Výsledky vyhledávání - Matthew G. Rees

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  1. 1
    Glucokinase regulatory protein

    Glucokinase regulatory protein Autor Anne Raimondo, Matthew G. Rees, Anna L. Gloyn

    Vydáno 2015
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  2. 2
    Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk

    Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk Autor Matthew G. Rees, Stephen Wincovitch, Julia Schultz, Rica Waterstradt, Nicola L. Beer, Simone Baltrusch, Francis S. Collins, Anna L. Gloyn

    Vydáno 2011
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  3. 3
    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes

    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes Autor Drew Adams, Daisuke Ito, Matthew G. Rees, Brinton Seashore‐Ludlow, Xiaoling Puyang, Alex H. Ramos, Jaime H. Cheah, Paul A. Clemons, Markus Warmuth, Ping Zhu, Alykhan F. Shamji, Stuart L. Schreiber

    Vydáno 2014
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  4. 4
    Methionine synthase is essential for cancer cell proliferation in physiological folate environments

    Methionine synthase is essential for cancer cell proliferation in physiological folate environments Autor Mark R. Sullivan, Alicia M. Darnell, Montana F. Reilly, Tenzin Kunchok, Lena Joesch-Cohen, Daniel W. Rosenberg, Ahmed Ali, Matthew G. Rees, Jennifer A. Roth, Caroline A. Lewis, Matthew G. Vander Heiden

    Vydáno 2021
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  5. 5
    Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions

    Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions Autor Owen S. Skinner, Joan Blanco-Fernández, Russell P. Goodman, Akinori Kawakami, Hongying Shen, Lajos V. Kemény, Lena Joesch-Cohen, Matthew G. Rees, Jennifer A. Roth, David E. Fisher, Vamsi K. Mootha, Alexis A. Jourdain

    Vydáno 2023
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  6. 6
    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery Autor Natalie Boehnke, Joelle P. Straehla, Hannah C. Safford, Mustafa Kocak, Matthew G. Rees, Melissa M. Ronan, Danny Rosenberg, Charles H. Adelmann, Raghu R. Chivukula, Namita Nabar, Adam G. Berger, Nicholas G. Lamson, Jaime H. Cheah, Hojun Li, Jennifer A. Roth, Angela N. Koehler, Paula T. Hammond

    Vydáno 2022
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  7. 7
    Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors

    Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors Autor Wenchao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B. Ficarro, Isidoro Tavares, Jianwei Che, Audrey Y. Kim, Xijun Zhu, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Stephen M. Hinshaw, Behnam Nabet, Steven M. Corsello, Nicholas Kwiatkowski, Jarrod A. Marto, Tinghu Zhang, Nathanael S. Gray

    Vydáno 2023
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  8. 8
    Targeted degradation of CDK9 potently disrupts the MYC-regulated network

    Targeted degradation of CDK9 potently disrupts the MYC-regulated network Autor Mohammed A. Toure, Keisuke Motoyama, Yichen Xiang, Julie Urgiles, Florian Kabinger, Ann-Sophie Koglin, Ramya S. Iyer, Kaitlyn Gagnon, Amruth Kumar, Samuel Ojeda, Drew A. Harrison, Matthew G. Rees, Jennifer A. Roth, Christopher J. Ott, Richard P. Schiavoni, Charles A. Whittaker, Stuart S. Levine, Forest M. White, Eliezer Calo, André Richters, Angela N. Koehler

    Vydáno 2025
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  9. 9
    Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics

    Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics Autor Luc de Waal, Timothy A. Lewis, Matthew G. Rees, Aviad Tsherniak, Xiaoyun Wu, Peter S. Choi, Lara Gechijian, Christina R. Hartigan, Patrick W. Faloon, Mark J. Hickey, Nicola Tolliday, Steven A. Carr, Paul A. Clemons, Benito Muñoz, Bridget K. Wagner, Alykhan F. Shamji, Angela N. Koehler, Monica Schenone, Alex B. Burgin, Stuart L. Schreiber, Heidi Greulich, Matthew Meyerson

    Vydáno 2015
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  10. 10
    DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with<i>In Silico</i>Analysis to Identify Novel Therapeutic Targets

    DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with<i>In Silico</i>Analysis to Identify Novel Therapeutic Targets Autor Allison R. Hanaford, Tenley C. Archer, Antoinette Price, Ulf D. Kahlert, Jarek Maciaczyk, Guido Nikkhah, Jong Wook Kim, Tobias Ehrenberger, Paul A. Clemons, Vlado Dančík, Brinton Seashore‐Ludlow, Vasanthi S. Viswanathan, Michelle L. Stewart, Matthew G. Rees, Alykhan Shamji, Stuart L. Schreiber, Ernest Fraenkel, Scott L. Pomeroy, Jill P. Mesirov, Pablo Tamayo, Charles G. Eberhart, Eric H. Raabe

    Vydáno 2016
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  11. 11
    INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors

    INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors Autor Qing Li, Baishan Jiang, Jiaye Guo, Hong Shao, Isabella Del Priore, Qing Chang, Rei Kudo, Zhiqiang Li, Pedram Razavi, Bo Liu, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Katherine A. Donovan, Marta Palafox, Jorge S. Reis‐Filho, Elisa de Stanchina, Eric S. Fischer, Neal Rosen, Violeta Serra, Andrew Koff, John D. Chodera, Nathanael S. Gray, Sarat Chandarlapaty

    Vydáno 2021
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  12. 12
    Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling

    Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling Autor Mengyang Fan, Wenchao Lu, Jianwei Che, Nicholas Kwiatkowski, Yang Gao, Hyuk‐Soo Seo, Scott B. Ficarro, Prafulla C. Gokhale, Yao Liu, Ezekiel A. Geffken, Jimit Lakhani, Kijun Song, Miljan Kuljanin, Wenzhi Ji, Jie Jiang, Zhixiang He, Jason Tse, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Joseph D. Mancias, Jarrod A. Marto, Sirano Dhe‐Paganon, Tinghu Zhang, Nathanael S. Gray

    Vydáno 2022
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  13. 13
    Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset

    Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset Autor Brinton Seashore‐Ludlow, Matthew G. Rees, Jaime H. Cheah, Murat Cokol, Edmund V. Price, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Joshua Gould, Benjamin Alexander, Ava Li, Philip Montgomery, Mathias J. Wawer, Nurdan Kuru, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Joshua A. Bittker, Michelle Palmer, James E. Bradner, Alykhan F. Shamji, Paul A. Clemons, Stuart L. Schreiber

    Vydáno 2015
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  14. 14
    Correlating chemical sensitivity and basal gene expression reveals mechanism of action

    Correlating chemical sensitivity and basal gene expression reveals mechanism of action Autor Matthew G. Rees, Brinton Seashore‐Ludlow, Jaime H. Cheah, Drew Adams, Edmund V. Price, Shubhroz Gill, Sarah Javaid, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Benjamin Alexander, Ava Li, Philip Montgomery, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Daniel A. Haber, Clary B. Clish, Joshua A. Bittker, Michelle Palmer, Bridget K. Wagner, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber

    Vydáno 2015
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  15. 15
    Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer

    Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer Autor Elizabeth H. Stover, Maria B. Baco, Ofir Cohen, Yvonne Y. Li, Elizabeth L. Christie, Mukta Bagul, Amy Goodale, Yenarae Lee, Sasha Pantel, Matthew G. Rees, Guo Wei, Adam G. Presser, Maya K. Gelbard, Weiqun Zhang, Ioannis K. Zervantonakis, Patrick Bhola, Jeremy Ryan, Jennifer L. Guerriero, Joan Montero, Felice J. Liang, Andrew D. Cherniack, Federica Piccioni, Ursula A. Matulonis, David D.L. Bowtell, Kristopher A. Sarosiek, Anthony Letai, Levi A. Garraway, Cory M. Johannessen, Matthew Meyerson

    Vydáno 2019
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  16. 16
    Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers

    Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers Autor Marc Payton, Brian Belmontes, Kelly Hanestad, Jodi Moriguchi, Kui Chen, John D. McCarter, Grace Chung, Maria Stefania S. Ninniri, Jan Sun, Raffi Manoukian, Stuart Chambers, Seok‐Man Ho, Robert J. Kurzeja, Katheryne Z. Edson, Upendra P. Dahal, Tian Wu, Sharon Wannberg, Pedro J. Beltran, Jude Canon, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Sheroy Minocherhomji, Matthew P. Bourbeau, Jennifer R. Allen, Angela Coxon, Nuria Tamayo, Paul E. Hughes

    Vydáno 2023
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  17. 17
    MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors

    MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors Autor Thomas P. Howard, Taylor E. Arnoff, Melinda R. Song, Andrew O. Giacomelli, Xiaofeng Wang, Andrew L. Hong, Neekesh V. Dharia, Su Wang, Francisca Vázquez, Minh‐Tam Pham, Ann M. Morgan, Franziska Wachter, Gregory H. Bird, Guillaume Kugener, Elaine M. Oberlick, Matthew G. Rees, Hong L. Tiv, Justin H. Hwang, Katherine H. Walsh, April Cook, John M. Krill-Burger, Aviad Tsherniak, Prafulla C. Gokhale, Peter J. Park, Kimberly Stegmaier, Loren D. Walensky, William C. Hahn, Charles W.M. Roberts

    Vydáno 2019
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  18. 18
    Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

    Discovering the anticancer potential of non-oncology drugs by systematic viability profiling Autor Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler, Jordan Rossen, Mustafa Kocak, Jordan Bryan, Ranad Humeidi, D. D. Peck, Xiaoyun Wu, Andrew Tang, Vickie M. Wang, Samantha Bender, Evan Lemire, Rajiv Narayan, Philip Montgomery, Uri Ben‐David, Colin W. Garvie, Yejia Chen, Matthew G. Rees, Nicholas Lyons, James M. McFarland, Bang Wong, Li Wang, Nancy Dumont, Patrick J. O’Hearn, Eric Stefan, John G. Doench, Caitlin Harrington, Heidi Greulich, Matthew Meyerson, Francisca Vázquez, Aravind Subramanian, Jennifer A. Roth, Joshua A. Bittker, Jesse S. Boehm, Christopher C. Mader, Aviad Tsherniak, Todd R. Golub

    Vydáno 2020
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  19. 19
    Screening in serum-derived medium reveals differential response to compounds targeting metabolism

    Screening in serum-derived medium reveals differential response to compounds targeting metabolism Autor Keene L. Abbott, Ahmed Ali, Dominick Casalena, T. Brian, Raphaël Ferreira, Jaime H. Cheah, Christian K. Soule, Amy Deik, Tenzin Kunchok, Daniel R. Schmidt, Steffen Renner, Sophie Honeder, Michelle Xiao Wu, Sze Ham Chan, Tenzin Tseyang, Andrew T. Stoltzfus, Sarah L. J. Michel, Daniel Greaves, Peggy P. Hsu, Christopher Ng, Chelsea J. Zhang, Ali Farsidjani, Johnathan R. Kent, Maria Lucia L. Madariaga, Iva Monique T. Gramatikov, Nicholas J. Matheson, Caroline A. Lewis, Clary B. Clish, Matthew G. Rees, Jennifer A. Roth, Lesley A. Mathews Griner, Alexander Muir, Douglas S. Auld, Matthew G. Vander Heiden

    Vydáno 2023
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  20. 20
    Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

    Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway Autor Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv, Shubhroz Gill, Ossia M. Eichhoff, Brinton Seashore‐Ludlow, Samuel D. Kaffenberger, John K. Eaton, Kaoru Shimada, Andrew J. Aguirre, Srinivas R. Viswanathan, Shrikanta Chattopadhyay, Pablo Tamayo, Wan Seok Yang, Matthew G. Rees, Sixun Chen, Žarko Bošković, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen-Yi Tseng, Elisabeth Roider, Dong Gao, James M. Cleary, Brian M. Wolpin, Jill P. Mesirov, Daniel A. Haber, Jeffrey A. Engelman, Jesse S. Boehm, Joanne Kotz, Cindy Hon, Yu Chen, William C. Hahn, Mitchell P. Levesque, John G. Doench, Michael E. Berens, Alykhan F. Shamji, Paul A. Clemons, Brent R. Stockwell, Stuart L. Schreiber

    Vydáno 2017
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