Kết quả tìm kiếm - Joshua A. Bittker
- Đang hiển thị 1 - 20 kết quả của 20
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1
Nucleic acid evolution and minimization by nonhomologous random recombination Bằng Joshua A. Bittker, Brian V. Le, David R. Liu
Được phát hành 2002Artigo -
2
Development of small-molecule probes that selectively kill cells induced to express mutant RAS Bằng Michel Weïwer, Joshua A. Bittker, Timothy A. Lewis, Kaoru Shimada, Wan Seok Yang, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Brent R. Stockwell, Stuart L. Schreiber, Benito Muñoz
Được phát hành 2011Artigo -
3
Small-molecule inducers of insulin expression in pancreatic α-cells Bằng Dina Fomina‐Yadlin, Stefan Kubicek, Deepika Walpita, Vlado Dančík, Jacob Hecksher‐Sørensen, Joshua A. Bittker, Tanaz Sharifnia, Alykhan F. Shamji, Paul A. Clemons, Bridget K. Wagner, Stuart L. Schreiber
Được phát hành 2010Artigo -
4
Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis Bằng Sae Woong Park, Dominick Casalena, Daniel J. Wilson, R. Dai, Partha P. Nag, Feng Liu, Jim P. Boyce, Joshua A. Bittker, Stuart L. Schreiber, B.C. Finzel, Dirk Schnappinger, Courtney C. Aldrich
Được phát hành 2014Artigo -
5
High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding Bằng Wei‐Chung Chiang, Yongjie Wei, Yi-Chun Kuo, Shuguang Wei, Anwu Zhou, Zhongju Zou, Jenna Yehl, Matthew J. Ranaghan, Adam Skepner, Joshua A. Bittker, José R. Perez, Bruce A. Posner, Beth Levine
Được phát hành 2018Artigo -
6
The Drug Repurposing Hub: a next-generation drug library and information resource Bằng Steven M. Corsello, Joshua A. Bittker, Zihan Liu, Joshua Gould, Patrick McCarren, Jodi Hirschman, Stephen Johnston, Anita Vrcic, Bang Wong, Mariya Khan, Jacob K. Asiedu, Rajiv Narayan, Christopher C. Mader, Aravind Subramanian, Todd R. Golub
Được phát hành 2017Carta -
7
Evolving BioAssay Ontology (BAO): modularization, integration and applications Bằng Saminda Abeyruwan, Uma D. Vempati, Hande Küçük‐McGinty, Ubbo Visser, Amar Koleti, Ahsan Mir, Kunie Sakurai, Caty Chung, Joshua A. Bittker, Paul A. Clemons, Steve Brudz, Anosha D. Siripala, Arturo J. Morales, Martin Romacker, David Twomey, Svetlana Bureeva, Vance Lemmon, Stephan C. Schürer
Được phát hành 2014Artigo -
8
Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease Bằng Elizaveta S. Leshchiner, Jason S. Rush, Michael A. Durney, Zhifang Cao, Vlado Dančík, Benjamin Chittick, Huixian Wu, Adam Petrone, Joshua A. Bittker, Andrew J. Phillips, José R. Perez, Alykhan F. Shamji, Virendar K. Kaushik, Mark J. Daly, Daniel B. Graham, Stuart L. Schreiber, Ramnik J. Xavier
Được phát hành 2017Artigo -
9
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay Bằng Mark‐Anthony Bray, Sigrun Gustafsdottir, Mohammad Hossein Rohban, Shantanu Singh, Vebjorn Ljosa, Katherine L Sokolnicki, Joshua A. Bittker, Nicole E. Bodycombe, Vlado Dančík, Thomas P. Hasaka, Cindy Hon, Melissa M. Kemp, Kejie Li, Deepika Walpita, Mathias J. Wawer, Todd R. Golub, Stuart L. Schreiber, Paul A. Clemons, Alykhan F. Shamji, Anne E. Carpenter
Được phát hành 2017Artigo -
10
Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes Bằng Kfir Sharabi, Hua Lin, Clint D.J. Tavares, John E. Dominy, João Paulo Camporez, Rachel J. Perry, Roger Schilling, Amy K. Rines, Jaemin Lee, Marc Hickey, Melissa Bennion, Michelle Palmer, Partha P. Nag, Joshua A. Bittker, José R. Perez, Mark P. Jedrychowski, Umut Özcan, Steve P. Gygi, Theodore M. Kamenecka, Gerald I. Shulman, Stuart L. Schreiber, Patrick R. Griffin, Pere Puigserver
Được phát hành 2017Artigo -
11
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling Bằng Mathias J. Wawer, Kejie Li, Sigrun Gustafsdottir, Vebjorn Ljosa, Nicole E. Bodycombe, Melissa A. Marton, Katherine L Sokolnicki, Mark‐Anthony Bray, Melissa M. Kemp, Ellen Winchester, Bradley R Taylor, George Grant, C. Suk-Yee Hon, Jeremy R. Duvall, Joshua Wilson, Joshua A. Bittker, Vlado Dančík, Rajiv Narayan, Aravind Subramanian, Wendy Winckler, Todd R. Golub, Anne E. Carpenter, Alykhan F. Shamji, Stuart L. Schreiber, Paul A. Clemons
Được phát hành 2014Artigo -
12
Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset Bằng Brinton Seashore‐Ludlow, Matthew G. Rees, Jaime H. Cheah, Murat Cokol, Edmund V. Price, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Joshua Gould, Benjamin Alexander, Ava Li, Philip Montgomery, Mathias J. Wawer, Nurdan Kuru, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Joshua A. Bittker, Michelle Palmer, James E. Bradner, Alykhan F. Shamji, Paul A. Clemons, Stuart L. Schreiber
Được phát hành 2015Artigo -
13
Correlating chemical sensitivity and basal gene expression reveals mechanism of action Bằng Matthew G. Rees, Brinton Seashore‐Ludlow, Jaime H. Cheah, Drew Adams, Edmund V. Price, Shubhroz Gill, Sarah Javaid, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Benjamin Alexander, Ava Li, Philip Montgomery, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Daniel A. Haber, Clary B. Clish, Joshua A. Bittker, Michelle Palmer, Bridget K. Wagner, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber
Được phát hành 2015Artigo -
14
Genetic and transcriptional evolution alters cancer cell line drug response Bằng Uri Ben‐David, Benjamin A. Siranosian, Gavin Ha, Helen Tang, Yaara Oren, Kunihiko Hinohara, Craig A. Strathdee, Joshua M. Dempster, Nicholas Lyons, Robert Burns, Anwesha Nag, Guillaume Kugener, Beth A. Cimini, Peter Tsvetkov, Yosef E. Maruvka, Ryan O’Rourke, Anthony J. Garrity, Andrew A. Tubelli, Pratiti Bandopadhayay, Aviad Tsherniak, Francisca Vázquez, Bang Wong, Chet Birger, Mahmoud Ghandi, Aaron R. Thorner, Joshua A. Bittker, Matthew Meyerson, Gad Getz, Rameen Beroukhim, Todd R. Golub
Được phát hành 2018Artigo -
15
An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules Bằng Amrita Basu, Nicole E. Bodycombe, Jaime H. Cheah, Edmund V. Price, Ke Liu, Giannina I. Schaefer, Richard Y. Ebright, Michelle L. Stewart, Daisuke Ito, Stephanie Wang, Abigail Bracha, Ted Liefeld, Mathias J. Wawer, Joshua C. Gilbert, Andrew J. Wilson, Nicolas Stransky, Gregory V. Kryukov, Vlado Dančík, Jordi Barretina, Levi A. Garraway, C. Suk-Yee Hon, Benito Muñoz, Joshua A. Bittker, Brent R. Stockwell, Dineo Khabele, Andrew M. Stern, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber
Được phát hành 2013Artigo -
16
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling Bằng Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler, Jordan Rossen, Mustafa Kocak, Jordan Bryan, Ranad Humeidi, D. D. Peck, Xiaoyun Wu, Andrew Tang, Vickie M. Wang, Samantha Bender, Evan Lemire, Rajiv Narayan, Philip Montgomery, Uri Ben‐David, Colin W. Garvie, Yejia Chen, Matthew G. Rees, Nicholas Lyons, James M. McFarland, Bang Wong, Li Wang, Nancy Dumont, Patrick J. O’Hearn, Eric Stefan, John G. Doench, Caitlin Harrington, Heidi Greulich, Matthew Meyerson, Francisca Vázquez, Aravind Subramanian, Jennifer A. Roth, Joshua A. Bittker, Jesse S. Boehm, Christopher C. Mader, Aviad Tsherniak, Todd R. Golub
Được phát hành 2020Artigo -
17
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells Bằng Kimberly A. Hartwell, Peter G. Miller, Siddhartha Mukherjee, Alissa R. Kahn, Alison L. Stewart, David J. Logan, Joseph Negri, Mildred Duvet, Marcus Järås, Rishi V. Puram, Vlado Dančík, Fátima Al‐Shahrour, Thomas Kindler, Zuzana Tóthová, Shrikanta Chattopadhyay, Thomas P. Hasaka, Rajiv Narayan, Mingji Dai, Christina Huang, Sebastian Shterental, Lisa P. Chu, J. Erika Haydu, Jae Hung Shieh, David P. Steensma, Benito Muñoz, Joshua A. Bittker, Alykhan F. Shamji, Paul A. Clemons, Nicola Tolliday, Anne E. Carpenter, D. Gary Gilliland, Andrew M. Stern, Malcolm A.S. Moore, David T. Scadden, Stuart L. Schreiber, Benjamin L. Ebert, Todd R. Golub
Được phát hành 2013Artigo -
18
A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles Bằng Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub
Được phát hành 2017Pré-impressão -
19
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors Bằng Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato, Arvind Sharma, Manmohan Sharma, Micah Maetani, Jessica Bastien, Nicolas M. B. Brancucci, Joshua A. Bittker, Victoria Corey, David C. Clarke, Emily R. Derbyshire, Gillian L. Dornan, Sandra Duffy, Sean Eckley, Maurice A. Itoe, Karin M. J. Koolen, Timothy A. Lewis, Ping S. Lui, Amanda K. Lukens, Emily Lund, Sandra March, Elamaran Meibalan, Bennett C. Meier, Jacob A. McPhail, Branko Mitasev, Eli L. Moss, Morgane Sayes, Yvonne Van Gessel, Mathias J. Wawer, Takashi Yoshinaga, Anne‐Marie Zeeman, Vicky M. Avery, Sangeeta N. Bhatia, John E. Burke, Flaminia Catteruccia, Jon Clardy, Paul A. Clemons, Koen J. Dechering, Jeremy R. Duvall, Michael A. Foley, Fabian Gusovsky, Clemens H. M. Kocken, Matthias Marti, Marshall Morningstar, Benito Muñoz, Daniel E. Neafsey, Amit Sharma, Elizabeth A. Winzeler, Dyann F. Wirth, Christina Scherer, Stuart L. Schreiber
Được phát hành 2016Artigo -
20
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles Bằng Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Sarah Johnson, Nicholas Lyons, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Roger Hu, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Peyton Greenside, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub
Được phát hành 2017Artigo
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Biology
Computational biology
Genetics
Computer science
Gene
Biochemistry
Bioinformatics
Medicine
Chemistry
Small molecule
Cancer
Cell
Cell biology
Cell culture
Drug discovery
Gene expression
Artificial intelligence
Cancer cell
Drug
High-throughput screening
Immunology
Operating system
Pathology
Pharmacology
Profiling (computer programming)
Biotin
Cancer research
Computer network
Disease
Drug development