Search Results - James Inglese

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  1. 1
    The Increasing Urgency for Standards in Basic Biologic Research

    The Increasing Urgency for Standards in Basic Biologic Research by Leonard P. Freedman, James Inglese

    Published 2014
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  2. 2
    Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology

    Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology by Natasha Thorne, James Inglese, Douglas S. Auld

    Published 2010
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  3. 3
    Apparent activity in high-throughput screening: origins of compound-dependent assay interference

    Apparent activity in high-throughput screening: origins of compound-dependent assay interference by Natasha Thorne, Douglas S. Auld, James Inglese

    Published 2010
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  4. 4
    Mitigating risk in academic preclinical drug discovery

    Mitigating risk in academic preclinical drug discovery by Jayme L. Dahlin, James Inglese, Michael A. Walters

    Published 2015
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  5. 5
    A Specific Mechanism for Nonspecific Activation in Reporter-Gene Assays

    A Specific Mechanism for Nonspecific Activation in Reporter-Gene Assays by Douglas S. Auld, Natasha Thorne, Ðắc-Trung Nguyễn, James Inglese

    Published 2008
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  6. 6
    Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression

    Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression by Douglas S. Auld, Natasha Thorne, William F. Maguire, James Inglese

    Published 2009
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  7. 7
    Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases.

    Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases. by Richard T. Premont, Walter J. Koch, James Inglese, Robert J. Lefkowitz

    Published 1994
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  8. 8
    Structure and mechanism of the G protein-coupled receptor kinases.

    Structure and mechanism of the G protein-coupled receptor kinases. by James Inglese, Neil J. Freedman, Walter J. Koch, Robert J. Lefkowitz

    Published 1993
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  9. 9
    The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.

    The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. by Walter J. Koch, James Inglese, W. Carl Stone, Robert J. Lefkowitz

    Published 1993
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  10. 10
    Binding of G protein beta gamma-subunits to pleckstrin homology domains.

    Binding of G protein beta gamma-subunits to pleckstrin homology domains. by Kazushige Touhara, James Inglese, J Pitcher, Gerry Shaw, Robert J. Lefkowitz

    Published 1994
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  11. 11
    Ca2+-dependent Interaction of Recoverin with Rhodopsin Kinase

    Ca2+-dependent Interaction of Recoverin with Rhodopsin Kinase by Ching-Kang Chen, James Inglese, Robert J. Lefkowitz, James B. Hurley

    Published 1995
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  12. 12
    Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family.

    Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family. by Robert H. Stoffel, R R Randall, Richard T. Premont, Robert J. Lefkowitz, James Inglese

    Published 1994
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  13. 13
    Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase.

    Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase. by James Inglese, J. Fraser Glickman, W Lorenz, Marc G. Caron, Robert J. Lefkowitz

    Published 1992
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  14. 14
    Identification of Drug Modulators Targeting Gene-Dosage Disease CMT1A

    Identification of Drug Modulators Targeting Gene-Dosage Disease CMT1A by Sung‐Wook Jang, Camila Lopez‐Anido, Ryan MacArthur, John Svaren, James Inglese

    Published 2012
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  15. 15
    Differentiating Alzheimer disease-associated aggregates with small molecules

    Differentiating Alzheimer disease-associated aggregates with small molecules by Nicolette S. Honson, Ronald L. Johnson, Wenwei Huang, James Inglese, Christopher P. Austin, Jeff Kuret

    Published 2007
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  16. 16
    Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a Reporter

    Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a Reporter by Natasha Thorne, Min Shen, Wendy Lea, Anton Simeonov, Scott Lovell, Douglas S. Auld, James Inglese

    Published 2012
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  17. 17
    Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.

    Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. by Walter J. Koch, Brian E. Hawes, James Inglese, Louis M. Luttrell, Robert J. Lefkowitz

    Published 1994
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  18. 18
    Olfactory desensitization requires membrane targeting of receptor kinase mediated by beta gamma-subunits of heterotrimeric G proteins.

    Olfactory desensitization requires membrane targeting of receptor kinase mediated by beta gamma-subunits of heterotrimeric G proteins. by Ingrid Boekhoff, James Inglese, Sabine Schleicher, Walter J. Koch, Robert J. Lefkowitz, Heinz Breer

    Published 1994
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  19. 19
    The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.

    The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase. by W Lorenz, James Inglese, Krzysztof Palczewski, James J. Onorato, Marc G. Caron, Robert J. Lefkowitz

    Published 1991
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  20. 20
    Identification of oxadiazoles as new drug leads for the control of schistosomiasis

    Identification of oxadiazoles as new drug leads for the control of schistosomiasis by Ahmed A. Sayed, Anton Simeonov, Craig J. Thomas, James Inglese, Christopher P. Austin, David L. Williams

    Published 2008
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