Resultados de procura - David Borchelt

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  1. 1
    Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states

    Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states por Mercedes Prudencio, David Borchelt

    Publicado 2011
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  2. 2
    A Limited Role for Disulfide Cross-linking in the Aggregation of Mutant SOD1 Linked to Familial Amyotrophic Lateral Sclerosis

    A Limited Role for Disulfide Cross-linking in the Aggregation of Mutant SOD1 Linked to Familial Amyotrophic Lateral Sclerosis por Celeste M. Karch, David Borchelt

    Publicado 2008
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  3. 3
    Mapping superoxide dismutase 1 domains of non‐native interaction: roles of intra‐ and intermolecular disulfide bonding in aggregation

    Mapping superoxide dismutase 1 domains of non‐native interaction: roles of intra‐ and intermolecular disulfide bonding in aggregation por Jiou Wang, Guilian Xu, David Borchelt

    Publicado 2006
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  4. 4
    Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease

    Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease por Tosha Williams, David Borchelt, Paramita Chakrabarty

    Publicado 2020
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  5. 5
    Evidence for synthesis of scrapie prion proteins in the endocytic pathway.

    Evidence for synthesis of scrapie prion proteins in the endocytic pathway. por David Borchelt, Albert Taraboulos, Stanley B. Prusiner

    Publicado 1992
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  6. 6
    Prion-like Spreading in Tauopathies

    Prion-like Spreading in Tauopathies por Jacob I. Ayers, Benoit I. Giasson, David Borchelt

    Publicado 2017
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  7. 7
    Synaptic Transmission and Hippocampal Long-Term Potentiation in Transgenic Mice Expressing FAD-Linked Presenilin 1

    Synaptic Transmission and Hippocampal Long-Term Potentiation in Transgenic Mice Expressing FAD-Linked Presenilin 1 por Angèle Parent, David J. Linden, Sangram S. Sisodia, David Borchelt

    Publicado 1999
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  8. 8
    Variation in aggregation propensities among ALS-associated variants of SOD1: Correlation to human disease

    Variation in aggregation propensities among ALS-associated variants of SOD1: Correlation to human disease por Mercedes Prudencio, Peter Hart, David Borchelt, Peter M. Andersen

    Publicado 2009
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  9. 9
    An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1

    An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1 por Mercedes Prudencio, Armando Durazo, Julian P. Whitelegge, David Borchelt

    Publicado 2010
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  10. 10
    Thinking laterally about neurodegenerative proteinopathies

    Thinking laterally about neurodegenerative proteinopathies por Todd E. Golde, David Borchelt, Benoit I. Giasson, Jada Lewis

    Publicado 2013
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  11. 11
    Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis

    Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis por Kim A. Staats, David Borchelt, Malú G. Tansey, James Wymer

    Publicado 2022
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  12. 12
    Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells.

    Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. por David Borchelt, Michael Scott, Albert Taraboulos, Neil Stahl, Stanley B. Prusiner

    Publicado 1990
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  13. 13
    Environmental Enrichment Exacerbates Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease

    Environmental Enrichment Exacerbates Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease por Joanna L. Jankowsky, Guilian Xu, David Fromholt, Victoria Gonzales, David Borchelt

    Publicado 2003
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  14. 14
    Alzheimer's-Type Amyloidosis in Transgenic Mice Impairs Survival of Newborn Neurons Derived from Adult Hippocampal Neurogenesis

    Alzheimer's-Type Amyloidosis in Transgenic Mice Impairs Survival of Newborn Neurons Derived from Adult Hippocampal Neurogenesis por Laure Verret, Joanna L. Jankowsky, G. M. Xu, David Borchelt, Claire Rampon

    Publicado 2007
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  15. 15
    Synthesis and trafficking of prion proteins in cultured cells.

    Synthesis and trafficking of prion proteins in cultured cells. por Albert Taraboulos, Alex J. Raeber, David Borchelt, D. Serban, Stanley B. Prusiner

    Publicado 1992
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  16. 16
    Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS

    Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS por Megan W. Bourassa, Hilda Brown, David Borchelt, Stefan Vogt, Lisa M. Miller

    Publicado 2014
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  17. 17
    Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

    Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways por Jacob I. Ayers, Susan Fromholt, Veronica O’Neal, Jeffrey Diamond, David Borchelt

    Publicado 2015
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  18. 18
    Characterization of Protein Structural Changes in Living Cells Using Time-Lapsed FTIR Imaging

    Characterization of Protein Structural Changes in Living Cells Using Time-Lapsed FTIR Imaging por Paul Gelfand, Randy J. Smith, Eli Stavitski, David Borchelt, Lisa M. Miller

    Publicado 2015
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  19. 19
    Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS

    Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS por Celeste M. Karch, Mercedes Prudencio, Duane D. Winkler, P. John Hart, David Borchelt

    Publicado 2009
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  20. 20
    Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis

    Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis por Guilian Xu, Stanley M. Stevens, Brenda D. Moore, Scott McClung, David Borchelt

    Publicado 2013
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