Search Results - Patrick A. Eyers

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  1. 1
    Regulation of Xenopus Aurora A Activation by TPX2

    Regulation of Xenopus Aurora A Activation by TPX2 by Patrick A. Eyers, James L. Maller

    Published 2004
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  2. 2
    The evolving world of pseudoenzymes: proteins, prejudice and zombies

    The evolving world of pseudoenzymes: proteins, prejudice and zombies by Patrick A. Eyers, James M. Murphy

    Published 2016
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  3. 3
    Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease

    Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease by Patrick A. Eyers, Karen Keeshan, Natarajan Kannan

    Published 2016
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  4. 4
    Pseudokinases: Update on Their Functions and Evaluation as New Drug Targets

    Pseudokinases: Update on Their Functions and Evaluation as New Drug Targets by Dominic P. Byrne, Daniel M. Foulkes, Patrick A. Eyers

    Published 2017
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  5. 5
    VX-680 Inhibits Aurora A and Aurora B Kinase Activity in Human Cells

    VX-680 Inhibits Aurora A and Aurora B Kinase Activity in Human Cells by Rebecca K. Tyler, Natalia Shpiro, Rodolfo Márquez, Patrick A. Eyers

    Published 2007
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  6. 6
    Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

    Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution by Patrick A. Eyers, Molly Craxton, Nick Morricel, Philip Cohen, Michel Goedert

    Published 1998
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  7. 7
    A Novel Mechanism for Activation of the Protein Kinase Aurora A

    A Novel Mechanism for Activation of the Protein Kinase Aurora A by Patrick A. Eyers, E Erikson, Lin G. Chen, James L. Maller

    Published 2003
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  8. 8
    Spindle Pole Regulation by a Discrete Eg5-Interacting Domain in TPX2

    Spindle Pole Regulation by a Discrete Eg5-Interacting Domain in TPX2 by Frank Eckerdt, Patrick A. Eyers, Andrea L. Lewellyn, Claude Prigent, James L. Maller

    Published 2008
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  9. 9
    Cataloguing the dead: breathing new life into pseudokinase research

    Cataloguing the dead: breathing new life into pseudokinase research by Safal Shrestha, Dominic P. Byrne, John A. Harris, Natarajan Kannan, Patrick A. Eyers

    Published 2020
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  10. 10
    Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics

    Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics by Nadia Hégarat, Ewan M. Smith, Gowri Nayak, Shunichi Takeda, Patrick A. Eyers, Helfrid Hochegger

    Published 2011
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  11. 11
    Crystal Structure of the Catalytic Domain of the Mitotic Checkpoint Kinase Mps1 in Complex with SP600125

    Crystal Structure of the Catalytic Domain of the Mitotic Checkpoint Kinase Mps1 in Complex with SP600125 by Matthew Ling-Hon Chu, Leonard M. G. Chavas, Kenneth T. Douglas, Patrick A. Eyers, Lydia Tabernero

    Published 2008
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  12. 12
    Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-γ uses a different signaling pathway

    Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-γ uses a different signaling pathway by Pavel Kovarik, Dagmar Stoiber, Patrick A. Eyers, Rossella Menghini, Armin Neininger, Matthias Gaestel, Philip Cohen, Thomas Decker

    Published 1999
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  13. 13
    Tracing the origin and evolution of pseudokinases across the tree of life

    Tracing the origin and evolution of pseudokinases across the tree of life by Annie Kwon, Steven Thomas Scott, Rahil Taujale, Wayland Yeung, Krys J. Kochut, Patrick A. Eyers, Natarajan Kannan

    Published 2019
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  14. 14
    Reduction of Insulin-Stimulated Glucose Uptake in L6 Myotubes by the Protein Kinase Inhibitor SB203580 Is Independent of p38MAPK Activity

    Reduction of Insulin-Stimulated Glucose Uptake in L6 Myotubes by the Protein Kinase Inhibitor SB203580 Is Independent of p38MAPK Activity by Costin N. Antonescu, C. Huang, Wenyan Niu, Zhi Liu, Patrick A. Eyers, Kim A. Heidenreich, Philip J. Bilan, Amira Klip

    Published 2005
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  15. 15
    Paradoxical activation of Raf by a novel Raf inhibitor

    Paradoxical activation of Raf by a novel Raf inhibitor by Clare A Hall-Jackson, Patrick A. Eyers, Philip P. Cohen, Michel Goedert, F. Tom Boyle, Neil Hewitt, Helen Plant, Philip Hedge

    Published 1999
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  16. 16
    Discovery and Exploitation of Inhibitor-resistant Aurora and Polo Kinase Mutants for the Analysis of Mitotic Networks

    Discovery and Exploitation of Inhibitor-resistant Aurora and Polo Kinase Mutants for the Analysis of Mitotic Networks by Paul J. Scutt, Matthew Ling-Hon Chu, Dominic A. Sloane, Mike Cherry, Colin R. Bignell, D. H. Williams, Patrick A. Eyers

    Published 2009
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  17. 17
    Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes

    Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes by Leah Bury, Paula A. Coelho, Angela Simeone, Samantha Ferries, Claire E. Eyers, Patrick A. Eyers, Magdalena Zernicka‐Goetz, David M. Glover

    Published 2017
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  18. 18
    BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL

    BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL by Georgia Greaves, Mateus Milani, Michael Butterworth, Rachel Carter, Dominic P. Byrne, Patrick A. Eyers, Xu Luo, Gerald M. Cohen, Shankar Varadarajan

    Published 2018
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  19. 19
    The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner

    The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner by Fiona P. Bailey, Dominic P. Byrne, Krishnadev Oruganty, Claire E. Eyers, Christopher J. Novotny, Kevan M. Shokat, Natarajan Kannan, Patrick A. Eyers

    Published 2015
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  20. 20
    Classification of Cushing's syndrome PKAc mutants based upon their ability to bind PKI

    Classification of Cushing's syndrome PKAc mutants based upon their ability to bind PKI by Mitchell H. Omar, Maryanne Kihiu, Dominic P. Byrne, Kyung‐Soon Lee, Tyler M. Lakey, Erik Butcher, Patrick A. Eyers, John D. Scott

    Published 2023
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