Resultados da busca - Steven C. Clifford

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  1. 1
    Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease

    Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease por Steven C. Clifford

    Publicado em 2001
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  2. 2
    PDGFRB is overexpressed in metastatic medulloblastoma

    PDGFRB is overexpressed in metastatic medulloblastoma por Richard J. Gilbertson, Steven C. Clifford

    Publicado em 2003
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  3. 3
    TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours

    TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours por Janet C. Lindsey, Ed C. Schwalbe, Sandeep Potluri, Simon Bailey, Daniel Williamson, Steven C. Clifford

    Publicado em 2013
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  4. 4
    Combined Histopathological and Molecular Cytogenetic Stratification of Medulloblastoma Patients

    Combined Histopathological and Molecular Cytogenetic Stratification of Medulloblastoma Patients por Jayne M. Lamont, Charles S. McManamy, Andrew D.J. Pearson, Steven C. Clifford, David W. Ellison

    Publicado em 2004
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  5. 5
    Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma

    Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma por Janet C. Lindsey, M. Lusher, Jennifer Anderton, Richard J. Gilbertson, David W. Ellison, Steven C. Clifford

    Publicado em 2007
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  6. 6
    The pVHL-associated SCF ubiquitin ligase complex: Molecular genetic analysis of elongin B and C, Rbx1 and HIF-1α in renal cell carcinoma

    The pVHL-associated SCF ubiquitin ligase complex: Molecular genetic analysis of elongin B and C, Rbx1 and HIF-1α in renal cell carcinoma por Steven C. Clifford, Dewi Astuti, Laura C. Hooper, Patrick H. Maxwell, Peter J. Ratcliffe, Eamonn R. Maher

    Publicado em 2001
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  7. 7
    The clinical significance of sub-total surgical resection in childhood medulloblastoma: a multi-cohort analysis of 1100 patients

    The clinical significance of sub-total surgical resection in childhood medulloblastoma: a multi-cohort analysis of 1100 patients por Claire Keeling, Simon Davies, Jack Goddard, Vijay Ramaswamy, Ed C. Schwalbe, Simon Bailey, Debbie Hicks, Steven C. Clifford

    Publicado em 2024
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  8. 8
    Wnt/Wingless Pathway Activation and Chromosome 6 Loss Characterise a Distinct Molecular Sub-Group of Medulloblastomas Associated with a Favourable Prognosis

    Wnt/Wingless Pathway Activation and Chromosome 6 Loss Characterise a Distinct Molecular Sub-Group of Medulloblastomas Associated with a Favourable Prognosis por Steven C. Clifford, Meryl E. Lusher, Janet C. Lindsey, J Langdon, Richard J. Gilbertson, Debbie Straughton, David W. Ellison

    Publicado em 2006
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  9. 9
    Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2

    Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2 por Jennifer Anderton, Janet C. Lindsey, Meryl E. Lusher, Richard J. Gilbertson, Simon Bailey, David W. Ellison, Steven C. Clifford

    Publicado em 2008
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  10. 10
    Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial

    Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial por Simon Bailey, Nicolás André, Lorenza Gandola, Maura Massimino, Keith Wheatley, Simon Gates, Victoria Homer, Stefan Rutkowski, Steven C. Clifford

    Publicado em 2022
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  11. 11
    Morphophenotypic Variation Predicts Clinical Behavior in Childhood Non-Desmoplastic Medulloblastomas

    Morphophenotypic Variation Predicts Clinical Behavior in Childhood Non-Desmoplastic Medulloblastomas por Charles S. McManamy, Jayne M. Lamont, Roger Taylor, Michael Cole, Andrew D.J. Pearson, Steven C. Clifford, David W. Ellison

    Publicado em 2003
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  12. 12
    Amplification and Overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in Medulloblastoma

    Amplification and Overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in Medulloblastoma por Lu Yuan, Sarra L. Ryan, David J. Elliott, Graham R. Bignell, P. Andrew Futreal, David W. Ellison, Simon Bailey, Steven C. Clifford

    Publicado em 2009
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  13. 13
    Nodule Formation and Desmoplasia in Medulloblastomas—Defining the Nodular/Desmoplastic Variant and Its Biological Behavior

    Nodule Formation and Desmoplasia in Medulloblastomas—Defining the Nodular/Desmoplastic Variant and Its Biological Behavior por Charles S. McManamy, Jane Pears, Claire Weston, Zoltan Hanzely, James W. Ironside, Roger Taylor, Richard G. Grundy, Steven C. Clifford, David W. Ellison

    Publicado em 2007
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  14. 14
    Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling

    Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling por Janet C. Lindsey, Meryl E. Lusher, Jennifer Anderton, Simon Bailey, Richard J. Gilbertson, Andrew D.J. Pearson, David W. Ellison, Steven C. Clifford

    Publicado em 2003
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  15. 15
    Differences in Allelic Distribution of Two Polymorphisms in the VHL-Associated Gene<i>CUL2</i>in Pheochromocytoma Patients without Somatic<i>CUL2</i>Mutations<sup>1</sup>

    Differences in Allelic Distribution of Two Polymorphisms in the VHL-Associated Gene<i>CUL2</i>in Pheochromocytoma Patients without Somatic<i>CUL2</i>Mutations<sup>1</sup> por Eva-Maria Duerr, Oliver Gimm, Donna Neuberg, Jennifer B. Kum, Steven C. Clifford, S. P. A. Toledo, Eamonn R. Maher, Patricia L. M. Dahia, Charis Eng

    Publicado em 1999
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  16. 16
    Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial

    Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial por Tobias Goschzik, Ed C. Schwalbe, Debbie Hicks, Amanda Smith, Anja zur Muehlen, Dominique Figarella‐Branger, François Doz, Stefan Rutkowski, Birgitta Lannering, Torsten Pietsch, Steven C. Clifford

    Publicado em 2018
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  17. 17
    Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables

    Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables por David W. Ellison, Mehmet Koçak, James Dalton, Hisham Megahed, Meryl E. Lusher, Sarra L. Ryan, Wei Zhao, Sarah Leigh Nicholson, Roger Taylor, Simon Bailey, Steven C. Clifford

    Publicado em 2010
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  18. 18
    Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein

    Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein por Matthew E. Cockman, Norma Masson, David R. Mole, Panu Jaakkola, Gin-Wen Chang, Steven C. Clifford, Eamonn R. Maher, Christopher W. Pugh, Peter J. Ratcliffe, Patrick H. Maxwell

    Publicado em 2000
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  19. 19
    Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial

    Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial por Steven C. Clifford, Birgitta Lannering, Ed C. Schwalbe, Debbie Hicks, Kieran Toole, Sarah Leigh Nicholson, Tobias Goschzik, Anja zur Mühlen, Dominique Figarella‐Branger, François Doz, Stefan Rutkowski, Göran Gustafsson, Torsten Pietsch

    Publicado em 2015
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  20. 20
    Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly(ADP-ribose) polymerase inhibitor AG-014699

    Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly(ADP-ribose) polymerase inhibitor AG-014699 por Rachel Daniel, Agata Rozanska, Evan A. Mulligan, Yvette Drew, Huw D. Thomas, Deborah J. Castelbuono, Zdeněk Hostomský, Elizabeth Ruth Plummer, Deborah A. Tweddle, Alan V. Boddy, Steven C. Clifford, Nicola J. Curtin

    Publicado em 2010
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