Resultados de búsqueda - Tony Taldone

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  1. 1
    Purine-Scaffold Hsp90 Inhibitors

    Purine-Scaffold Hsp90 Inhibitors por Tony Taldone, Gabriela Chiosis

    Publicado 2009
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  2. 2
    Discovery and development of heat shock protein 90 inhibitors

    Discovery and development of heat shock protein 90 inhibitors por Tony Taldone, Weilin Sun, Gabriela Chiosis

    Publicado 2008
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  3. 3
    Targeting Hsp90: small-molecule inhibitors and their clinical development

    Targeting Hsp90: small-molecule inhibitors and their clinical development por Tony Taldone, Alexander Gozman, Ronnie Maharaj, Gabriela Chiosis

    Publicado 2008
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  4. 4
    Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers

    Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers por Komal Jhaveri, Tony Taldone, Shanu Modi, Gabriela Chiosis

    Publicado 2011
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  5. 5
    Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment

    Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment por Hardik Patel, Shanu Modi, Gabriela Chiosis, Tony Taldone

    Publicado 2011
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  6. 6
    Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

    Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease por Liza Shrestha, Alexander Bolaender, Hardik Patel, Tony Taldone

    Publicado 2016
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  7. 7
    Selective targeting of the stress chaperome as a therapeutic strategy

    Selective targeting of the stress chaperome as a therapeutic strategy por Tony Taldone, Stefan O. Ochiana, Pallav D. Patel, Gabriela Chiosis

    Publicado 2014
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  8. 8
    Heat shock protein 90 in neurodegenerative diseases

    Heat shock protein 90 in neurodegenerative diseases por Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis

    Publicado 2010
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  9. 9
    Synthesis of Reblastatin, Autolytimycin, and Non-Benzoquinone Analogues: Potent Inhibitors of Heat Shock Protein 90

    Synthesis of Reblastatin, Autolytimycin, and Non-Benzoquinone Analogues: Potent Inhibitors of Heat Shock Protein 90 por Iwona Wrona, Alexander Gozman, Tony Taldone, Gabriela Chiosis, James S. Panek

    Publicado 2010
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  10. 10
    Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab

    Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab por Jason P. Holland, Eloisi Caldas-Lopes, Vadim Divilov, Valerie A. Longo, Tony Taldone, Danuta Zatorska, Gabriela Chiosis, Jason S. Lewis

    Publicado 2010
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  11. 11
    Design, synthesis, and evaluation of small molecule Hsp90 probes

    Design, synthesis, and evaluation of small molecule Hsp90 probes por Tony Taldone, Danuta Zatorska, Pallav D. Patel, Hongliang Zong, Anna Rodina, James H. Ahn, Kamalika Moulick, Mónica L. Guzmán, Gabriela Chiosis

    Publicado 2011
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  12. 12
    Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

    Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series por Tony Taldone, Pallav D. Patel, Maulik Patel, Hardik J. Patel, Christopher E. B. Evans, Anna Rodina, Stefan O. Ochiana, Smit Shah, Mohammad Uddin, D.T. Gewirth, Gabriela Chiosis

    Publicado 2013
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  13. 13
    Pre‐clinical efficacy of PU‐H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

    Pre‐clinical efficacy of PU‐H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma por Srikanth R. Ambati, Eloisi Caldas Lopes, Kohji Kosugi, Ullas Mony, Ahmet Zehir, Smit Shah, Tony Taldone, André L. Moreira, Paul A. Meyers, Gabriela Chiosis, Malcolm A.S. Moore

    Publicado 2013
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  14. 14
    Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

    Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2 por Pallav D. Patel, Pengrong Yan, Paul M. Seidler, Hardik J. Patel, Weilin Sun, Chenghua Yang, Nanette S. Que, Tony Taldone, Paola Finotti, Ralph A. Stephani, D.T. Gewirth, Gabriela Chiosis

    Publicado 2013
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  15. 15
    Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

    Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70 por Yanlong Kang, Tony Taldone, Hardik J. Patel, Pallav D. Patel, Anna Rodina, Alexander Gozman, Ronnie Maharaj, Cristina C. Clement, Maulik Patel, Jeffrey L. Brodsky, Jason C. Young, Gabriela Chiosis

    Publicado 2014
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  16. 16
    Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

    Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an All... por Tony Taldone, Yanlong Kang, Hardik J. Patel, Maulik Patel, Pallav D. Patel, Anna Rodina, Yogita Patel, Alexander Gozman, Ronnie Maharaj, Cristina C. Clement, Alvin Lu, Jason C. Young, Gabriela Chiosis

    Publicado 2014
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  17. 17
    Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies

    Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies por Utthara Nayar, Pin Lü, Rebecca Goldstein, Jelena Vider, Gianna Ballon, Anna Rodina, Tony Taldone, Hediye Erdjument‐Bromage, Max Chomet, Ronald Blasberg, Ari Melnick, Leandro Cerchietti, Gabriela Chiosis, Y. Lynn Wang, Ethel Cesarman

    Publicado 2013
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  18. 18
    Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms

    Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms por Neha Bhagwat, Priya Koppikar, Matthew D. Keller, Sachie Marubayashi, Kaitlyn Shank, Raajit K. Rampal, Jun Qi, Maria Kleppe, Hardik J. Patel, Smit Shah, Tony Taldone, James E. Bradner, Gabriela Chiosis, Ross L. Levine

    Publicado 2014
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  19. 19
    Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation

    Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation por Sun Young Chung, Sarah Kishinevsky, Joseph R. Mazzulli, John J. Graziotto, Ana Mrejeru, Eugene V. Mosharov, Lesly Puspita, Parvin Valiulahi, David Sulzer, Teresa A. Milner, Tony Taldone, Dimitri Krainc, Lorenz Studer, Jae-won Shim

    Publicado 2016
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  20. 20
    Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors

    Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors por Kristin Beebe, Mehdi Mollapour, Bradley T. Scroggins, Chrisostomos Prodromou, Wanping Xu, Mari Tokita, Tony Taldone, Lester Pullen, Bettina K. Zierer, Min-Jung Lee, Jane B. Trepel, Johannes Büchner, Daniel N. Bolon, Gabriela Chiosis, Leonard Μ. Neckers

    Publicado 2013
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