Ngā hua rapu - Diego Sepúlveda‐Falla

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  1. 1
    Cerebral Small Vessel Disease in Sporadic and Familial Alzheimer Disease

    Cerebral Small Vessel Disease in Sporadic and Familial Alzheimer Disease mā Rajesh N. Kalaria, Diego Sepúlveda‐Falla

    I whakaputaina 2021
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    Revisão
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  2. 2
    Genetic modifiers of cognitive decline in <i>PSEN1</i> E280A Alzheimer's disease

    Genetic modifiers of cognitive decline in <i>PSEN1</i> E280A Alzheimer's disease mā Diego Sepúlveda‐Falla, Jorge I. Vélez, Natalia Acosta‐Baena, Ana Baena, Sonia Moreno, Susanne Krasemann, Francisco Lopera, Claudio A. Mastronardi, Mauricio Arcos‐Burgos

    I whakaputaina 2024
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  3. 3
    Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia

    Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia mā A. Hartmann, Diego Sepúlveda‐Falla, Indigo V.L. Rose, Charlotte Madore, Christiane Muth, Jakob Matschke, Oleg Butovsky, Shane A. Liddelow, Markus Glatzel, Susanne Krasemann

    I whakaputaina 2019
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  4. 4
    Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease

    Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease mā Diego Sepúlveda‐Falla, Jakob Matschke, Christian Bernreuther, Christian Hagel, Berta Puig, Andrés Villegas, Gloria García, Julián Zea Lopera, Baltazar Gomez‐Mancilla, Isidró Ferrer, Francisco Lopera, Markus Glatzel

    I whakaputaina 2010
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  5. 5
    Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease

    Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease mā María Szaruga, Sarah Veugelen, Manasi Benurwar, Sam Lismont, Diego Sepúlveda‐Falla, Alberto Lleó, Natalie S. Ryan, Tammaryn Lashley, Nick C. Fox, Shigeo Murayama, Harrie J. M. Gijsen, Bart De Strooper, Lucía Chávez‐Gutiérrez

    I whakaputaina 2015
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  6. 6
    Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease

    Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease mā Marta Pera, Daniel Alcolea, Raquel Sánchez‐Valle, Cristina Guardia‐Laguarta, Martí Colom‐Cadena, Nahuai Badiola, Marc Suárez‐Calvet, Albert Lladó, Álvaro Barrera-Ocampo, Diego Sepúlveda‐Falla, Rafael Blesa, José Luís Molinuevo, Jordi Clarimón, Isidró Ferrer, Ellen Gelpí, Alberto Lleó

    I whakaputaina 2012
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  7. 7
    A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease

    A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease mā Diego Sepúlveda‐Falla, Lucía Chávez‐Gutiérrez, Erik Portelius, Jorge I. Vélez, Simon Dujardin, Álvaro Barrera-Ocampo, Felix Dinkel, Christian Hagel, Berta Puig, Claudio A. Mastronardi, Francisco Lopera, Bradley T. Hyman, Kaj Blennow, Mauricio Arcos‐Burgos, Bart De Strooper, Markus Glatzel

    I whakaputaina 2020
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  8. 8
    Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis

    Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis mā Diego Sepúlveda‐Falla, Álvaro Barrera-Ocampo, Christian Hagel, Anne Korwitz, María Fernanda Vinueza‐Veloz, Kuikui Zhou, Martijn Schonewille, Haibo Zhou, Luis Velázquez‐Pérez, Roberto Rodríguez‐Labrada, Andrés Villegas, Isidró Ferrer, Francisco Lopera, Thomas Länger, Chris I. De Zeeuw, Markus Glatzel

    I whakaputaina 2014
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  9. 9
    APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer’s cases

    APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer’s cases mā Paula Perez‐Corredor, Timothy E. Vanderleest, Guido N. Vacano, Justin S. Sanchez, Nelson David Villalba‐Moreno, Claudia Mariño, Susanne Krasemann, Miguel Mendivil‐Perez, David Aguillón, Marlene Jiménez-Del-Río, Ana Baena, Diego Sepúlveda‐Falla, Francisco Lopera, Yakeel T. Quiroz, Joseph F. Arboleda‐Velásquez, Randall C. Mazzarino

    I whakaputaina 2024
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  10. 10
    Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease

    Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease mā Jay Rasmussen, Jasmin Mahler, Natalie Beschörner, Stephan A. Kaeser, Lisa M. Häsler, Frank Baumann, Sofie Nyström, Erik Portelius, Kaj Blennow, Tammaryn Lashley, Nick C. Fox, Diego Sepúlveda‐Falla, Markus Glatzel, Adrian L. Oblak, Bernardino Ghetti, K. Peter R. Nilsson, Per Hammarström, Matthias Staufenbiel, Lary C. Walker, Mathias Jucker

    I whakaputaina 2017
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  11. 11
    Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity

    Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity mā Yakeel T. Quiroz, David Aguillón, Joseph F. Arboleda‐Velásquez, Yamile Bocanegra, Gloria Patricia Cardona‐Gómez, María M. Corrada, Ibai Díez, Elkin Garcia‐Cifuentes, Kenneth S. Kosik, L. Martínez, David Antonio Pineda-Salazar, Rafael Posada, Norbel Román, Diego Sepúlveda‐Falla, Andrea Slachevsky, Marcio Soto‐Añari, Evelyn Tabilo, Daniel Vasquez, Andrés Villegas‐Lanau

    I whakaputaina 2025
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  12. 12
    Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

    Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders mā Sebastian Palmqvist, Shorena Janelidze, Yakeel T. Quiroz, Henrik Zetterberg, Francisco Lopera, Erik Stomrud, Yi Su, Yinghua Chen, Geidy E. Serrano, Antoine Leuzy, Niklas Mattsson, Olof Strandberg, Ruben Smith, Andrés Villegas, Diego Sepúlveda‐Falla, Xiyun Chai, Nicholas K. Proctor, Thomas G. Beach, Kaj Blennow, Jeffrey L. Dage, Eric M. Reiman, Oskar Hansson

    I whakaputaina 2020
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  13. 13
    Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer’s disease profile and possible mechanisms of disease protection

    Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer’s disease profile and possible mechanisms of disease protection mā Maria Camila Almeida, Sarah J. Eger, C. He, Morgane Audouard, Arina Nikitina, Stella M.K. Glasauer, Dasol Han, Bárbara Mejía‐Cupajita, Juliana Acosta‐Uribe, Nelson David Villalba‐Moreno, Jessica Lisa Littau, Megan Elcheikhali, Erica Keane Rivera, Daniel Carneiro Carrettiero, Carlos Andrés Villegas‐Lanau, Diego Sepúlveda‐Falla, Francisco Lopera, Kenneth S. Kosik

    I whakaputaina 2024
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  14. 14
    APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease

    APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease mā Jorge I. Vélez, Francisco Lopera, Diego Sepúlveda‐Falla, Hardip R. Patel, Angad Johar, Aaron Chuah, Carlos Tobón, Diego Rivera, Andrés Villegas, Yu Cai, Kun Peng, Ruth M. Arkell, F. Xavier Castellanos, Shea J. Andrews, M F Silva Lara, Penelope K. Creagh, Simon Easteal, José de León, Ma‐Li Wong, Júlio Licinio, Claudio A. Mastronardi, Mauricio Arcos‐Burgos

    I whakaputaina 2015
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  15. 15
    APOE Christchurch‐mimetic therapeutic antibody reduces APOE‐mediated toxicity and tau phosphorylation

    APOE Christchurch‐mimetic therapeutic antibody reduces APOE‐mediated toxicity and tau phosphorylation mā Claudia Mariño, Paula Perez‐Corredor, Michael O’Hare, Annie Heuer, Natalia Chmielewska, H Gordon, Anita Chandrahas, Lucía González-Buendía, Santiago Delgado‐Tirado, Tri Huu Doan, Timothy E. Vanderleest, Said Arévalo-Alquichire, Robert A. Obar, Carolina Ortiz‐Cordero, Andrés Villegas, Diego Sepúlveda‐Falla, Leo A. Kim, Francisco Lopera, Robert W. Mahley, Yadong Huang, Yakeel T. Quiroz, Joseph F. Arboleda‐Velásquez

    I whakaputaina 2023
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  16. 16
    Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study

    Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study mā Yakeel T. Quiroz, Henrik Zetterberg, Eric M. Reiman, Yinghua Chen, Yi Su, Joshua T. Fox‐Fuller, Gloria García, Andrés Villegas, Diego Sepúlveda‐Falla, Marina Villada, Joseph F. Arboleda‐Velásquez, Edmarie Guzmán‐Vélez, Clara Vila‐Castelar, Brian A. Gordon, Stephanie A. Schultz, Hillary Protas, Valentina Ghisays, Margarita Giraldo, Victoria Tirado, Ana Baena, Claudia Muñoz, Silvia Ríos‐Romenets, Pierre N. Tariot, Kaj Blennow, Francisco Lopera

    I whakaputaina 2020
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  17. 17
    Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia

    Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia mā Diego Sepúlveda‐Falla, Justin S. Sanchez, Maria Camila Almeida, Daniela Boassa, Juliana Acosta‐Uribe, Clara Vila‐Castelar, Liliana Ramı́rez-Gomez, Ana Baena, David Aguillón, Nelson David Villalba‐Moreno, Jessica Lisa Littau, Andrés Villegas, Thomas G. Beach, Charles L. White, Mark H. Ellisman, Susanne Krasemann, Markus Glatzel, Keith A. Johnson, Reisa A. Sperling, Eric M. Reiman, Joseph F. Arboleda‐Velásquez, Kenneth S. Kosik, Francisco Lopera, Yakeel T. Quiroz

    I whakaputaina 2022
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  18. 18
    The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

    The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2 mā Susanne Krasemann, Undine Haferkamp, Susanne Pfefferle, Marcel S. Woo, Fabian Heinrich, Michaela Schweizer, Antje Appelt‐Menzel, Alevtina Cubukova, Janica Barenberg, Jennifer Leu, Kristin Hartmann, Edda Thies, Jessica Lisa Littau, Diego Sepúlveda‐Falla, Liang Zhang, Kathy Ton, Yan Liang, Jakob Matschke, Franz Ricklefs, Thomas Sauvigny, Jan Sperhake, Antonia Fitzek, Anna Gerhartl, Andreas Brachner, Nina Geiger, Eva‐Maria König, Jochen Bodem, Sören Franzenburg, André Franke, Stefan Moese, Frank Müller, Gerd Geißlinger, Carsten Claussen, Aimo Kannt, Andrea Zaliani, Philip Gribbon, Benjamin Ondruschka, Winfried Neuhaus, Manuel A. Friese, Markus Glatzel, Ole Pleß

    I whakaputaina 2022
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  19. 19
    Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man

    Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man mā Francisco Lopera, Claudia Mariño, Anita Chandrahas, Michael O’Hare, Nelson David Villalba‐Moreno, David Aguillón, Ana Baena, Justin S. Sanchez, Clara Vila‐Castelar, Liliana Ramírez Gómez, Natalia Chmielewska, Gabriel Melo de Oliveira, Jessica Lisa Littau, A. Hartmann, Kyung-Eun Park, Susanne Krasemann, Markus Glatzel, Dorothée Schoemaker, Lucía González-Buendía, Santiago Delgado‐Tirado, Said Arévalo-Alquichire, Kahira L. Saez‐Torres, Dhanesh Amarnani, Leo A. Kim, Randall C. Mazzarino, H Gordon, Yamile Bocanegra, Andrés Villegas, Xiaowu Gai, Moiz Bootwalla, Jianling Ji, Li Shen, Kenneth S. Kosik, Yi Su, Yinghua Chen, Aaron P. Schultz, Reisa A. Sperling, Keith A. Johnson, Eric M. Reiman, Diego Sepúlveda‐Falla, Joseph F. Arboleda‐Velásquez, Yakeel T. Quiroz

    I whakaputaina 2023
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  20. 20
    The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact

    The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact mā Raj N. Kalaria, Gladys E. Maestre, Simin Mahinrad, Daisy M Acosta, Rufus Akinyemi, Suvarna Alladi, Ricardo Allegri, Faheem Arshad, David Oluwasayo Babalola, Olusegun Baiyewu, Thomas H. Bak, Tarek Bellaj, David K. Brodie‐Mends, Marı́a C. Carrillo, Kaputu‐Kalala‐Malu Celestin, Albertino Damasceno, Ranil Karunamuni de Silva, Rohan de Silva, Mamuka Djibuti, Anna J. Dreyer, Ratnavalli Ellajosyula, Temitope Farombi, Robert P. Friedland, Noe Garza, Antoine Gbessemehlan, Eliza Georgiou, Ishtar Govia, Lea T. Grinberg, Maëlenn Guerchet, Seid Ali Gugssa, Joy Louise Gumikiriza‐Onoria, Eef Hogervorst, Michael Hornberger, Agustín Ibáñez, Masafumi Ihara, Thomas Gregor Issac, Linus Jönsson, Wambui Karanja, Joseph H. Lee, Iracema Leroi, Gill Livingston, Facundo Manes, Lingani Mbakile‐Mahlanza, Bruce L. Miller, Christine Musyimi, Victoria Mutiso, Noeline Nakasujja, David M. Ndetei, Sam Nightingale, Gabriela Novotni, Primrose Nyamayaro, Solomon Nyame, Julius A Ogeng’o, Adesola Ogunniyi, Maira Okada de Oliveira, Njideka Okubadejo, Martin Orrell, Stella‐Maria Paddick, Margaret A. Pericak‐Vance, Zvezdan Pirtošek, Felix Potocnik, Rema Raman, Mie Rizig, Mónica Rosselli, M. Salokhiddinov, Claudia L. Satizábal, Diego Sepúlveda‐Falla, Sudha Seshadri, Claire E. Sexton, Ingmar Skoog, Peter St George‐Hyslop, Cláudia Kimie Suemoto, Prekshy Thapa, Chinedu Udeh‐Momoh, Victor Valcour, Jeffery M. Vance, Mathew Varghese, Jaime H. Vera, Richard Walker, Henrik Zetterberg, Yared Z. Zewde, Ozama Ismail

    I whakaputaina 2024
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