Search Results - Jaime H. Cheah

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  1. 1
    NMDA Receptor-Nitric Oxide Transmission Mediates Neuronal Iron Homeostasis via the GTPase Dexras1

    NMDA Receptor-Nitric Oxide Transmission Mediates Neuronal Iron Homeostasis via the GTPase Dexras1 by Jaime H. Cheah, Sangwon F. Kim, Lynda D. Hester, Kathleen Clancy, Stanley E. Patterson, Vassilios Papadopoulos, Solomon H. Snyder

    Published 2006
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  2. 2
    High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming

    High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming by Guangan Hu, Yang Su, Byong H. Kang, Zhongqi Fan, Ting Dong, Douglas Brown, Jaime H. Cheah, K. Dane Wittrup, Jianzhu Chen

    Published 2021
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  3. 3
    Dexras1, a Small GTPase, Is Required for Glutamate-NMDA Neurotoxicity

    Dexras1, a Small GTPase, Is Required for Glutamate-NMDA Neurotoxicity by Yong Chen, Reas S. Khan, Alyssa Cwanger, Ying Song, Catherine Steenstra, Sookhee Bang, Jaime H. Cheah, Joshua L. Dunaief, Kenneth S. Shindler, Solomon H. Snyder, Sangwon F. Kim

    Published 2013
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  4. 4
    S-Nitrosylation of N-Ethylmaleimide Sensitive Factor Mediates Surface Expression of AMPA Receptors

    S-Nitrosylation of N-Ethylmaleimide Sensitive Factor Mediates Surface Expression of AMPA Receptors by Yunfei Huang, Heng‐Ye Man, Yoko Sekine‐Aizawa, Yefei Han, Krishna R. Juluri, Hongbo R. Luo, Jaime H. Cheah, Charles J. Lowenstein, Richard L. Huganir, Solomon H. Snyder

    Published 2005
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  5. 5
    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes

    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes by Drew Adams, Daisuke Ito, Matthew G. Rees, Brinton Seashore‐Ludlow, Xiaoling Puyang, Alex H. Ramos, Jaime H. Cheah, Paul A. Clemons, Markus Warmuth, Ping Zhu, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2014
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  6. 6
    Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

    Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure by Sakie Katsumura, Nadeem Siddiqui, Michael R. Goldsmith, Jaime H. Cheah, Teppei Fujikawa, Genki Minegishi, Atsushi Yamagata, Yukako Yabuki, Kaoru Kobayashi, Mikako Shirouzu, Takeshi Inagaki, Tim H-M. Huang, Nicolas Musi, Ivan Topisirović, Ola Larsson, Masahiro Morita

    Published 2022
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  7. 7
    Regulation of Ferroptotic Cancer Cell Death by GPX4

    Regulation of Ferroptotic Cancer Cell Death by GPX4 by Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch, Kaoru Shimada, Rachid Skouta, Vasanthi S. Viswanathan, Jaime H. Cheah, Paul A. Clemons, Alykhan F. Shamji, Clary B. Clish, Lewis M. Brown, Albert W. Girotti, Virginia W. Cornish, Stuart L. Schreiber, Brent R. Stockwell

    Published 2014
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  8. 8
    Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

    Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes by Jessica Ewald, Katherine Titterton, Alex Bäuerle, Alex Beatson, Daniil A Boiko, Ángel Alexander Cabrera, Jaime H. Cheah, Beth A. Cimini, Bram L. Gorissen, Thouis R. Jones, Jakub Karczewski, David Rouquié, Srijit Seal, Erin Weisbart, Brandon M. White, Anne E. Carpenter, Shantanu Singh

    Published 2025
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  9. 9
    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery by Natalie Boehnke, Joelle P. Straehla, Hannah C. Safford, Mustafa Kocak, Matthew G. Rees, Melissa M. Ronan, Danny Rosenberg, Charles H. Adelmann, Raghu R. Chivukula, Namita Nabar, Adam G. Berger, Nicholas G. Lamson, Jaime H. Cheah, Hojun Li, Jennifer A. Roth, Angela N. Koehler, Paula T. Hammond

    Published 2022
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  10. 10
    A genetic basis for the variation in the vulnerability of cancer to DNA damage

    A genetic basis for the variation in the vulnerability of cancer to DNA damage by Brian D. Yard, Drew Adams, Eui Kyu Chie, Pablo Tamayo, Jessica Battaglia, Priyanka Gopal, Kevin Rogacki, Bradley Pearson, James G. Phillips, Daniel P. Raymond, Nathan A. Pennell, Francisco A. Almeida, Jaime H. Cheah, Paul A. Clemons, Alykhan F. Shamji, Craig D. Peacock, Stuart L. Schreiber, Peter S. Hammerman, Mohamed E. Abazeed

    Published 2016
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  11. 11
    Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics

    Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics by Gary W. Liu, Matthew J. Pickett, Johannes Kuosmanen, Keiko Ishida, Wiam Abdalla Mohammed Madani, Georgia N. White, J. A. Jenkins, Sanghyun Park, Vivian R. Feig, Miguel Jiménez, Christina Karavasili, Nikhil B. Lal, Matt Murphy, Aaron Lopes, Joshua Morimoto, Nina Fitzgerald, Jaime H. Cheah, Christian K. Soule, Niora Fabian, Alison Hayward, Róbert Langer, Giovanni Traverso

    Published 2024
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  12. 12
    Scalable, compressed phenotypic screening using pooled perturbations

    Scalable, compressed phenotypic screening using pooled perturbations by Nuo Liu, Walaa E. Kattan, Benjamin E. Mead, Conner Kummerlowe, Thomas W. Cheng, Sarah Ingabire, Jaime H. Cheah, Christian K. Soule, Anita Vrcic, Jane K. McIninch, Sergio Triana, Manuel Guzmán, Tyler T. Dao, Joshua M. Peters, Kristen E. Lowder, Lorin Crawford, Ava P. Amini, Paul C. Blainey, William C. Hahn, Brian Cleary, Bryan D. Bryson, Peter Winter, Srivatsan Raghavan, Alex K. Shalek

    Published 2024
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  13. 13
    Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset

    Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset by Brinton Seashore‐Ludlow, Matthew G. Rees, Jaime H. Cheah, Murat Cokol, Edmund V. Price, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Joshua Gould, Benjamin Alexander, Ava Li, Philip Montgomery, Mathias J. Wawer, Nurdan Kuru, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Joshua A. Bittker, Michelle Palmer, James E. Bradner, Alykhan F. Shamji, Paul A. Clemons, Stuart L. Schreiber

    Published 2015
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  14. 14
    Correlating chemical sensitivity and basal gene expression reveals mechanism of action

    Correlating chemical sensitivity and basal gene expression reveals mechanism of action by Matthew G. Rees, Brinton Seashore‐Ludlow, Jaime H. Cheah, Drew Adams, Edmund V. Price, Shubhroz Gill, Sarah Javaid, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Benjamin Alexander, Ava Li, Philip Montgomery, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Daniel A. Haber, Clary B. Clish, Joshua A. Bittker, Michelle Palmer, Bridget K. Wagner, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2015
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  15. 15
    An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

    An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules by Amrita Basu, Nicole E. Bodycombe, Jaime H. Cheah, Edmund V. Price, Ke Liu, Giannina I. Schaefer, Richard Y. Ebright, Michelle L. Stewart, Daisuke Ito, Stephanie Wang, Abigail Bracha, Ted Liefeld, Mathias J. Wawer, Joshua C. Gilbert, Andrew J. Wilson, Nicolas Stransky, Gregory V. Kryukov, Vlado Dančík, Jordi Barretina, Levi A. Garraway, C. Suk-Yee Hon, Benito Muñoz, Joshua A. Bittker, Brent R. Stockwell, Dineo Khabele, Andrew M. Stern, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2013
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  16. 16
    Integrated genetic and pharmacologic interrogation of rare cancers

    Integrated genetic and pharmacologic interrogation of rare cancers by Andrew L. Hong, Yuen‐Yi Tseng, Glenn S. Cowley, Oliver Jonas, Jaime H. Cheah, Bryan D. Kynnap, Mihir B. Doshi, Coyin Oh, Stephanie C. Meyer, Alanna J. Church, Shubhroz Gill, Craig M. Bielski, Paula Keskula, Alma Imamović, Sara Howell, Gregory V. Kryukov, Paul A. Clemons, Aviad Tsherniak, Francisca Vázquez, Brian D. Crompton, Alykhan F. Shamji, Carlos Rodríguez‐Galindo, Katherine A. Janeway, Charles W.M. Roberts, Kimberly Stegmaier, Paul Van Hummelen, Michael J. Cima, Róbert Langer, Levi A. Garraway, Stuart L. Schreiber, David E. Root, William C. Hahn, Jesse S. Boehm

    Published 2016
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  17. 17
    Screening in serum-derived medium reveals differential response to compounds targeting metabolism

    Screening in serum-derived medium reveals differential response to compounds targeting metabolism by Keene L. Abbott, Ahmed Ali, Dominick Casalena, T. Brian, Raphaël Ferreira, Jaime H. Cheah, Christian K. Soule, Amy Deik, Tenzin Kunchok, Daniel R. Schmidt, Steffen Renner, Sophie Honeder, Michelle Xiao Wu, Sze Ham Chan, Tenzin Tseyang, Andrew T. Stoltzfus, Sarah L. J. Michel, Daniel Greaves, Peggy P. Hsu, Christopher Ng, Chelsea J. Zhang, Ali Farsidjani, Johnathan R. Kent, Maria Lucia L. Madariaga, Iva Monique T. Gramatikov, Nicholas J. Matheson, Caroline A. Lewis, Clary B. Clish, Matthew G. Rees, Jennifer A. Roth, Lesley A. Mathews Griner, Alexander Muir, Douglas S. Auld, Matthew G. Vander Heiden

    Published 2023
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