Rezultati

Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice od Meaghan Morris, Giselle M. Knudsen, Sumihiro Maeda, Jonathan C. Trinidad, Alexandra Ioanoviciu, Alma L. Burlingame, Lennart Mucke

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Alzheimer's Disease od Mark Bothwell, Edward Giniger

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Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer’s Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus od Bo Cui, Kang Li, Zhihui Gai, Xiaojun She, Na Zhang, Chuan-Xiang Xu, Xuewei Chen, Gaihong An, Qiang Ma, Rui Wang

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Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau od Xuling Li, Peng Lei, Qing‐zhang Tuo, Scott Ayton, Qiao‐Xin Li, Steve Moon, Irene Volitakis, Rong Liu, Colin L. Masters, David I. Finkelstein, Ashley I. Bush

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Review article What causes alzheimer’s disease? od Richard A. Armstrong

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A systematic review of familial Alzheimer's disease: Differences in presentation of clinical features among three mutated genes and potential ethnic differences od Yat Fung Shea, Leung‐Wing Chu, Angel On-Kei Chan, Joyce Ha, Yan Li, You‐Qiang Song

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A γ‐secretase inhibitor decreases amyloid‐β production in the central nervous system od Randall J. Bateman, Eric Siemers, Kwasi G. Mawuenyega, Guolin Wen, Karen R. Browning, Wendy Sigurdson, Kevin E. Yarasheski, Stuart Friedrich, Ronald B. DeMattos, Patrick C. May, Steven M. Paul, David M. Holtzman

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Insulysin Hydrolyzes Amyloid β Peptides to Products That Are Neither Neurotoxic Nor Deposit on Amyloid Plaques od Atish Mukherjee, Eun-Suk Song, Muthoni Kihiko‐Ehmann, Jack P. Goodman, Jan St. Pyrek, Steven Estus, Louis B. Hersh

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Membrane Topology of γ-Secretase Component PEN-2 od Adam S. Crystal, Vanessa A. Morais, Theodore C. Pierson, Donald S. Pijak, Dan Carlin, Virginia M.‐Y. Lee, Robert W. Doms

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A GPCR/secretase complex regulates β- and γ-secretase specificity for Aβ production and contributes to AD pathogenesis od Lin Teng, Jian Zhao, Feifei Wang, Lan Ma, Gang Pei

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Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-beta by cathepsin D od Uri S. Ladror, Seth W. Snyder, G.T. Wang, Thomas F. Holzman, Grant A. Krafft

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The C‐terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome‐dependent mechanism distinct from γ‐secretase od Janelle Nunan, Mark S. Shearman, Frédéric Checler, Roberto Cappai, Geneviève Evin, Konrad Beyreuther, Colin L. Masters, David H. Small

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Cholinergic Changes in the APP23 Transgenic Mouse Model of Cerebral Amyloidosis od Sonia Boncristiano, Michael E. Calhoun, Peter H. Kelly, Michelle Pfeifer, Luca Bondolfi, Martina Stalder, Amie L. Phinney, Dorothée Abramowski, Christine Stürchler-Pierrat, Albert Enz, Bernd Sommer, Matthias Staufenbiel, Mathias Jucker

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Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and A<b><i>β</i></b>Accumulation od Maja Jazvinšćak Jembrek, Patrick R. Hof, Goran Šimić

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α-Secretase ADAM10 as Well as αAPPs Is Reduced in Platelets and CSF of Alzheimer Disease Patients od Francesca Colciaghi, Barbara Borroni, Lucia Pastorino, Elena Marcello, Martina Zimmermann, Flaminio Cattabeni, Alessandro Padovani, Mónica Di Luca

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Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP od Grant T. Corbett, Frank J. Gonzalez, Kalipada Pahan

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Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other od Chutikarn Butkinaree, Maryssa Canuel, Rachid Essalmani, Steve Poirier, Suzanne Benjannet, Marie‐Claude Asselin, Anna Roubtsova, Josée Hamelin, Jadwiga Marcinkiewicz, Ann Chamberland, Johann Guillemot, Gaétan Mayer, Sangram S. Sisodia, Yves Jacob, Annik Prat, Nabil G. Seidah

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Trafficking of Cell-Surface β-Amyloid Precursor Protein: Evidence that a Sorting Intermediate Participates in Synaptic Vesicle Recycling od Numa R. Marquez-Sterling, Acy Lo, Sangram S. Sisodia, Edward H. Koo

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Amyloid-β Peptides Are Cytotoxic to Oligodendrocytes od Jan Xu, Shawei Chen, S. Hinan Ahmed, Hong Chen, Grace Ku, Mark P. Goldberg, Chung Y. Hsu

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The Evolution of Aβ Peptide Burden in the APP23 Transgenic Mice: Implications for Aβ Deposition in Alzheimer Disease od Yu‐Min Kuo, Thomas G. Beach, Lucia I. Sue, Sarah Scott, Kathryn J. Layne, Tyler A. Kokjohn, Walter M. Kalback, Dean C. Luehrs, Tatiana A. Vishnivetskaya, Dorothée Abramowski, Christine Stürchler-Pierrat, Matthias Staufenbiel, Roy O. Weller, Alex E. Roher

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