Resultados da pesquisa - Yue‐Ming Li

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  1. 1
    The role of astrocytes in amyloid production and Alzheimer's disease

    The role of astrocytes in amyloid production and Alzheimer's disease Por Georgia Frost, Yue‐Ming Li

    Publicado em 2017
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  2. 2
    Physiological and pathological roles of the γ-secretase complex

    Physiological and pathological roles of the γ-secretase complex Por Courtney M. Carroll, Yue‐Ming Li

    Publicado em 2016
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  3. 3
    Turning the tide on Alzheimer’s disease: modulation of γ-secretase

    Turning the tide on Alzheimer’s disease: modulation of γ-secretase Por Joanna E. Luo, Yue‐Ming Li

    Publicado em 2022
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  4. 4
    Isolation and Characterization of a Moderately Thermophilic Anaerobic Alkaliphile, Clostridium paradoxum sp. nov.

    Isolation and Characterization of a Moderately Thermophilic Anaerobic Alkaliphile, Clostridium paradoxum sp. nov. Por Yue‐Ming Li, L. Mandelco, Juergen Wiegel

    Publicado em 1993
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  5. 5
    Complex regulation of γ-secretase: from obligatory to modulatory subunits

    Complex regulation of γ-secretase: from obligatory to modulatory subunits Por Natalya Gertsik, Danica Chiu, Yue‐Ming Li

    Publicado em 2015
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  6. 6
    Gender- and Age-Dependent γ-Secretase Activity in Mouse Brain and Its Implication in Sporadic Alzheimer Disease

    Gender- and Age-Dependent γ-Secretase Activity in Mouse Brain and Its Implication in Sporadic Alzheimer Disease Por Lisa Placanica, Lei Zhu, Yue‐Ming Li

    Publicado em 2009
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  7. 7
    Development and Mechanism of γ-Secretase Modulators for Alzheimer’s Disease

    Development and Mechanism of γ-Secretase Modulators for Alzheimer’s Disease Por Christina J. Crump, Douglas S. Johnson, Yue‐Ming Li

    Publicado em 2013
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  8. 8
    Friend, Foe or Both? Immune Activity in Alzheimer’s Disease

    Friend, Foe or Both? Immune Activity in Alzheimer’s Disease Por Georgia Frost, Lauren A. Jonas, Yue‐Ming Li

    Publicado em 2019
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  9. 9
    Processing of Notch and amyloid precursor protein by γ-secretase is spatially distinct

    Processing of Notch and amyloid precursor protein by γ-secretase is spatially distinct Por Leonid Tarassishin, Ye Ingrid Yin, Bhramdeo Bassit, Yue‐Ming Li

    Publicado em 2004
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  10. 10
    Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain

    Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain Por Xuenian Huang, Xuefeng Lü, Yue‐Ming Li, Xia Li, Jianjun Li

    Publicado em 2014
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  11. 11
    Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus

    Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus Por Xuenian Huang, Mei Chen, Xuefeng Lü, Yue‐Ming Li, Xia Li, Jianjun Li

    Publicado em 2014
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  12. 12
    γ-Secretase Substrate Concentration Modulates the Aβ42/Aβ40 Ratio

    γ-Secretase Substrate Concentration Modulates the Aβ42/Aβ40 Ratio Por Ye Ingrid Yin, Bhramdeo Bassit, Lei Zhu, Xia Yang, Chunyu Wang, Yue‐Ming Li

    Publicado em 2007
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  13. 13
    A Dimeric Smac/Diablo Peptide Directly Relieves Caspase-3 Inhibition by XIAP

    A Dimeric Smac/Diablo Peptide Directly Relieves Caspase-3 Inhibition by XIAP Por Zhonghua Gao, Yuan Tian, Junru Wang, Qian Yin, Hao Wu, Yue Ming Li, Xuejun Jiang

    Publicado em 2007
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  14. 14
    Familial Alzheimer Disease Presenilin-1 Mutations Alter the Active Site Conformation of γ-secretase

    Familial Alzheimer Disease Presenilin-1 Mutations Alter the Active Site Conformation of γ-secretase Por De-Ming Chau, Christina J. Crump, Jennifer C. Villa, David A. Scheinberg, Yue‐Ming Li

    Publicado em 2012
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  15. 15
    GSAP modulates γ-secretase specificity by inducing conformational change in PS1

    GSAP modulates γ-secretase specificity by inducing conformational change in PS1 Por Eitan Wong, George P. Liao, Jerry C. Chang, Peng Xu, Yue‐Ming Li, Paul Greengard

    Publicado em 2019
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  16. 16
    Computer-Aided and AILDE Approaches to Design Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

    Computer-Aided and AILDE Approaches to Design Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors Por Shi, Juan, Gao, Shuang, Wang, Jia-Yu, Ye, Tong, Yue, Ming-Li, Fu, Ying, Ye, Fei

    Publicado em 2022
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  17. 17
    Activation and intrinsic γ-secretase activity of presenilin 1

    Activation and intrinsic γ-secretase activity of presenilin 1 Por Kwangwook Ahn, Christopher C. Shelton, Yuan Tian, Xulun Zhang, M. Lane Gilchrist, Sangram S. Sisodia, Yue‐Ming Li

    Publicado em 2010
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  18. 18
    Pen2 and Presenilin-1 Modulate the Dynamic Equilibrium of Presenilin-1 and Presenilin-2 γ-Secretase Complexes

    Pen2 and Presenilin-1 Modulate the Dynamic Equilibrium of Presenilin-1 and Presenilin-2 γ-Secretase Complexes Por Lisa Placanica, Leonid Tarassishin, Guangli Yang, Erica Peethumnongsin, Seonghun Kim, Hui Zheng, Sangram S. Sisodia, Yue‐Ming Li

    Publicado em 2008
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  19. 19
    Familial Alzheimer’s mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage site

    Familial Alzheimer’s mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage site Por Wen Chen, Eric Gamache, David J. Rosenman, Jian Xie, María M. López, Yue‐Ming Li, Chunyu Wang

    Publicado em 2014
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  20. 20
    Modulation of γ-secretase specificity using small molecule allosteric inhibitors

    Modulation of γ-secretase specificity using small molecule allosteric inhibitors Por Christopher C. Shelton, Lei Zhu, De-Ming Chau, Li Yang, Rong Wang, Hakim Djaballah, Hui Zheng, Yue‐Ming Li

    Publicado em 2009
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