Resultats de la cerca

A <scp><i>TREM</i></scp><i>1</i> variant alters the accumulation of Alzheimer‐related amyloid pathology per Joseph M. Replogle, Gail Chan, Charles C. White, Towfique Raj, Phoebe A. Winn, Denis A. Evans, Reisa A. Sperling, Lori B. Chibnik, Elizabeth M. Bradshaw, Julie A. Schneider, David A. Bennett, Philip L. De Jager

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DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response per Li Zhong, Xiao‐Fen Chen, Zhen-Lian Zhang, Zhe Wang, Xin-Zhen Shi, Kai Xu, Yun‐wu Zhang, Huaxi Xu, Guojun Bu

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Heterogeneous expression of the triggering receptor expressed on myeloid cells‐2 on adult murine microglia per Christoph D. Schmid, Lauren N. Sautkulis, Patria E. Danielson, Judith R. Cooper, Karl W. Hasel, Brian S. Hilbush, J. Gregor Sutcliffe, Monica J. Carson

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<i>TREM2</i>and Neurodegenerative Disease per Rita Guerreiro, John Hardy

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Genetic Determinants of Disease Progression in Alzheimer's Disease per Xingbin Wang, Oscar L. López, Robert A. Sweet, James T. Becker, Steven T. DeKosky, M. Michael Barmada, F. Yesim Demirci, M. Ilyas Kamboh

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Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) per Yuka Atagi, Chia‐Chen Liu, Meghan M. Painter, Xiao‐Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S. Kang, Huaxi Xu, Steven G. Younkin, Pritam Das, John Denis Fryer, Guojun Bu

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CD33 modulates TREM2: convergence of Alzheimer loci per Gail Chan, Charles C. White, Phoebe A. Winn, Maria Cimpean, Joseph M. Replogle, Laura Glick, Nicole Cuerdon, Katie J. Ryan, Keith A. Johnson, Julie A. Schneider, David A. Bennett, Lori B. Chibnik, Reisa A. Sperling, Elizabeth M. Bradshaw, Philip L. De Jager

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A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia per Raffaele Ferrari, Mario Grassi, Erika Salvi, Barbara Borroni, Fernando Palluzzi, Daniele Pepe, Francesca D’Avila, Alessandro Padovani, Silvana Archetti, Innocenzo Rainero, Elisa Rubino, Lorenzo Pinessi, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Daniela Galimberti, Elio Scarpini, María Serpente, Giacomina Rossi, Giorgio Giaccone, Fabrizio Tagliavini, Benedetta Nacmias, Irene Piaceri, Silvia Bagnoli, Amalia C. Bruni, Raffaele Maletta, Livia Bernardi, Alfredo Postiglione, Graziella Milan, M. Franceschi, Annibale Alessandro Puca, Valeria Novelli, Cristina Barlassina, Nicola Glorioso, Paolo Manunta, Andrew B. Singleton, Daniele Cusi, John Hardy, Parastoo Momeni

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Overexpression of TREM2 enhances glioma cell proliferation and invasion: a therapeutic target in human glioma per Xiaoqiang Wang, Bangbao Tao, Bin Li, Xuhui Wang, Wenchuan Zhang, Liang Wan, Xuming Hua, Shiting Li

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Disease‐Associated Mutations of <scp>TREM2</scp> Alter the Processing of N‐Linked Oligosaccharides in the Golgi Apparatus per Ji‐Seon Park, In Jung Ji, Hyun Joo An, Min‐Ji Kang, Sang‐Wook Kang, Dong‐Hou Kim, Seung‐Yong Yoon

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<scp>TREM</scp>2 Protein Expression Changes Correlate with <scp>A</scp>lzheimer's Disease Neurodegenerative Pathologies in Post‐Mortem Temporal Cortices per Lih‐Fen Lue, Christopher T. Schmitz, Geidy E. Serrano, Lucia I. Sue, Thomas G. Beach, Douglas G. Walker

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R47H Variant of<i>TREM2</i>Associated With Alzheimer Disease in a Large Late-Onset Family per Olena Korvatska, James B. Leverenz, Suman Jayadev, Pamela J. McMillan, Irina Kurtz, Xindi Guo, Malia Rumbaugh, Mark Matsushita, Santhosh Girirajan, Michael O. Dorschner, Kostantin Kiianitsa, Chang-En Yu, Zoran Brkanac, Gwenn A. Garden, Wendy H. Raskind, Thomas D. Bird

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Developmental Regulation of TREM2 and DAP12 Expression in the Murine CNS: Implications for Nasu-Hakola Disease per J. Cameron Thrash, Bruce E. Torbett, Monica J. Carson

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TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease per Min Song, Jingji Jin, Jeong-Eun Lim, Jinghong Kou, Abhinandan Pattanayak, Jamaal Rehman, Hong‐Duck Kim, Kazuki Tahara, Robert Lalonde, Ken-ichiro Fukuchi

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Late-Onset Alzheimer’s Disease Genes and the Potentially Implicated Pathways per Samantha L. Rosenthal, M. Ilyas Kamboh

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<i>R47H TREM2</i> variant increases risk of typical early‐onset Alzheimer's disease but not of prion or frontotemporal dementia per Catherine F. Slattery, Jonathan Beck, Lorna Harper, Gary Adamson, Zeinab Abdi, James Uphill, Tracy Campbell, Ron Druyeh, Colin Mahoney, Jonathan D. Rohrer, Joanna Kenny, Jessica Lowe, Kelvin K. Leung, Josephine Barnes, Shona Clegg, Melanie Blair, Jennifer M. Nicholas, Rita Guerreiro, James B. Rowe, Claudia Ponto, Inga Zerr, Hans A. Kretzschmar, Pierluigi Gambetti, Sebastian J. Crutch, Jason D. Warren, Martin N. Rossor, Nick C. Fox, John Collinge, Jonathan M. Schott, Simon Mead

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A Comprehensive Profile of ChIP-Seq-Based PU.1/Spi1 Target Genes in Microglia per Jun‐ichi Satoh, Naohiro Asahina, Shouta Kitano, Yoshihiro Kino

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Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia per Elise Cuyvers, Karolien Bettens, Stéphanie Philtjens, Tim Van Langenhove, Ilse Gijselinck, Julie van der Zee, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Jasper Van Dongen, Nathalie Geerts, Githa Maes, Maria Mattheijssens, Karin Peeters, Patrick Cras, Rik Vandenberghe, Peter P. De Deyn, Christine Van Broeckhoven, Marc Cruts, Kristel Sleegers

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The genetics of Alzheimer&amp;#39;s disease per Eva Bagyinszky, Young Chul Youn, Seong Soo A. An, SangYun Kim

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Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a per Yuhai Zhao, Surjyadipta Bhattacharjee, Brandon Jones, Prerna Dua, Peter N. Alexandrov, James M. Hill, Walter J. Lukiw

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