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EGFR targeted therapies and radiation: Optimizing efficacy by appropriate drug scheduling and patient selection 著者: Kyle C. Cuneo, Mukesh K. Nyati, Dipankar Ray, Theodore S. Lawrence

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Activation of Multiple ERBB Family Receptors Mediates Glioblastoma Cancer Stem-like Cell Resistance to EGFR-Targeted Inhibition 著者: Paul A. Clark, Mari Iida, Daniel M. Treisman, Haviryaji S. G. Kalluri, Sathyapriya Ezhilan, Michael Zorniak, Deric L. Wheeler, John S. Kuo

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Prognostic and predictive response factors in colorectal cancer patients: Between hope and reality 著者: Chiara De Divitiis

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Comparing ELISA and Surface Plasmon Resonance for Assessing Clinical Immunogenicity of Panitumumab 著者: James A. Lofgren, Sripriya Dhandapani, Jason Pennucci, Christina M. Abbott, Daniel T. Mytych, Arunan Kaliyaperumal, Steven J. Swanson, Michael C. Mullenix

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Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck 著者: Alexander Hoellein, Anja Pickhard, Fabienne von Keitz, Stephanie Schoeffmann, Guido Piontek, Martina Rudelius, Anja Baumgart, Stefan Wagenpfeil, Christian Peschel, Tobias Dechow, H. Bier, Ulrich Keller

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Enhancement of tumor uptake and therapeutic efficacy of EGFR-targeted antibody cetuximab and antibody-drug conjugates by cholesterol sequestration 著者: Yang Chen, Guanghua Liu, Lifang Guo, Hui Wang, Yan Fu, Yongzhang Luo

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Decreased<i>SMAD4</i>expression is associated with induction of epithelial-to-mesenchymal transition and cetuximab resistance in head and neck squamous cell carcinoma 著者: Haixia Cheng, Elana J. Fertig, Hiroyuki Ozawa, Hiromitsu Hatakeyama, Jason D. Howard, Jimena Pérez, Michael Considine, Manjusha Thakar, Ruchira S. Ranaweera, Gabriel Krigsfeld, Christine H. Chung

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Randomized phase 2 study of pegylated SN‐38 (EZN‐2208) or irinotecan plus cetuximab in patients with advanced colorectal cancer 著者: Christopher R. Garrett, Tanios Bekaii‐Saab, Theresa Ryan, George A. Fisher, Sally Clive, Petr Kavan, Einat Shacham‐Shmueli, Aby Buchbinder, Richard M. Goldberg

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Overexpression of CD85j in TNBC patients inhibits Cetuximab‐mediated NK‐cell ADCC but can be restored with CD85j functional blockade 著者: María P. Roberti, Estefanía P. Juliá, Yamila Rocca, Mora Amat, Alicia Bravo, José Loza, Federico Coló, Carlos Martín Loza, Verónica Fabiano, Mercedes Maino, Ariel Podhorzer, Leonardo Fainboim, María Marcela Barrio, José Mordoh, Estrella Mariel Levy

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Epidermal growth factor receptor‐targeted therapy in locally advanced or metastatic squamous cell carcinoma of the penis 著者: Bradley Curtis Carthon, Chaan S. Ng, Curtis A. Pettaway, Lance C. Pagliaro

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A population‐based study of therapy and survival for patients with head and neck cancer treated in the community 著者: Claudio Dansky Ullmann, Linda C. Harlan, Vickie L. Shavers, Jennifer Stevens

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Meta-analysis of <i>KRAS</i> mutations and survival after resection of colorectal liver metastases 著者: Kristoffer W. Brudvik, Scott Kopetz, L. Li, Claudius Conrad, Thomas A. Aloia, Jean‐Nicolas Vauthey

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Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the “THERAPY”phase 1-2 trial... 著者: Eric Assénat, D. Azria, Caroline Mollévi, Rosine Guimbaud, N. Tubiana-Mathieu, Denis Smith, Jean‐Pierre Delord, Emmanuelle Samalin, Fabienne Portales, Christel Larbouret, Bruno Robert, Frédéric Bibeau, Jean‐Pierre Bleuse, Evelyne Lopez‐Crapez, Marc Ychou, André Pèlegrin

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The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells 著者: Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa

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The Plasticity of Oncogene Addiction: Implications for Targeted Therapies Directed to Receptor Tyrosine Kinases 著者: Vinochani Pillay, Layal Allaf, Alexander L. Wilding, Jacqueline F. Donoghue, Naomi W. Court, Sameer A. Greenall, Andrew M. Scott, Terrance G. Johns

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Phase 1 and pharmacokinetic study of everolimus in combination with cetuximab and carboplatin for recurrent/metastatic squamous cell carcinoma of the head and neck 著者: Nabil F. Saba, Selwyn J. Hurwitz, Kelly R. Magliocca, Sungjin Kim, Taofeek K. Owonikoko, Donald Harvey, Suresh S. Ramalingam, Zhengjia Chen, Jackie Rogerio, Jennifer R. Mendel, Scott A. Kono, Colleen Lewis, Amy Y. Chen, Kristin Higgins, Mark W. El‐Deiry, Trad Wadsworth, Jonathan J. Beitler, Dong M. Shin, Shi‐Yong Sun, Fadlo R. Khuri

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Integrating novel therapeutic monoclonal antibodies into the management of head and neck cancer 著者: Julie E. Bauman, Robert L. Ferris

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Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer 著者: Ryan Hutchinson, Richard Adams, Darragh G. McArt, Manuel Salto‐Tellez, Bharat Jasani, Peter W. Hamilton

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Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer 著者: Friederike Braig, Manuela März, Aneta Schieferdecker, Alexander Schulte, Mareike Voigt, Alexander Stein, Tobias Grob, Malik Alawi, Daniela Indenbirken, Malte Kriegs, Erik Engel, U. Vanhoefer, Adam Grundhoff, Sonja Loges, Kristoffer Riecken, Boris Fehse, Carsten Bokemeyer, Mascha Binder

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A randomized phase 2 trial of gemcitabine/cisplatin with or without cetuximab in patients with advanced urothelial carcinoma 著者: Maha Hussain, Stephanie Daignault, Neeraj Agarwal, Petros Grivas, Arlene O. Siefker‐Radtke, Igor Puzanov, Gary R. MacVicar, Ellis Levine, Sandy Srinivas, Przemyslaw Twardowski, Mario A. Eisenberger, David I. Quinn, Ulka N. Vaishampayan, Evan Y. Yu, Scott J. Dawsey, Kathleen C. Day, Mark L. Day, Mahmoud Al‐Hawary, David C. Smith

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