Store-Operated Ca 2+ Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity
T follicular helper (Tfh) cells promote affinity maturation of B cells in germinal centers (GCs), whereas T follicular regulatory (Tfr) cells limit the GC reaction. Store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels mediated by STIM and ORAI proteins is a fundamenta...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2016
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| Online-Zugang: | https://doi.org/10.1016/j.immuni.2016.04.013 https://www.cell.com/article/S107476131630142X/pdf |
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