Risultati della ricerca - Yue‐Ming Li

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  1. 1
    The role of astrocytes in amyloid production and Alzheimer's disease

    The role of astrocytes in amyloid production and Alzheimer's disease di Georgia Frost, Yue‐Ming Li

    Pubblicazione 2017
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  2. 2
    Physiological and pathological roles of the γ-secretase complex

    Physiological and pathological roles of the γ-secretase complex di Courtney M. Carroll, Yue‐Ming Li

    Pubblicazione 2016
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  3. 3
    Turning the tide on Alzheimer’s disease: modulation of γ-secretase

    Turning the tide on Alzheimer’s disease: modulation of γ-secretase di Joanna E. Luo, Yue‐Ming Li

    Pubblicazione 2022
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  4. 4
    Isolation and Characterization of a Moderately Thermophilic Anaerobic Alkaliphile, Clostridium paradoxum sp. nov.

    Isolation and Characterization of a Moderately Thermophilic Anaerobic Alkaliphile, Clostridium paradoxum sp. nov. di Yue‐Ming Li, L. Mandelco, Juergen Wiegel

    Pubblicazione 1993
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  5. 5
    Complex regulation of γ-secretase: from obligatory to modulatory subunits

    Complex regulation of γ-secretase: from obligatory to modulatory subunits di Natalya Gertsik, Danica Chiu, Yue‐Ming Li

    Pubblicazione 2015
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  6. 6
    Gender- and Age-Dependent γ-Secretase Activity in Mouse Brain and Its Implication in Sporadic Alzheimer Disease

    Gender- and Age-Dependent γ-Secretase Activity in Mouse Brain and Its Implication in Sporadic Alzheimer Disease di Lisa Placanica, Lei Zhu, Yue‐Ming Li

    Pubblicazione 2009
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  7. 7
    Development and Mechanism of γ-Secretase Modulators for Alzheimer’s Disease

    Development and Mechanism of γ-Secretase Modulators for Alzheimer’s Disease di Christina J. Crump, Douglas S. Johnson, Yue‐Ming Li

    Pubblicazione 2013
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  8. 8
    Friend, Foe or Both? Immune Activity in Alzheimer’s Disease

    Friend, Foe or Both? Immune Activity in Alzheimer’s Disease di Georgia Frost, Lauren A. Jonas, Yue‐Ming Li

    Pubblicazione 2019
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  9. 9
    Processing of Notch and amyloid precursor protein by γ-secretase is spatially distinct

    Processing of Notch and amyloid precursor protein by γ-secretase is spatially distinct di Leonid Tarassishin, Ye Ingrid Yin, Bhramdeo Bassit, Yue‐Ming Li

    Pubblicazione 2004
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  10. 10
    Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain

    Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain di Xuenian Huang, Xuefeng Lü, Yue‐Ming Li, Xia Li, Jianjun Li

    Pubblicazione 2014
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  11. 11
    Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus

    Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus di Xuenian Huang, Mei Chen, Xuefeng Lü, Yue‐Ming Li, Xia Li, Jianjun Li

    Pubblicazione 2014
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  12. 12
    γ-Secretase Substrate Concentration Modulates the Aβ42/Aβ40 Ratio

    γ-Secretase Substrate Concentration Modulates the Aβ42/Aβ40 Ratio di Ye Ingrid Yin, Bhramdeo Bassit, Lei Zhu, Xia Yang, Chunyu Wang, Yue‐Ming Li

    Pubblicazione 2007
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  13. 13
    A Dimeric Smac/Diablo Peptide Directly Relieves Caspase-3 Inhibition by XIAP

    A Dimeric Smac/Diablo Peptide Directly Relieves Caspase-3 Inhibition by XIAP di Zhonghua Gao, Yuan Tian, Junru Wang, Qian Yin, Hao Wu, Yue Ming Li, Xuejun Jiang

    Pubblicazione 2007
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  14. 14
    Familial Alzheimer Disease Presenilin-1 Mutations Alter the Active Site Conformation of γ-secretase

    Familial Alzheimer Disease Presenilin-1 Mutations Alter the Active Site Conformation of γ-secretase di De-Ming Chau, Christina J. Crump, Jennifer C. Villa, David A. Scheinberg, Yue‐Ming Li

    Pubblicazione 2012
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  15. 15
    GSAP modulates γ-secretase specificity by inducing conformational change in PS1

    GSAP modulates γ-secretase specificity by inducing conformational change in PS1 di Eitan Wong, George P. Liao, Jerry C. Chang, Peng Xu, Yue‐Ming Li, Paul Greengard

    Pubblicazione 2019
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  16. 16
    Computer-Aided and AILDE Approaches to Design Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

    Computer-Aided and AILDE Approaches to Design Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors di Shi, Juan, Gao, Shuang, Wang, Jia-Yu, Ye, Tong, Yue, Ming-Li, Fu, Ying, Ye, Fei

    Pubblicazione 2022
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  17. 17
    Activation and intrinsic γ-secretase activity of presenilin 1

    Activation and intrinsic γ-secretase activity of presenilin 1 di Kwangwook Ahn, Christopher C. Shelton, Yuan Tian, Xulun Zhang, M. Lane Gilchrist, Sangram S. Sisodia, Yue‐Ming Li

    Pubblicazione 2010
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  18. 18
    Pen2 and Presenilin-1 Modulate the Dynamic Equilibrium of Presenilin-1 and Presenilin-2 γ-Secretase Complexes

    Pen2 and Presenilin-1 Modulate the Dynamic Equilibrium of Presenilin-1 and Presenilin-2 γ-Secretase Complexes di Lisa Placanica, Leonid Tarassishin, Guangli Yang, Erica Peethumnongsin, Seonghun Kim, Hui Zheng, Sangram S. Sisodia, Yue‐Ming Li

    Pubblicazione 2008
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  19. 19
    Familial Alzheimer’s mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage site

    Familial Alzheimer’s mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage site di Wen Chen, Eric Gamache, David J. Rosenman, Jian Xie, María M. López, Yue‐Ming Li, Chunyu Wang

    Pubblicazione 2014
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  20. 20
    Modulation of γ-secretase specificity using small molecule allosteric inhibitors

    Modulation of γ-secretase specificity using small molecule allosteric inhibitors di Christopher C. Shelton, Lei Zhu, De-Ming Chau, Li Yang, Rong Wang, Hakim Djaballah, Hui Zheng, Yue‐Ming Li

    Pubblicazione 2009
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