檢索結果 - Nicolas Bauer
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Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization 由 Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R. Schneider, Xin Zhang, Lena M. Berger, Benedict‐Tilman Berger, Martin P. Schwalm, N. Klopp, Jens T. Siveke, Stefan Knapp, Andreas C. Joerger
出版 2024Artigo -
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Design of a “Two-in-One” Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites 由 Florian Wittlinger, David E. Heppner, Ciric To, Marcel Günther, Bo Hee Shin, Jaimin K. Rana, Anna M. Schmoker, Tyler S. Beyett, Lena M. Berger, Benedict‐Tilman Berger, Nicolas Bauer, James D. Vasta, Cesear Corona, Matthew B. Robers, Stefan Knapp, Pasi A. Jänne, Michael J. Eck, Stefan Laufer
出版 2021Artigo
相關主題
Biochemistry
Biology
Cancer
Cancer research
Chemistry
Gene
Genetics
Acetylation
Allosteric regulation
BRD4
Bromodomain
Cetuximab
Colorectal cancer
Computational biology
EGFR inhibitors
Epidermal growth factor receptor
Erlotinib
Gefitinib
HDAC1
Histone
Histone deacetylase
Mutant
Osimertinib
Pancreatic cancer
Pharmacology
Pharmacophore
Protein kinase domain
Receptor
Small molecule
T790M