Search Results - Jean‐Vianney Haure‐Mirande

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  1. 1
    Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2

    Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2 by Jean‐Vianney Haure‐Mirande, Mickaël Audrain, Michelle E. Ehrlich, Sam Gandy

    Published 2022
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  2. 2
    Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice

    Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice by Mickaël Audrain, Jean‐Vianney Haure‐Mirande, Justyna Mleczko, Minghui Wang, Jennifer K. Griffin, Peter St George–Hyslop, Paul E. Fraser, Bin Zhang, Sam Gandy, Michelle E. Ehrlich

    Published 2020
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  3. 3
    TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration

    TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astroglios... by Jordi Creus‐Muncunill, Jean‐Vianney Haure‐Mirande, Daniele Mattei, Joanna Bons, Angie V. Ramirez, B. Wade Hamilton, Chuhyon Corwin, Sarah Chowdhury, Birgit Schilling, Lisa Ellerby, Michelle E. Ehrlich

    Published 2024
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  4. 4
    Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden

    Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathol... by Jean‐Vianney Haure‐Mirande, Minghui Wang, Mickaël Audrain, Tomas Fanutza, Soong Ho Kim, Szilvia Heja, Ben Readhead, Joel T. Dudley, Robert D. Blitzer, Eric E. Schadt, Bin Zhang, Sam Gandy, Michelle E. Ehrlich

    Published 2018
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  5. 5
    Microglial <i>INPP5D</i> limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease

    Microglial <i>INPP5D</i> limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease by Emilie L. Castranio, Philip Hasel, Jean‐Vianney Haure‐Mirande, Angie V. Ramirez Jimenez, B. Wade Hamilton, Rachel D. Kim, Charles Glabe, Minghui Wang, Bin Zhang, Sam Gandy, Shane A. Liddelow, Michelle E. Ehrlich

    Published 2022
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  6. 6
    Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology

    Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology by Jean‐Vianney Haure‐Mirande, Mickaël Audrain, Tomas Fanutza, Soong Ho Kim, William L. Klein, Charles Glabe, Ben Readhead, Joel T. Dudley, Robert D. Blitzer, Minghui Wang, Bin Zhang, Eric E. Schadt, Sam Gandy, Michelle E. Ehrlich

    Published 2017
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  7. 7
    Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau

    Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and stat... by Mickaël Audrain, Jean‐Vianney Haure‐Mirande, Minghui Wang, Soong Ho Kim, Tomas Fanutza, Paramita Chakrabarty, Paul E. Fraser, Peter St George‐Hyslop, Todd E. Golde, Robert D. Blitzer, Eric E. Schadt, Bin Zhang, Michelle E. Ehrlich, Sam Gandy

    Published 2018
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  8. 8
    Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

    Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus by Ben Readhead, Jean‐Vianney Haure‐Mirande, Cory C. Funk, Matthew A. Richards, Paul Shannon, Vahram Haroutunian, Mary Sano, Winnie S. Liang, Noam D. Beckmann, Nathan D. Price, Eric M. Reiman, Eric E. Schadt, Michelle E. Ehrlich, Sam Gandy, Joel T. Dudley

    Published 2018
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  9. 9
    Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease

    Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease by Noam D. Beckmann, Wei‐Jye Lin, Minghui Wang, Ariella Cohain, Alexander W. Charney, Pei Wang, Weiping Ma, Ying‐Chih Wang, Cheng Jiang, Mickaël Audrain, Phillip Comella, Amanda K. Fakira, Siddharth Hariharan, Gillian M. Belbin, Kiran Girdhar, Allan I. Levey, Nicholas T. Seyfried, Eric B. Dammer, Duc M. Duong, James J. Lah, Jean‐Vianney Haure‐Mirande, Ben Shackleton, Tomas Fanutza, Robert D. Blitzer, Eimear E. Kenny, Jun Zhu, Vahram Haroutunian, Pavel Katsel, Sam Gandy, Zhidong Tu, Michelle E. Ehrlich, Bin Zhang, Stephen R. Salton, Eric E. Schadt

    Published 2020
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  10. 10
    Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

    Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models by Ying‐Wooi Wan, Rami Al‐Ouran, Carl Grant Mangleburg, Thanneer M. Perumal, Tom V. Lee, Katherine Allison, Vivek Swarup, Cory C. Funk, Chris Gaiteri, Mariet Allen, Minghui Wang, Sarah M. Neuner, Catherine C. Kaczorowski, Vivek M. Philip, Gareth R. Howell, Heidi Martini‐Stoica, Hui Zheng, Hongkang Mei, Xiaoyan Zhong, Jungwoo Wren Kim, Valina L. Dawson, Ted M. Dawson, Ping‐Chieh Pao, Li‐Huei Tsai, Jean‐Vianney Haure‐Mirande, Michelle E. Ehrlich, Paramita Chakrabarty, Yona Levites, Xue Wang, Eric B. Dammer, Gyan Srivastava, Sumit Mukherjee, Solveig K. Sieberts, Larsson Omberg, Kristen K. Dang, James A. Eddy, Phil Snyder, Yooree Chae, Sandeep Amberkar, Wenbin Wei, Yoshihide Hayashizaki, Christoph Preuß, Ayla Ergün, Phillip J. Ebert, David Airey, Sara Mostafavi, Lei Yu, Hans‐Ulrich Klein, Gregory W. Carter, David Collier, Todd E. Golde, Allan I. Levey, David A. Bennett, Karol Estrada, T. Matthew Townsend, Bin Zhang, Eric E. Schadt, Philip L. De Jager, Nathan D. Price, Nilüfer Ertekin‐Taner, Zhandong Liu, Joshua M. Shulman, Lara M. Mangravite, Benjamin A. Logsdon

    Published 2020
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