Resultados da pesquisa

Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma Por Winnie Lo, Jay S. Wunder, Brendan C. Dickson, Veronica T. Campbell, Karen McGovern, Benjamin A. Alman, Irene L. Andrulis

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Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation Por Naz Chaudary, Melania Pintilie, David W. Hedley, Anthony Fyles, Michael Milosevic, Blaise Clarke, Rićhard P. Hill, Helen Mackay

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Non-Canonical Hh Signaling in Cancer—Current Understanding and Future Directions Por Dongsheng Gu, Jingwu Xie

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Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma Por Daniel D. Von Hoff, Patricia LoRusso, Charles M. Rudin, Josina C. Reddy, Robert L. Yauch, Raoul Tibes, Glen J. Weiss, Mitesh J. Borad, Christine L. Hann, Julie R. Brahmer, Howard Mackey, B. Lum, Walter C. Darbonne, James C. Marsters, Frédéric J. de Sauvage, Jennifer A. Low

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Basal Cell Carcinomas Arise from Hair Follicle Stem Cells in Ptch1+/− Mice Por Grace Wang, Joy Wang, Maria‐Laura Mancianti, Ervin H. Epstein

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Subtypes of medulloblastoma have distinct developmental origins Por Paul Gibson, Yiai Tong, Giles Robinson, Margaret C. Thompson, D. Spencer Currle, Christopher Eden, Tanya A. Kranenburg, Twala L. Hogg, Helen Poppleton, Julie Martin, David Finkelstein, Stanley Pounds, Aaron Weiss, Zoltán Patay, Matthew Scoggins, Robert J. Ogg, Yanxin Pei, Zeng-jie Yang, Sonja N. Brun, Youngsoo Lee, Frédérique Zindy, Janet C. Lindsey, Makoto M. Taketo, Frederick A. Boop, Robert A. Sanford, Amar Gajjar, Steven C. Clifford, Martine F. Roussel, Peter J. McKinnon, David H. Gutmann, David W. Ellison, Robert J. Wechsler‐Reya, Richard J. Gilbertson

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Hedgehog signaling pathway and gastric cancer Por Yuriko Katoh, Masaru Katoh

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Increased expression of sonic hedgehog and altered methylation of its promoter region in gastric cancer and its related lesions Por Lihui Wang, Yoon‐La Choi, Xuan-Yan Hua, Young Kee Shin, Young‐Jin Song, Sei-jin Youn, Hyo-Young Yun, Seon-Mee Park, Wun‐Jae Kim, Hee‐Jin Kim, Jong‐Sun Choi, Seok-Hyung Kim

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Spectrum of PTCH1 Mutations in French Patients with Gorlin Syndrome Por Nathalie Boutet, Yves‐Jean Bignon, Valérie Drouin‐Garraud, Pierre Sarda, Michel Longy, Didier Lacombe, Philippe Gorry

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Hedgehog signaling is activated in subsets of esophageal cancers Por Xiaoli Ma, Tao Sheng, Yuanxin Zhang, Xiaoli Zhang, Jing He, Shuhong Huang, Kai Chen, Josh Sultz, Patrick A. Adegboyega, Hongwei Zhang, Jingwu Xie

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Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception Por Shen Yue, Liu-Ya Tang, Ying Tang, Yi Tang, Qiuhong Shen, Jie Ding, Yan Chen, Zengdi Zhang, Tingting Yu, Ying E. Zhang, Steven Y. Cheng

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Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma Por Sabrina Pricl, Barbara Cortelazzi, Valentina Dal Col, Domenico Marson, Erik Laurini, Maurizio Fermeglia, Lisa Licitra, Silvana Pilotti, Paolo Bossi, Federica Perrone

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Pilot Clinical Trial of Hedgehog Pathway Inhibitor GDC-0449 (Vismodegib) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma Por Edward Kim, Vaibhav Sahai, Ethan V. Abel, Kent A. Griffith, Joel K. Greenson, Naoko Takebe, Gazala Khan, John Blau, Ronald A. Craig, Ulysses J. Balis, Mark M. Zalupski, Diane M. Simeone

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Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development Por Olena Zhulyn, Erica Nieuwenhuis, Yulu Cherry Liu, Stéphane Angers, Chi‐chung Hui

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Hedgehog signaling and response to cyclopamine differs in epithelial and stromal cells in benign breast and breast cancer Por Shibani Mukherjee, Natalya Frolova, Andrea Sadlonova, Zdeněk Novák, Adam D. Steg, Grier P. Page, Danny R. Welch, Susan M. Lobo-Ruppert, J. Michael Ruppert, Martin R. Johnson, Andra R. Frost

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A Five-Gene Hedgehog Signature Developed as a Patient Preselection Tool for Hedgehog Inhibitor Therapy in Medulloblastoma Por Yaping Shou, Douglas Robinson, Dereck D. Amakye, Kristine Rose, Yoon-Jae Cho, Keith L. Ligon, Thad Sharp, Asifa Haider, Raj Bandaru, Yukio Ando, Birgit Geoerger, François Doz, David M. Ashley, Darren Hargrave, Michela Casanova, Hussein Tawbi, Jordi Rodón, Anne Thomas, Alain C. Mita, Tobey J. MacDonald, Mark W. Kieran

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Gli1 is important for medulloblastoma formation in Ptc1+/− mice Por Hiromichi Kimura, Daniel Stephen, Alexandra L. Joyner, Tom Curran

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The dawn of hedgehog inhibitors: Vismodegib Por Sandhiya Selvarajan, George Melvin, Srinivasamurthy Suresh Kumar, Steven Aibor Dkhar

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<i>Sleeping Beauty</i> mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups Por Laura A. Genovesi, Ching Ging Ng, Melissa J. Davis, Marc Remke, Michael D. Taylor, David J. Adams, Alistair G. Rust, Jerrold M. Ward, Kenneth Ban, Nancy A. Jenkins, Neal G. Copeland, Brandon J. Wainwright

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Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling Por Hong Chang, Qing Li, Ricardo Moraes, Michael T. Lewis, Paul A. Hamel

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