in African Americans: A Pooled Analysis 由 Luiz H. Araujo, Philip E. Lammers, Velmalia Matthews-Smith, Rosana Eisenberg, Adriana González, Ann G. Schwartz, Cynthia Timmers, Konstantin Shilo, Weiqiang Zhao, Thanemozhi G. Natarajan, Jianying Zhang, Ayse Selen Yilmaz, Tom Liu, Kevin R. Coombes, David P. Carbone

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Clinicopathologic Characteristics of the EGFR Gene Mutation in Non–small Cell Lung Cancer 由 Anne S. Tsao, Xi Tang, Bradley S. Sabloff, Lianchun Xiao, Hisayuki Shigematsu, Jack A. Roth, Margaret R. Spitz, Waun Ki Hong, Adi F. Gazdar, Ignacio I. Wistuba

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SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression 由 Ritika Tiwari, Swaroop Kumar Pandey, Sakshi Goel, Vipul Bhatia, Sudhanshu Shukla, Xiaojun Jing, Saravana M. Dhanasekaran, Bushra Ateeq

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Protein Tyrosine Phosphatases: Structure, Function, and Implication in Human Disease 由 Lutz Tautz, David Critton, Stefan Grotegut

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KRAS and BRAF Mutation Analysis in Routine Molecular Diagnostics 由 Daniëlle A.M. Heideman, Irene Lurkin, Marije Doeleman, Egbert F. Smit, Henk M.W. Verheul, Gerrit A. Meijer, Peter J.F. Snijders, Erik Thunnissen, Ellen C. Zwarthoff

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Targeted genomic profiling reveals recurrent KRAS mutations and gain of chromosome 1q in mesonephric carcinomas of the female genital tract 由 Jelena Mirković, Lynette M. Sholl, Elizabeth Garcia, Neal I. Lindeman, Laura E. MacConaill, Michelle S. Hirsch, Paola Dal Cin, Melissa Gorman, Justine A. Barletta, Marisa R. Nucci, W. Glenn McCluggage, Brooke E. Howitt

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Genomic landscape of salivary gland tumors 由 Shumei Kato, Sheryl K. Elkin, Maria Schwaederlé, Brett N. Tomson, Teresa Helsten, Jennifer Carter, Razelle Kurzrock

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Sensitivity of plasma BRAF^mutant and NRAS^mutant cell‐free DNA assays to detect metastatic melanoma in patients with low RECIST scores and non‐RECIST disease p... 由 Gregory Chang, Jyothirmayee S. Tadepalli, Yongzhao Shao, Yilong Zhang, Sarah A. Weiss, Eric M. Robinson, Cindy Spittle, Manohar R. Furtado, Dawne N. Shelton, George Karlin‐Neumann, Anna C. Pavlick, Iman Osman, David Polsky

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Improving the Limit of Detection for Sanger Sequencing: A Comparison of Methodologies for <i>KRAS</i> Variant Detection 由 C. Davidson, Emily Zeringer, Kristen J. Champion, Marie‐Pierre L. Gauthier, Fawn Wang, Jerry Boonyaratanakornkit, Julie R. Jones, Edgar Schreiber

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High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Met... 由 Halfdan Sørbye, Anca Dragomir, Magnus Sundström, Per Pfeiffer, Ulf Thunberg, Monica Bergfors, Kristine Aasebø, Geir Egil Eide, Fredrik Pontén, Camilla Qvortrup, Bengt Glimelius

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Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma 由 Christian Posch, Brian D. Cholewa, Igor Vujic, Martina Sanlorenzo, Jeffrey Ma, Sarasa T. Kim, Sonja Kleffel, Tobias Schatton, Klemens Rappersberger, Rosie Elizabeth Ann Gutteridge, Nihal Ahmad, Susana Ortiz‐Urda

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Precise Classification of Cervical Carcinomas Combined with Somatic Mutation Profiling Contributes to Predicting Disease Outcome 由 Vivian M. Spaans, Marjolijn D. Trietsch, Alexander A.W. Peters, Michelle Osse, Natalja T. ter Haar, Gert Jan Fleuren, Ekaterina S. Jordanova

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Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next‐generation sequencing assay 由 Yuri E. Nikiforov, Sally E. Carty, Simion I. Chiosea, Christopher J. Coyne, Umamaheswar Duvvuri, Robert L. Ferris, William E. Gooding, Steven P. Hodak, Shane O. LeBeau, N. Paul Ohori, Raja R. Seethala, Mitchell Tublin, Linwah Yip, Marina N. Nikiforova

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Analysis of TSC Cortical Tubers by Deep Sequencing of TSC1, TSC2 and KRAS Demonstrates that Small Second‐Hit Mutations in these Genes are Rare Events 由 Wei Qin, Jennifer A. Chan, Harry V. Vinters, Gary W. Mathern, David Neal Franz, Bruce E. Taillon, Pascal Bouffard, David J. Kwiatkowski

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Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases 由 Anna Melissa Schlitter, Kee‐Taek Jang, Günter Klöppel, Burcu Saka, Seung‐Mo Hong, Hye‐Jeong Choi, G. Johan A. Offerhaus, Ralph H. Hruban, Yoh Zen, Björn Konukiewitz, Ivonne Regel, Michael Allgäuer, Serdar Balcı, Olca Baştürk, Michelle D. Reid, Iréne Esposito, Volkan Adsay

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Role of ancillary studies in fine‐needle aspiration from selected tumors 由 Fernando Schmitt, Helena Barroca

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<i>In situ</i> mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics 由 Ida Grundberg, Sara Kiflemariam, Marco Mignardi, Juliana Imgenberg‐Kreuz, Karolina Edlund, Patrick Micke, Magnus Sundström, Tobias Sjöblom, Johan Botling, Mats Nilsson

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RAS mutations affect pattern of metastatic spread and increase propensity for brain metastasis in colorectal cancer 由 Rona Yaeger, Elizabeth P. Cowell, Joanne F. Chou, Alexandra N. Gewirtz, Laetitia Borsu, Efsevia Vakiani, David B. Solit, Neal Rosen, Marinela Capanu, Marc Ladanyi, Nancy E. Kemeny

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