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  1. 1
    Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer

    Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer by Adam R. Blanden, Xin Yu, Stewart N. Loh, Arnold J. Levine, Darren R. Carpizo

    Published 2015
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  2. 2
    Tunable and reversible drug control of protein production via a self-excising degron

    Tunable and reversible drug control of protein production via a self-excising degron by H. Kay Chung, C. Jacobs, Yunwen Huo, Jin Yang, Stefanie A. Krumm, Richard K. Plemper, Roger Y. Tsien, Michael Z. Lin

    Published 2015
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  3. 3
    Discovery, Structure–Activity Relationship, and Biological Evaluation of Noninhibitory Small Molecule Chaperones of Glucocerebrosidase

    Discovery, Structure–Activity Relationship, and Biological Evaluation of Noninhibitory Small Molecule Chaperones of Glucocerebrosidase by Samarjit Patnaik, Wei Zheng, Jae Hyuk Choi, Omid Motabar, Noel Southall, Wendy Westbroek, Wendy Lea, Arash Velayati, Ehud Goldin, Ellen Sidransky, William Leister, Juan Marugán

    Published 2012
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  4. 4
    Discovery of Novel Isatin-Based p53 Inducers

    Discovery of Novel Isatin-Based p53 Inducers by Pavel B. Davidovich, Vasilisa Aksenova, Varvara Petrova, Dmitri Tentler, D. D. Orlova, С. Н. Смирнов, Vladislav V. Gurzhiy, Andrei L. Okorokov, Aleksander Garabadzhiu, Gerry Melino, Н.А. Барлев, Vyacheslav G. Tribulovich

    Published 2015
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  5. 5
    Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE<sup>–/–</sup> Mice

    Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE<sup>–/–</sup> Mice by Azadeh Kheirolomoom, Chan Woo Kim, Jai Woong Seo, Sandeep Kumar, Dong Ju Son, Marie-Hélène Gagnon, Elizabeth S. Ingham, Katherine W. Ferrara, Hanjoong Jo

    Published 2015
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  6. 6
    Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1

    Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1 by An Hu, Jingjuan Huang, Ruilin Li, Zhao‐Yang Lu, Jun‐Li Duan, Weihua Xu, Xiaoping Chen, Jingping Fan

    Published 2015
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  7. 7
    Colloidal Aggregation Affects the Efficacy of Anticancer Drugs in Cell Culture

    Colloidal Aggregation Affects the Efficacy of Anticancer Drugs in Cell Culture by Shawn C. Owen, Allison K. Doak, Pascal Wassam, Molly S. Shoichet, Brian K. Shoichet

    Published 2012
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  8. 8
    Small molecule screening identifies targetable zebrafish pigmentation pathways

    Small molecule screening identifies targetable zebrafish pigmentation pathways by Sarah Colanesi, Kerrie L. Taylor, Nicholas D. Temperley, Pia R. Lundegaard, Dong Liu, Trista E. North, Hironori Ishizaki, Robert N. Kelsh, E. Elizabeth Patton

    Published 2012
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  9. 9
    At the Crossroads of Chemistry and Cell Biology: Inhibiting Membrane Traffic by Small Molecules

    At the Crossroads of Chemistry and Cell Biology: Inhibiting Membrane Traffic by Small Molecules by Lisa von Kleist, Volker Haucke

    Published 2011
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  10. 10
    Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors

    Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors by Kristin Beebe, Mehdi Mollapour, Bradley T. Scroggins, Chrisostomos Prodromou, Wanping Xu, Mari Tokita, Tony Taldone, Lester Pullen, Bettina K. Zierer, Min-Jung Lee, Jane B. Trepel, Johannes Büchner, Daniel N. Bolon, Gabriela Chiosis, Leonard Μ. Neckers

    Published 2013
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  11. 11
    Chapter 5 Applying the Genetics of Secondary Metabolism in Model Actinomycetes to the Discovery of New Antibiotics

    Chapter 5 Applying the Genetics of Secondary Metabolism in Model Actinomycetes to the Discovery of New Antibiotics by Gilles P. van Wezel, Nancy McKenzie, Justin R. Nodwell

    Published 2009
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  12. 12
    Small molecule tools for functional interrogation of protein tyrosine phosphatases

    Small molecule tools for functional interrogation of protein tyrosine phosphatases by Rongjun He, Li‐Fan Zeng, Yantao He, Sheng Zhang, Zhong‐Yin Zhang

    Published 2012
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  13. 13
    New dimension in therapeutic targeting of BCL-2 family proteins

    New dimension in therapeutic targeting of BCL-2 family proteins by Samaher Besbes, Massoud Mirshahi, Marc Pocard, Christian Billard

    Published 2015
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  14. 14
    The evolving small‐molecule fluorescent‐conjugate toolbox for <scp>C</scp>lass <scp>A GPCRs</scp>

    The evolving small‐molecule fluorescent‐conjugate toolbox for <scp>C</scp>lass <scp>A GPCRs</scp> by Andrea J. Vernall, Stephen J. Hill, Barrie Kellam

    Published 2013
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  15. 15
    Targeting disordered proteins with small molecules using entropy

    Targeting disordered proteins with small molecules using entropy by Gabriella T. Heller, Pietro Sormanni, Michele Vendruscolo

    Published 2015
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  16. 16
    Catalytic in vivo protein knockdown by small-molecule PROTACs

    Catalytic in vivo protein knockdown by small-molecule PROTACs by Daniel P. Bondeson, Alina Mares, Ian E. Smith, Eunhwa Ko, Sébastien Campos, Afjal H. Miah, Katie E Mulholland, Natasha Routly, Dennis L. Buckley, Jeffrey L. Gustafson, Nico Zinn, Paola Grandi, Satoko Shimamura, Giovanna Bergamini, Maria Faelth-Savitski, Marcus Bantscheff, Carly S. Cox, Deborah A. Gordon, Ryan R. Willard, John J. Flanagan, Linda Casillas, Bartholomew J. Votta, Willem den Besten, Kristoffer Famm, Laurens Kruidenier, Paul S. Carter, John D. Harling, Ian Churcher, Craig M. Crews

    Published 2015
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  17. 17
    Preclinical evaluation of a bispecific low‐molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer

    Preclinical evaluation of a bispecific low‐molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer by Matthias Eder, Martin Schäfer, Ulrike Bauder‐Wüst, Uwe Haberkorn, Michael Eisenhut, Klaus Kopka

    Published 2014
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  18. 18
    Twenty years of cell‐penetrating peptides: from molecular mechanisms to therapeutics

    Twenty years of cell‐penetrating peptides: from molecular mechanisms to therapeutics by F. Heitz, May C. Morris, Gilles Divita

    Published 2009
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  19. 19
    Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers

    Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers by Anthony L. Albiston, Shanti Diwakarla, Ruani Fernando, Simon J. Mountford, Holly R. Yeatman, Broden J. Morgan, Vi Pham, Jessica K. Holien, Michael W. Parker, Philip E. Thompson, Siew Yeen Chai

    Published 2011
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  20. 20
    Discovery and Development of Small Molecule SHIP Phosphatase Modulators

    Discovery and Development of Small Molecule SHIP Phosphatase Modulators by Dennis R. Viernes, Lydia B. Choi, William G. Kerr, John D. Chisholm

    Published 2013
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