نتائج البحث

High-throughput, quantitative analyses of genetic interactions in E. coli حسب Athanasios Typas, Robert J. Nichols, Deborah A. Siegele, Michael Shales, Sean R. Collins, Bentley Lim, Hannes Braberg, Natsuko Yamamoto, Rikiya Takeuchi, Barry L. Wanner, Hirotada Mori, Jonathan S. Weissman, Nevan J. Krogan, Carol A. Gross

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Analysis of Protein Stability and Ligand Interactions by Thermal Shift Assay حسب Kathy Huynh, Carrie L. Partch

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The evolving small‐molecule fluorescent‐conjugate toolbox for <scp>C</scp>lass <scp>A GPCRs</scp> حسب Andrea J. Vernall, Stephen J. Hill, Barrie Kellam

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An Improved Method for P2X7R Antagonist Screening حسب Rômulo José Soares‐Bezerra, Natiele Carla da Silva Ferreira, Anael Viana Pinto Alberto, André Gustavo Calvano Bonavita, Antônio Augusto Fidalgo-Neto, Andrea Surrage Calheiros, Válber da Silva Frutuoso, Luiz Anastácio Alves

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Imaging-Based High-Throughput Screening Assay To Identify New Molecules with Transmission-Blocking Potential against Plasmodium falciparum Female Gamete Formation حسب Celia Miguel-Blanco, Joël Lelièvre, Michael J. Delves, Ana I. Bardera, Jesús L. Presa, María José López-Barragán, Andrea Ruecker, Sara R. Marques, Robert E. Sinden, Esperanza Herreros

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Evaluating State Dependence and Subtype Selectivity of Calcium Channel Modulators in Automated Electrophysiology Assays حسب Yuri A. Kuryshev, Arthur Brown, Emir Duzic, Glenn E. Kirsch

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A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase حسب Damien Baud, Nadine Ladkau, Thomas S. Moody, John M. Ward, Helen C. Hailes

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Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs حسب Maire F. Osborn, Julia F. Alterman, Mehran Nikan, Hong Cao, Marie Cecile Didiot, Matthew Hassler, Andrew H. Coles, Anastasia Khvorova

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Reliable high-throughput screening with by limiting yeast cell death phenomena حسب Robert Weis, Ruud Luiten, Wolfgang Skranc, Helmut Schwab, M. Wubbolts, Anton Glieder

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An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies حسب Patricia A. Estep, Isabelle Caffry, Yao Yu, Tingwan Sun, Yuan Cao, Heather Lynaugh, Tushar Jain, Maximiliano Vásquez, Peter M. Tessier, Yingda Xu

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SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents حسب Yuzheng Zhao, Qingxun Hu, Feixiong Cheng, Ni Su, Aoxue Wang, Yejun Zou, Hanyang Hu, Xianjun Chen, Hai‐Meng Zhou, Xinzhi Huang, Kai Yang, Qian Zhu, Xue Wang, Jing Yi, Linyong Zhu, Xuhong Qian, Lixin Chen, Yun Tang, Joseph Loscalzo, Yi Yang

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Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase حسب Maya A. Farha, Tomasz L. Czarny, Cullen L. Myers, L.J. Worrall, Shawn French, Deborah G. Conrady, Yang Wang, Eric Oldfield, N.C.J. Strynadka, Eric D. Brown

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Screening for novel enzymes from metagenome and SIGEX, as a way to improve it حسب Jiae Yun, Sangryeol Ryu

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High‐throughput screening and small animal models, where are we? حسب Jean Giacomotto, Laurent Ségalat

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Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes حسب Melissa L. Sykes, Vicky M. Avery

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Static Biofilm Cultures of Gram‐Positive Pathogens Grown in a Microtiter Format Used for Anti‐Biofilm Drug Discovery حسب Steven M. Kwasny, Timothy J. Opperman

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High-throughput fluorescence imaging approaches for drug discovery using<i>in vitro</i>and<i>in vivo</i>three-dimensional models حسب Natalia J. Martinez, Steven A. Titus, Amanda K. Wagner, Anton Simeonov

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Enabling Lead Discovery for Histone Lysine Demethylases by High-Throughput RapidFire Mass Spectrometry حسب Sue Hutchinson, Melanie Leveridge, Michelle L. Heathcote, Peter Francis, Laura Williams, Michelle Gee, J. A. Muñoz, Bill Leavens, Anthony Shillings, Emma J. Jones, Paul Homes, Stuart M. Baddeley, Chun‐wa Chung, Angela Bridges, Argyrides Argyrou

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Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens حسب Christina Matheny, Michael C. Wei, Michael C. Bassik, Alicia J. Donnelly, Martin Kampmann, Masayuki Iwasaki, Obdulio Piloto, David E. Solow-Cordero, Donna M. Bouley, Rachel E. Rau, Patrick A. Brown, Michael T. McManus, Jonathan S. Weissman, Michael L. Cleary

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Fluorescence Polarization and Anisotropy in High Throughput Screening: Perspectives and Primer حسب John C. Owicki

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