תוצאות חיפוש

Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck מאת Alexander Hoellein, Anja Pickhard, Fabienne von Keitz, Stephanie Schoeffmann, Guido Piontek, Martina Rudelius, Anja Baumgart, Stefan Wagenpfeil, Christian Peschel, Tobias Dechow, H. Bier, Ulrich Keller

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Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A Review מאת Paschalis Gavriilidis, Alexandros Giakoustidis, Dimitrios Giakoustidis

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Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway מאת Anna Ye, Jovana Deretic, Christopher Hoel, Albert W. Hinman, Daniela Cimini, Julie P. I. Welburn, Thomas J. Maresca

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Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model מאת Daniel Benten, Gunhild Keller, Alexander Quaas, Jörg Schrader, Artur Gontarewicz, Stefan Balabanov, Melanie Braig, Henning Wege, Jürgen Moll, Ansgar W. Lohse, Tim H. Brümmendorf

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Scientific Rationale Supporting the Clinical Development Strategy for the Investigational Aurora A Kinase Inhibitor Alisertib in Cancer מאת Huifeng Niu, Mark Manfredi, Jeffrey Ecsedy

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A Functional Interplay Between Aurora-A, Plk1 and TPX2 at Spindle Poles: Plk1 Controls Centrosomal Localization of Aurora-A and TPX2 Spindle Association מאת Maria De Luca, Patrizia Lavia, Giulia Guarguaglini

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Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2 מאת Kang Zeng, Ricardo Bastos, Francis A. Barr, Ulrike Grüneberg

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Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO‐dependent mechanism מאת Kevin R. Kelly, Steffan T. Nawrocki, Claudia M. Espitia, Mengkun Zhang, Johnny Yang, Swaminathan P. Iyer, Jeffrey Ecsedy, Francis J. Giles, Jennifer S. Carew

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The aurora kinase A regulates GSK-3β in gastric cancer cells מאת A. A. Dar, Abbes Belkhiri, W El-Rifai

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Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest מאת Tiffany A. Coon, Jennifer R. Glasser, Rama K. Mallampalli, Bill B. Chen

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Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells מאת Tomotoshi Marumoto, Shinobu Honda, Toshihiro Hara, Masayuki Nitta, Toru Hirota, Eiji Kohmura, Hideyuki Saya

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The Role of NEDD1 Phosphorylation by Aurora A in Chromosomal Microtubule Nucleation and Spindle Function מאת Roser Pinyol, Jacopo Scrofani, Isabelle Vernos

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Prognostic value of Aurora kinase A (AURKA) expression among solid tumor patients: a systematic review and meta-analysis מאת Jiao Zhang, Baoguo Li, Qing Yang, Pengyu Zhang, Haitao Wang

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Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion מאת T-V Do, Fang Xiao, L. Bickel, Andres J. Klein–Szanto, Harsh B. Pathak, Hua Xiang, Caitlin G. Howe, Shane W. O’Brien, Marsia A. Maglaty, J. Ecsedy, Samuel Litwin, Erica A. Golemis, Russell J. Schilder, Andrew K. Godwin, Denise C. Connolly

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Aurora A Kinase-Coated Beads Function as Microtubule-Organizing Centers and Enhance RanGTP-Induced Spindle Assembly מאת Ming-Ying Tsai, Yixian Zheng

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53 מאת Hiroshi Katayama, Kaori Sasai, Hidehiko Kawai, Zhi-Min Yuan, Jolanta Bondaruk, Fumio Suzuki, Satoshi Fujii, Ralph B. Arlinghaus, Bogdan Czerniak, Subrata Sen

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Bioactive tanshinones in <i>Salvia miltiorrhiza</i> inhibit the growth of prostate cancer cells <i>in vitro</i> and in mice מאת Yi Gong, Yanli Li, Yin Lu, Lin Li, Hamid M. Abdolmaleky, George L. Blackburn, Jin‐Rong Zhou

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Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization מאת Andrew B. Fielding, Iveta Dobreva, Paul C. McDonald, Leonard J. Foster, Shoukat Dedhar

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The GIT-Associated Kinase PAK Targets to the Centrosome and Regulates Aurora-A מאת Zhuo-shen Zhao, Jet Phey Lim, Yuen-Wai Ng, Louis Lim, Ed Manser

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Aurora kinase A controls meiosis I progression in mouse oocytes מאת Adéla Šašková, P Solc, Vladimı́r Baran, Michal Kubelka, Richard M. Schultz, Jan Motlík

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