检索结果 - Erwei Zuo

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  1. 1
    The Potential of CRISPR/Cas9 Gene Editing as a Treatment Strategy for Inherited Diseases

    The Potential of CRISPR/Cas9 Gene Editing as a Treatment Strategy for Inherited Diseases 由 Sameh A. Abdelnour, Long Xie, Abdallah A. Hassanin, Erwei Zuo, Yangqing Lu

    出版 2021
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    Revisão
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  2. 2
    Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

    Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos 由 Erwei Zuo, Yidi Sun, Wei Wu, Tanglong Yuan, Wenqin Ying, Hao Sun, Liyun Yuan, Lars M. Steinmetz, Yixue Li, Hui Yang

    出版 2019
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  3. 3
    Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos

    Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos 由 Yinghui Wei, Zhifang Li, Kui Xu, Feng Hu, Long Xie, Di Li, Zhenrui Zuo, Meiling Zhang, Chunlong Xu, Hui Yang, Erwei Zuo

    出版 2022
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  4. 4
    Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints

    Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints 由 Qinchang Chen, Guohui Chuai, Haihang Zhang, Jin Tang, Liwen Duan, Huan Guan, Wenhui Li, Wannian Li, Jiaying Wen, Erwei Zuo, Qing Zhang, Qi Liu

    出版 2023
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    Artigo
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  5. 5
    Structure-guided discovery of highly efficient cytidine deaminases with sequence-context independence

    Structure-guided discovery of highly efficient cytidine deaminases with sequence-context independence 由 Kui Xu, Feng Hu, Haihang Zhang, Chenfei He, Huifang Kang, Tanglong Yuan, Lei Shi, Chikai Zhou, Guoying Hua, Yaqi Cao, Zhenrui Zuo, Erwei Zuo

    出版 2024
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  6. 6
    Human cleaving embryos enable efficient mitochondrial base-editing with DdCBE

    Human cleaving embryos enable efficient mitochondrial base-editing with DdCBE 由 Yinghui Wei, Chunlong Xu, Feng Hu, Kui Xu, Zhifang Li, Jing Hu, Ling Zhou, Wei Yu, Zhenrui Zuo, Erwei Zuo, Li Wen, Hui Yang, Meiling Zhang

    出版 2022
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  7. 7
    Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects

    Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects 由 Sangsin Lee, Ning Ding, Yidi Sun, Tanglong Yuan, Jing Li, Qichen Yuan, Lizhong Liu, Jie Yang, Qian Wang, Anatoly B. Kolomeisky, Isaac B. Hilton, Erwei Zuo, Xue Gao

    出版 2020
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  8. 8
    Programmable C‐to‐U<scp>RNA</scp>editing using the human<scp>APOBEC</scp>3A deaminase

    Programmable C‐to‐U<scp>RNA</scp>editing using the human<scp>APOBEC</scp>3A deaminase 由 Xinxin Huang, Junjun Lv, Yongqin Li, Shaoshuai Mao, Zhifang Li, Zhengyu Jing, Yidi Sun, Xiaoming Zhang, Shengxi Shen, Xin Wang, Minghui Di, Jianyang Ge, Xingxu Huang, Erwei Zuo, Tian Chi

    出版 2020
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  9. 9
    Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice

    Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice 由 Nana Yan, Feng Hu, Yongsen Sun, Ying Xin, Haihang Zhang, Hongjiang Lu, Jitan Zheng, Chenfei He, Zhenrui Zuo, Tanglong Yuan, Nana Li, Long Xie, Wei Wu, Yidi Sun, Erwei Zuo

    出版 2023
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  10. 10
    Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods

    Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods 由 Tanglong Yuan, Nana Yan, Tianyi Fei, Jitan Zheng, Juan Meng, Nana Li, Jing Liu, Haihang Zhang, Long Xie, Wenqin Ying, Di Li, Lei Shi, Yongsen Sun, Yongyao Li, Yixue Li, Yidi Sun, Erwei Zuo

    出版 2021
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  11. 11
    Mini-dCas13X–mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy

    Mini-dCas13X–mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy 由 Guoling Li, Ming Jin, Zhifang Li, Qingquan Xiao, Jiajia Lin, Dong Yang, Yuanhua Liu, Xing Wang, Long Xie, Wenqin Ying, Haoqiang Wang, Erwei Zuo, Linyu Shi, Ning Wang, Wan‐Jin Chen, Chunlong Xu, Hui Yang

    出版 2022
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  12. 12
    CRISPR/Cas9-mediated targeted chromosome elimination

    CRISPR/Cas9-mediated targeted chromosome elimination 由 Erwei Zuo, Xiaona Huo, Xuan Yao, Xinde Hu, Yidi Sun, Jianhang Yin, Bingbing He, Xing Wang, Linyu Shi, Jie Ping, Wei Yu, Wenqin Ying, Wei Wei, Wenjia Liu, Cheng Tang, Yixue Li, Jiazhi Hu, Hui Yang

    出版 2017
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  13. 13
    Gene editing in a Myo6 semi-dominant mouse model rescues auditory function

    Gene editing in a Myo6 semi-dominant mouse model rescues auditory function 由 Yuanyuan Xue, Xinde Hu, Daqi Wang, Di Li, Yige Li, Fang Wang, Mingqian Huang, Xi Gu, Zhijiao Xu, Jinan Zhou, Jinghan Wang, Renjie Chai, Jun Shen, Zheng‐Yi Chen, Geng‐Lin Li, Hui Yang, Huawei Li, Erwei Zuo, Yilai Shu

    出版 2021
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  14. 14
    Discovery of deaminase functions by structure-based protein clustering

    Discovery of deaminase functions by structure-based protein clustering 由 Jiaying Huang, Qiupeng Lin, Hongyuan Fei, Zixin He, Hu Xu, Yunjia Li, Kunli Qu, Peng Han, Qiang Gao, Boshu Li, Guanwen Liu, Lixiao Zhang, Jiacheng Hu, Rui Zhang, Erwei Zuo, Yonglun Luo, Yidong Ran, Jin‐Long Qiu, Kevin T. Zhao, Caixia Gao

    出版 2023
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  15. 15
    Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes

    Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes 由 Tanglong Yuan, Leilei Wu, Shiyan Li, Jitan Zheng, Nana Li, Xiao Xiao, Haihang Zhang, Tianyi Fei, Long Xie, Zhenrui Zuo, Di Li, Pinzheng Huang, Feng Hu, Yaqi Cao, Nana Yan, Xinming Wei, Lei Shi, Yongsen Sun, Wei Wu, Yidi Sun, Erwei Zuo

    出版 2024
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  16. 16
    PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis

    PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis 由 Xiukun Wang, Jun-Yan Kang, Leixin Wei, Xiaogan Yang, Hongduo Sun, Suming Yang, Lei Lü, Meng Yan, Meizhu Bai, Yanyan Chen, Juanjuan Long, Na Li, Dangsheng Li, Jing Huang, Ming Lei, Zhen Shao, Yuan Wen, Erwei Zuo, LU Ke-huan, Mo‐Fang Liu, Jinsong Li

    出版 2019
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  17. 17
    CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development

    CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development 由 Lingbo Wang, Min-Yin Li, Chao Qu, Wanying Miao, Qi Yin, Jiaoyang Liao, Hua-Teng Cao, Min Huang, Kai Wang, Erwei Zuo, Guangdun Peng, Shu-Xin Zhang, Guodong Chen, Qing Li, Ke Tang, Yu Qian, Zhoujie Li, Catherine C. L. Wong, Guoliang Xu, Naihe Jing, Xiang Yu, Jinsong Li

    出版 2017
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  18. 18
    One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

    One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs 由 Erwei Zuo, Yijun Cai, Kui Li, Wei Yu, Bang-An Wang, Yidi Sun, Zhen Liu, Jiwei Liu, Xinde Hu, Wei Wei, Xiaona Huo, Linyu Shi, Cheng Tang, Dan Liang, Yan Wang, Yanhong Nie, Chenchen Zhang, Xuan Yao, Xing Wang, Changyang Zhou, Wenqin Ying, Qifang Wang, Renchao Chen, Qi Shen, Guoliang Xu, Jinsong Li, Qiang Sun, Zhi‐Qi Xiong, Hui Yang

    出版 2017
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  19. 19
    Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

    Loss of function of CMPK2 causes mitochondria deficiency and brain calcification 由 Miao Zhao, Hui‐Zhen Su, Yi‐Heng Zeng, Yuan Sun, Xinxin Guo, Yun‐Lu Li, Chong Wang, Zhiyuan Zhao, Xue-Jing Huang, Kai-Jun Lin, Zi-Ling Ye, Bi-Wei Lin, Shunyan Hong, Jitan Zheng, Yaobin Liu, Xiang‐Ping Yao, Dehao Yang, Ying‐Qian Lu, Hai‐Zhu Chen, Erwei Zuo, Guang Yang, Hongtao Wang, Chen‐Wei Huang, Xiao-Hong Lin, Zhidong Cen, Lu‐Lu Lai, Yan-Ke Zhang, Xi Li, Tianmin Lai, Jingjing Lin, Dandan Zuo, Min‐Ting Lin, Chia‐Wei Liou, Qingxia Kong, Chuanzhu Yan, Zhi‐Qi Xiong, Ning Wang, Wei Luo, Cuiping Zhao, Xuewen Cheng, Wan‐Jin Chen

    出版 2022
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  20. 20
    Novel Genetic Loci Affecting Facial Shape Variation in Humans

    Novel Genetic Loci Affecting Facial Shape Variation in Humans 由 Ziyi Xiong, Haibo Zhou, Gabriela Dankova, Laurence J Howe, Myoung Keun Lee, Pirro G. Hysi, Markus A. de Jong, Gu Zhu, Kaustubh Adhikari, Dan Li, Yi Li, Li He, Bo Pan, Eleanor Feingold, Mary L. Marazita, John R. Shaffer, Kerrie McAloney, Shuhua Xu, Jin Li, Sijia Wang, Femke M.S. de Vrij, Bas Lendemeijer, Stephen Richmond, Alexei I. Zhurov, Erwei Zuo, Sarah J. Lewis, Gemma C. Sharp, Lavinia Paternoster, Holly Thompson, Rolando González‐José, María Cátira Bortolini, Samuel Canizales‐Quinteros, Carla Gallo, Giovanni Poletti, Gabriel Bedoya, Francisco Rothhammer, André G. Uitterlinden, M. Arfan Ikram, Eppo B. Wolvius, Steven A. Kushner, Tamar Nijsten, Robert‐Jan Palstra, Stefan Böehringer, Sarah E. Medland, Kun Tang, Andrés Ruiz‐Linares, Nicholas G. Martin, Hui Yang, Timothy D. Spector, Evie Stergiakouli, Seth M. Weinberg, Fan Liu, Manfred Kayser

    出版 2018
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