Store-Operated Ca 2+ Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity

T follicular helper (Tfh) cells promote affinity maturation of B cells in germinal centers (GCs), whereas T follicular regulatory (Tfr) cells limit the GC reaction. Store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels mediated by STIM and ORAI proteins is a fundamenta...

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Hlavní autoři: Martin Vaeth, Miriam Eckstein, Patrick J. Shaw, Lina Kozhaya, Jun J. Yang, Friederike Berberich‐Siebelt, Robert M. Clancy, Derya Unutmaz, Stefan Feske
Médium: Artigo
Jazyk:angličtina
Vydáno: 2016
On-line přístup:https://doi.org/10.1016/j.immuni.2016.04.013
https://www.cell.com/article/S107476131630142X/pdf
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