Søgeresultater - Bridget K. Wagner

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  1. 1
    The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods

    The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods af Bridget K. Wagner, Stuart L. Schreiber

    Udgivet 2016
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  2. 2
    Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation

    Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation af Zoltàn Arany, Bridget K. Wagner, Yanhong Ma, Jessica Chinsomboon, Dina Laznik, Bruce M. Spiegelman

    Udgivet 2008
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  3. 3
    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs

    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs af Drew Adams, Mingji Dai, Giovanni Pellegrino, Bridget K. Wagner, Andrew M. Stern, Alykhan F. Shamji, Stuart L. Schreiber

    Udgivet 2012
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  4. 4
    Engineering designer beta cells with a CRISPR-Cas9 conjugation platform

    Engineering designer beta cells with a CRISPR-Cas9 conjugation platform af Donghyun Lim, Vedagopuram Sreekanth, Kurt J. Cox, Benjamin K. Law, Bridget K. Wagner, Jeffrey M. Karp, Amit Choudhary

    Udgivet 2020
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  5. 5
    Assay of the Multiple Energy-Producing Pathways of Mammalian Cells

    Assay of the Multiple Energy-Producing Pathways of Mammalian Cells af Barry R. Bochner, Mark Siri, Richard H. Huang, Shawn Noble, Xiang-He Lei, Paul A. Clemons, Bridget K. Wagner

    Udgivet 2011
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  6. 6
    Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme

    Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme af Juan Pablo Maianti, G.A. Tan, Amedeo Vetere, A.J. Welsh, Bridget K. Wagner, Markus A. Seeliger, David R. Liu

    Udgivet 2019
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  7. 7
    Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes

    Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes af Ercument Dirice, Raymond W.S. Ng, Rachael N. Martínez, Jiang Hu, Florence F. Wagner, Edward B. Holson, Bridget K. Wagner, Rohit Kulkarni

    Udgivet 2017
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  8. 8
    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death

    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death af Drew Adams, Žarko Bošković, Jimmy R. Thériault, Alex J. Wang, Andrew M. Stern, Bridget K. Wagner, Alykhan F. Shamji, Stuart L. Schreiber

    Udgivet 2013
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  9. 9
    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma

    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma af Yuan Yuan, Qiu Wang, Joshiawa Paulk, Stefan Kubicek, Melissa M. Kemp, Drew Adams, Alykhan F. Shamji, Bridget K. Wagner, Stuart L. Schreiber

    Udgivet 2012
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  10. 10
    Large-scale chemical dissection of mitochondrial function

    Large-scale chemical dissection of mitochondrial function af Bridget K. Wagner, Toshimori Kitami, Tamara J. Gilbert, D. D. Peck, Arvind Ramanathan, Stuart L. Schreiber, Todd R. Golub, Vamsi K. Mootha

    Udgivet 2008
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  11. 11
    High-Throughput Luminescent Reporter of Insulin Secretion for Discovering Regulators of Pancreatic Beta-Cell Function

    High-Throughput Luminescent Reporter of Insulin Secretion for Discovering Regulators of Pancreatic Beta-Cell Function af Sean M. Burns, Amedeo Vetere, Deepika Walpita, Vlado Dančík, Carol Khodier, José R. Perez, Paul A. Clemons, Bridget K. Wagner, David Altshuler

    Udgivet 2015
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  12. 12
    A one-bead, one-stock solution approach to chemical genetics: part 2

    A one-bead, one-stock solution approach to chemical genetics: part 2 af Paul A. Clemons, Angela N. Koehler, Bridget K. Wagner, Timothy G Sprigings, David R. Spring, Randall W. King, Stuart L. Schreiber, Michael A. Foley

    Udgivet 2001
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  13. 13
    Predicting compound activity from phenotypic profiles and chemical structures

    Predicting compound activity from phenotypic profiles and chemical structures af Nikita Moshkov, Tim Becker, Kevin Yang, Péter Horváth, Vlado Dančík, Bridget K. Wagner, Paul A. Clemons, Shantanu Singh, Anne E. Carpenter, Juan C. Caicedo

    Udgivet 2023
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  14. 14
    Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis

    Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis af Danny Hung‐Chieh Chou, Edward B. Holson, Florence F. Wagner, Alicia J. Tang, Rebecca L. Maglathlin, Timothy A. Lewis, Stuart L. Schreiber, Bridget K. Wagner

    Udgivet 2012
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  15. 15
    Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis–Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial

    Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis–Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial af Dinesh Khanna, Celia J. F. Lin, Daniel E. Furst, Bridget K. Wagner, Mauro Zucchetto, Ganesh Raghu, Fernando J. Martínez, Jonathan Goldin, Jeffrey Siegel, Christopher P. Denton

    Udgivet 2021
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  16. 16
    Small-molecule inducers of insulin expression in pancreatic α-cells

    Small-molecule inducers of insulin expression in pancreatic α-cells af Dina Fomina‐Yadlin, Stefan Kubicek, Deepika Walpita, Vlado Dančík, Jacob Hecksher‐Sørensen, Joshua A. Bittker, Tanaz Sharifnia, Alykhan F. Shamji, Paul A. Clemons, Bridget K. Wagner, Stuart L. Schreiber

    Udgivet 2010
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  17. 17
    Emerging diabetes therapies: Bringing back the β-cells

    Emerging diabetes therapies: Bringing back the β-cells af Giorgio Basile, Mirza Muhammad Fahd Qadir, Franck Mauvais‐Jarvis, Amedeo Vetere, Veronika M. Shoba, Ashley E. Modell, Ricardo L. Pastori, Holger A. Russ, Bridget K. Wagner, Juan Domínguez‐Bendala

    Udgivet 2022
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  18. 18
    A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure

    A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure af Maayan Baron, Adrian Veres, Samuel L. Wolock, Aubrey L. Faust, Renaud Gaujoux, Amedeo Vetere, Jennifer Hyoje Ryu, Bridget K. Wagner, Shai S. Shen-Orr, Allon M. Klein, Douglas A. Melton, Itai Yanai

    Udgivet 2016
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  19. 19
    Inhibition of DYRK1A Stimulates Human β-Cell Proliferation

    Inhibition of DYRK1A Stimulates Human β-Cell Proliferation af Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C. Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M. Burns, Tamara J. Gilbert, David E. Olson, Paul A. Clemons, Rohit Kulkarni, Bridget K. Wagner

    Udgivet 2016
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  20. 20
    A Human Islet Cell Culture System for High-Throughput Screening

    A Human Islet Cell Culture System for High-Throughput Screening af Deepika Walpita, Thomas P. Hasaka, James Spoonamore, Amedeo Vetere, Karen K. Takane, Dina Fomina‐Yadlin, Nathalie Fiaschi‐Taesch, Alykhan F. Shamji, Paul A. Clemons, Andrew F. Stewart, Stuart L. Schreiber, Bridget K. Wagner

    Udgivet 2011
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