Risultati della ricerca - Bridget K. Wagner

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  1. 1
    The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods

    The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods di Bridget K. Wagner, Stuart L. Schreiber

    Pubblicazione 2016
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  2. 2
    Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation

    Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation di Zoltàn Arany, Bridget K. Wagner, Yanhong Ma, Jessica Chinsomboon, Dina Laznik, Bruce M. Spiegelman

    Pubblicazione 2008
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  3. 3
    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs

    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs di Drew Adams, Mingji Dai, Giovanni Pellegrino, Bridget K. Wagner, Andrew M. Stern, Alykhan F. Shamji, Stuart L. Schreiber

    Pubblicazione 2012
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  4. 4
    Engineering designer beta cells with a CRISPR-Cas9 conjugation platform

    Engineering designer beta cells with a CRISPR-Cas9 conjugation platform di Donghyun Lim, Vedagopuram Sreekanth, Kurt J. Cox, Benjamin K. Law, Bridget K. Wagner, Jeffrey M. Karp, Amit Choudhary

    Pubblicazione 2020
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  5. 5
    Assay of the Multiple Energy-Producing Pathways of Mammalian Cells

    Assay of the Multiple Energy-Producing Pathways of Mammalian Cells di Barry R. Bochner, Mark Siri, Richard H. Huang, Shawn Noble, Xiang-He Lei, Paul A. Clemons, Bridget K. Wagner

    Pubblicazione 2011
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  6. 6
    Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme

    Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme di Juan Pablo Maianti, G.A. Tan, Amedeo Vetere, A.J. Welsh, Bridget K. Wagner, Markus A. Seeliger, David R. Liu

    Pubblicazione 2019
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  7. 7
    Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes

    Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes di Ercument Dirice, Raymond W.S. Ng, Rachael N. Martínez, Jiang Hu, Florence F. Wagner, Edward B. Holson, Bridget K. Wagner, Rohit Kulkarni

    Pubblicazione 2017
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  8. 8
    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death

    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death di Drew Adams, Žarko Bošković, Jimmy R. Thériault, Alex J. Wang, Andrew M. Stern, Bridget K. Wagner, Alykhan F. Shamji, Stuart L. Schreiber

    Pubblicazione 2013
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  9. 9
    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma

    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma di Yuan Yuan, Qiu Wang, Joshiawa Paulk, Stefan Kubicek, Melissa M. Kemp, Drew Adams, Alykhan F. Shamji, Bridget K. Wagner, Stuart L. Schreiber

    Pubblicazione 2012
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  10. 10
    Large-scale chemical dissection of mitochondrial function

    Large-scale chemical dissection of mitochondrial function di Bridget K. Wagner, Toshimori Kitami, Tamara J. Gilbert, D. D. Peck, Arvind Ramanathan, Stuart L. Schreiber, Todd R. Golub, Vamsi K. Mootha

    Pubblicazione 2008
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  11. 11
    High-Throughput Luminescent Reporter of Insulin Secretion for Discovering Regulators of Pancreatic Beta-Cell Function

    High-Throughput Luminescent Reporter of Insulin Secretion for Discovering Regulators of Pancreatic Beta-Cell Function di Sean M. Burns, Amedeo Vetere, Deepika Walpita, Vlado Dančík, Carol Khodier, José R. Perez, Paul A. Clemons, Bridget K. Wagner, David Altshuler

    Pubblicazione 2015
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  12. 12
    A one-bead, one-stock solution approach to chemical genetics: part 2

    A one-bead, one-stock solution approach to chemical genetics: part 2 di Paul A. Clemons, Angela N. Koehler, Bridget K. Wagner, Timothy G Sprigings, David R. Spring, Randall W. King, Stuart L. Schreiber, Michael A. Foley

    Pubblicazione 2001
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  13. 13
    Predicting compound activity from phenotypic profiles and chemical structures

    Predicting compound activity from phenotypic profiles and chemical structures di Nikita Moshkov, Tim Becker, Kevin Yang, Péter Horváth, Vlado Dančík, Bridget K. Wagner, Paul A. Clemons, Shantanu Singh, Anne E. Carpenter, Juan C. Caicedo

    Pubblicazione 2023
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  14. 14
    Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis

    Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis di Danny Hung‐Chieh Chou, Edward B. Holson, Florence F. Wagner, Alicia J. Tang, Rebecca L. Maglathlin, Timothy A. Lewis, Stuart L. Schreiber, Bridget K. Wagner

    Pubblicazione 2012
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  15. 15
    Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis–Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial

    Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis–Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial di Dinesh Khanna, Celia J. F. Lin, Daniel E. Furst, Bridget K. Wagner, Mauro Zucchetto, Ganesh Raghu, Fernando J. Martínez, Jonathan Goldin, Jeffrey Siegel, Christopher P. Denton

    Pubblicazione 2021
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  16. 16
    Small-molecule inducers of insulin expression in pancreatic α-cells

    Small-molecule inducers of insulin expression in pancreatic α-cells di Dina Fomina‐Yadlin, Stefan Kubicek, Deepika Walpita, Vlado Dančík, Jacob Hecksher‐Sørensen, Joshua A. Bittker, Tanaz Sharifnia, Alykhan F. Shamji, Paul A. Clemons, Bridget K. Wagner, Stuart L. Schreiber

    Pubblicazione 2010
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  17. 17
    Emerging diabetes therapies: Bringing back the β-cells

    Emerging diabetes therapies: Bringing back the β-cells di Giorgio Basile, Mirza Muhammad Fahd Qadir, Franck Mauvais‐Jarvis, Amedeo Vetere, Veronika M. Shoba, Ashley E. Modell, Ricardo L. Pastori, Holger A. Russ, Bridget K. Wagner, Juan Domínguez‐Bendala

    Pubblicazione 2022
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  18. 18
    A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure

    A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure di Maayan Baron, Adrian Veres, Samuel L. Wolock, Aubrey L. Faust, Renaud Gaujoux, Amedeo Vetere, Jennifer Hyoje Ryu, Bridget K. Wagner, Shai S. Shen-Orr, Allon M. Klein, Douglas A. Melton, Itai Yanai

    Pubblicazione 2016
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  19. 19
    Inhibition of DYRK1A Stimulates Human β-Cell Proliferation

    Inhibition of DYRK1A Stimulates Human β-Cell Proliferation di Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C. Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M. Burns, Tamara J. Gilbert, David E. Olson, Paul A. Clemons, Rohit Kulkarni, Bridget K. Wagner

    Pubblicazione 2016
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  20. 20
    A Human Islet Cell Culture System for High-Throughput Screening

    A Human Islet Cell Culture System for High-Throughput Screening di Deepika Walpita, Thomas P. Hasaka, James Spoonamore, Amedeo Vetere, Karen K. Takane, Dina Fomina‐Yadlin, Nathalie Fiaschi‐Taesch, Alykhan F. Shamji, Paul A. Clemons, Andrew F. Stewart, Stuart L. Schreiber, Bridget K. Wagner

    Pubblicazione 2011
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