खोज परिणाम - Christopher B. Eckman
- प्रदर्शित 1 - 20 परिणाम 28
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Molecular Characterization of Mutations That Cause Globoid Cell Leukodystrophy and Pharmacological Rescue Using Small Molecule Chemical Chaperones द्वारा Chris W. Lee, Dongcheul Kang, Ena Causevic, Aimee Herdt, Elizabeth A. Eckman, Christopher B. Eckman
प्रकाशित 2010Artigo -
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γ-Secretase, Evidence for Multiple Proteolytic Activities and Influence of Membrane Positioning of Substrate on Generation of Amyloid β Peptides of Varying Length द्वारा M. Paul Murphy, Lesley Hickman, Christopher B. Eckman, Sacha N. Uljon, Rong Wang, Todd E. Golde
प्रकाशित 1999Artigo -
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Partial Loss-of-Function Mutations in Insulin-Degrading Enzyme that Induce Diabetes also Impair Degradation of Amyloid β-Protein द्वारा Wesley Farris, Stefan Mansourian, Malcolm A. Leissring, Elizabeth A. Eckman, Lars Bertram, Christopher B. Eckman, Rudolph E. Tanzi, Dennis J. Selkoe
प्रकाशित 2004Artigo -
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Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ<i>via</i>exosomes द्वारा Javier Pacheco‐Quinto, Dana M. Clausen, Rocío Pérez‐González, Hui Peng, Austin Meszaros, Christopher B. Eckman, Efrat Levy, Elizabeth A. Eckman
प्रकाशित 2018Artigo -
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A Novel γ-Secretase Assay Based on Detection of the Putative C-terminal Fragment-γ of Amyloid β Protein Precursor द्वारा Inga Pinnix, Usha Musunuru, Han W. Tun, Arati Sridharan, Todd E. Golde, Christopher B. Eckman, Chewki Ziani-Chérif, Luisa Onstead, Kumar Sambamurti
प्रकाशित 2001Artigo -
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Cellular prion protein regulates β-secretase cleavage of the Alzheimer's amyloid precursor protein द्वारा Edward T. Parkin, Nicole T. Watt, Ishrut Hussain, Elizabeth A. Eckman, Christopher B. Eckman, Jean Manson, Herbert Baybutt, Anthony J. Turner, Nigel M. Hooper
प्रकाशित 2007Artigo -
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Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme द्वारा Elizabeth A. Eckman, Stephanie K. Adams, Frederick J. Troendle, Becky A. Stodola, Murad A. Kahn, Abdul H. Fauq, Hong Xiao, Kenneth E. Bernstein, Christopher B. Eckman
प्रकाशित 2006Artigo -
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Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i> द्वारा Wesley Farris, Stefan Mansourian, Yang Chang, Loren Lindsley, Elizabeth A. Eckman, Matthew P. Frosch, Christopher B. Eckman, Rudolph E. Tanzi, Dennis J. Selkoe, Suzanne Y. Guénette
प्रकाशित 2003Artigo -
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Genetic Modification of the Phenotypes Produced by Amyloid Precursor Protein Overexpression in Transgenic Mice द्वारा George A. Carlson, David Borchelt, A. Dake, Sherry Turner, V. Danielson, J. Douglas Coffin, Christopher B. Eckman, Julia Meiners, Steven P. Nilsen, Steven G. Younkin, Karen Hsiao
प्रकाशित 1997Artigo -
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The ACAT Inhibitor CP-113,818 Markedly Reduces Amyloid Pathology in a Mouse Model of Alzheimer's Disease द्वारा Birgit Hutter‐Paier, Henri J. Huttunen, Luigi Puglielli, Christopher B. Eckman, Doo Yeon Kim, Alexander Hofmeister, Robert D. Moir, Sarah Domnitz, Matthew P. Frosch, Manfred Windisch, Dora M. Kovacs
प्रकाशित 2004Artigo -
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Discovery of a Novel Pharmacological and Structural Class of Gamma Secretase Modulators Derived from the Extract of Actaea racemosa द्वारा Mark A. Findeis, Frank C. Schroeder, Timothy D. McKee, Debra Yager, Patrick C. Fraering, Steffen P. Creaser, Wesley Austin, Jon Clardy, Rong Wang, Dennis J. Selkoe, Christopher B. Eckman
प्रकाशित 2012Artigo -
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The Secreted β-Amyloid Precursor Protein Ectodomain APPsα Is Sufficient to Rescue the Anatomical, Behavioral, and Electrophysiological Abnormalities of APP-Deficient Mice द्वारा Sabine Ring, Sascha W. Weyer, Susanne B. Kilian, Elaine Waldron, Claus U. Pietrzik, Mikhail A Filippov, Jochen Herms, Christian J. Buchholz, Christopher B. Eckman, Martin Körte, David P Wolfer, Ulrike Müller
प्रकाशित 2007Artigo
खोज साधन:
संबंधित विषय
Biology
Medicine
Disease
Biochemistry
Chemistry
Alzheimer's disease
Internal medicine
Amyloid precursor protein
Cell biology
Gene
Pathology
Amyloid (mycology)
Endocrinology
Neuroscience
Amyloid precursor protein secretase
Enzyme
Genetics
Molecular biology
Peptide
Receptor
Alpha secretase
Amyloid beta
Botany
In vitro
Inorganic chemistry
P3 peptide
Presenilin
Amyloid β
Genetically modified mouse
Insulin-degrading enzyme