نتائج البحث

Efficient CRISPR/Cas9-mediated biallelic gene disruption and site-specific knockin after rapid selection of highly active sgRNAs in pigs حسب Xianlong Wang, Jinwei Zhou, Chunwei Cao, Jiaojiao Huang, Tang Hai, Yanfang Wang, Qiantao Zheng, Hongyong Zhang, Guosong Qin, Xiangnan Miao, Hongmei Wang, Suizhong Cao, Qi Zhou, Jianguo Zhao

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Transcriptome-wide dynamics of RNA pseudouridylation حسب John Karijolich, Chengqi Yi, Yi‐Tao Yu

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Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication حسب Jie Wang

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Rapid and efficient one-step generation of paired gRNA CRISPR-Cas9 libraries حسب Joana A. Vidigal, Andrea Ventura

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Precise Gene Deletion and Replacement Using the CRISPR/Cas9 System in Human Cells حسب Qiupeng Zheng, Xiaohong Cai, Meng How Tan, Steven Schaffert, Christopher P. Arnold, Xue Gong, Changzheng Chen, Shenglin Huang

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Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display حسب David M. Shechner, Ezgi Hacisuleyman, Scott T. Younger, John L. Rinn

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Mechanism of CRISPR-RNA guided recognition of DNA targets in<i>Escherichia coli</i> حسب Paul B. G. van Erp, Ryan N. Jackson, Joshua Carter, Sarah Golden, Scott Bailey, Blake Wiedenheft

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Enriching CRISPR-Cas9 targeted cells by co-targeting the HPRT gene حسب Shuren Liao, Margaret Tammaro, Hong Yan

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Self‐processing of ribozyme‐flanked RNAs into guide RNAs <i>in vitro</i> and <i>in vivo</i> for CRISPR‐mediated genome editing حسب Yangbin Gao, Yunde Zhao

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Off‐target assessment of <scp>CRISPR</scp>‐<scp>C</scp>as9 guiding <scp>RNA</scp>s in human i<scp>PS</scp> and mouse <scp>ES</scp> cells حسب E‐Pien Tan, Yilong Li, Martin Del Castillo Velasco‐Herrera, Kosuke Yusa, Allan Bradley

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Origins of Programmable Nucleases for Genome Engineering حسب Srinivasan Chandrasegaran, Dana Carroll

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Cas9 gRNA engineering for genome editing, activation and repression حسب Samira Kiani, Alejandro Chavez, Marcelle Tuttle, Richard Hall, Raj Chari, Dmitry Ter‐Ovanesyan, Jason Qian, Benjamin W. Pruitt, Jacob Beal, Suhani Vora, Joanna Buchthal, Emma J. K. Kowal, Mo R. Ebrahimkhani, James J. Collins, Ron Weiss, George M. Church

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CRISPR-STAT: an easy and reliable PCR-based method to evaluate target-specific sgRNA activity حسب Blake Carrington, Gaurav K. Varshney, Shawn M. Burgess, Raman Sood

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Efficient genomic correction methods in human iPS cells using CRISPR–Cas9 system حسب Hongmei Lisa Li, Peter Gee, Kentaro Ishida, Akitsu Hotta

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Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region حسب Scott J Westenberger, Gustavo C. Cerqueira, Najib M. El-Sayed, Bianca Zingales, David A. Campbell, Nancy R. Sturm

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Genome Engineering Using CRISPR-Cas9 System حسب Le Cong, Feng Zhang

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Advances in therapeutic CRISPR/Cas9 genome editing حسب Nataša Savić, Gerald Schwank

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Cloning-free CRISPR حسب Mandana Arbab, Sharanya Srinivasan, Tatsunori Hashimoto, Niels Geijsen, Richard I. Sherwood

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Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing حسب Nicolas Wyvekens, Ved V. Topkar, Cyd Khayter, J. Keith Joung, Shengdar Q. Tsai

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Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach حسب Raj Chari, Prashant Mali, Mark Moosburner, George M. Church

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