Resultats de la cerca - Bridget K. Wagner

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  1. 1
    The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods

    The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods per Bridget K. Wagner, Stuart L. Schreiber

    Publicat 2016
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  2. 2
    Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation

    Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation per Zoltàn Arany, Bridget K. Wagner, Yanhong Ma, Jessica Chinsomboon, Dina Laznik, Bruce M. Spiegelman

    Publicat 2008
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  3. 3
    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs

    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs per Drew Adams, Mingji Dai, Giovanni Pellegrino, Bridget K. Wagner, Andrew M. Stern, Alykhan F. Shamji, Stuart L. Schreiber

    Publicat 2012
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  4. 4
    Engineering designer beta cells with a CRISPR-Cas9 conjugation platform

    Engineering designer beta cells with a CRISPR-Cas9 conjugation platform per Donghyun Lim, Vedagopuram Sreekanth, Kurt J. Cox, Benjamin K. Law, Bridget K. Wagner, Jeffrey M. Karp, Amit Choudhary

    Publicat 2020
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  5. 5
    Assay of the Multiple Energy-Producing Pathways of Mammalian Cells

    Assay of the Multiple Energy-Producing Pathways of Mammalian Cells per Barry R. Bochner, Mark Siri, Richard H. Huang, Shawn Noble, Xiang-He Lei, Paul A. Clemons, Bridget K. Wagner

    Publicat 2011
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  6. 6
    Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme

    Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme per Juan Pablo Maianti, G.A. Tan, Amedeo Vetere, A.J. Welsh, Bridget K. Wagner, Markus A. Seeliger, David R. Liu

    Publicat 2019
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  7. 7
    Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes

    Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes per Ercument Dirice, Raymond W.S. Ng, Rachael N. Martínez, Jiang Hu, Florence F. Wagner, Edward B. Holson, Bridget K. Wagner, Rohit Kulkarni

    Publicat 2017
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  8. 8
    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death

    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death per Drew Adams, Žarko Bošković, Jimmy R. Thériault, Alex J. Wang, Andrew M. Stern, Bridget K. Wagner, Alykhan F. Shamji, Stuart L. Schreiber

    Publicat 2013
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  9. 9
    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma

    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma per Yuan Yuan, Qiu Wang, Joshiawa Paulk, Stefan Kubicek, Melissa M. Kemp, Drew Adams, Alykhan F. Shamji, Bridget K. Wagner, Stuart L. Schreiber

    Publicat 2012
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  10. 10
    Large-scale chemical dissection of mitochondrial function

    Large-scale chemical dissection of mitochondrial function per Bridget K. Wagner, Toshimori Kitami, Tamara J. Gilbert, D. D. Peck, Arvind Ramanathan, Stuart L. Schreiber, Todd R. Golub, Vamsi K. Mootha

    Publicat 2008
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  11. 11
    High-Throughput Luminescent Reporter of Insulin Secretion for Discovering Regulators of Pancreatic Beta-Cell Function

    High-Throughput Luminescent Reporter of Insulin Secretion for Discovering Regulators of Pancreatic Beta-Cell Function per Sean M. Burns, Amedeo Vetere, Deepika Walpita, Vlado Dančík, Carol Khodier, José R. Perez, Paul A. Clemons, Bridget K. Wagner, David Altshuler

    Publicat 2015
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  12. 12
    A one-bead, one-stock solution approach to chemical genetics: part 2

    A one-bead, one-stock solution approach to chemical genetics: part 2 per Paul A. Clemons, Angela N. Koehler, Bridget K. Wagner, Timothy G Sprigings, David R. Spring, Randall W. King, Stuart L. Schreiber, Michael A. Foley

    Publicat 2001
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  13. 13
    Predicting compound activity from phenotypic profiles and chemical structures

    Predicting compound activity from phenotypic profiles and chemical structures per Nikita Moshkov, Tim Becker, Kevin Yang, Péter Horváth, Vlado Dančík, Bridget K. Wagner, Paul A. Clemons, Shantanu Singh, Anne E. Carpenter, Juan C. Caicedo

    Publicat 2023
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  14. 14
    Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis

    Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis per Danny Hung‐Chieh Chou, Edward B. Holson, Florence F. Wagner, Alicia J. Tang, Rebecca L. Maglathlin, Timothy A. Lewis, Stuart L. Schreiber, Bridget K. Wagner

    Publicat 2012
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  15. 15
    Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis–Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial

    Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis–Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial per Dinesh Khanna, Celia J. F. Lin, Daniel E. Furst, Bridget K. Wagner, Mauro Zucchetto, Ganesh Raghu, Fernando J. Martínez, Jonathan Goldin, Jeffrey Siegel, Christopher P. Denton

    Publicat 2021
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  16. 16
    Small-molecule inducers of insulin expression in pancreatic α-cells

    Small-molecule inducers of insulin expression in pancreatic α-cells per Dina Fomina‐Yadlin, Stefan Kubicek, Deepika Walpita, Vlado Dančík, Jacob Hecksher‐Sørensen, Joshua A. Bittker, Tanaz Sharifnia, Alykhan F. Shamji, Paul A. Clemons, Bridget K. Wagner, Stuart L. Schreiber

    Publicat 2010
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  17. 17
    Emerging diabetes therapies: Bringing back the β-cells

    Emerging diabetes therapies: Bringing back the β-cells per Giorgio Basile, Mirza Muhammad Fahd Qadir, Franck Mauvais‐Jarvis, Amedeo Vetere, Veronika M. Shoba, Ashley E. Modell, Ricardo L. Pastori, Holger A. Russ, Bridget K. Wagner, Juan Domínguez‐Bendala

    Publicat 2022
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  18. 18
    A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure

    A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure per Maayan Baron, Adrian Veres, Samuel L. Wolock, Aubrey L. Faust, Renaud Gaujoux, Amedeo Vetere, Jennifer Hyoje Ryu, Bridget K. Wagner, Shai S. Shen-Orr, Allon M. Klein, Douglas A. Melton, Itai Yanai

    Publicat 2016
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  19. 19
    Inhibition of DYRK1A Stimulates Human β-Cell Proliferation

    Inhibition of DYRK1A Stimulates Human β-Cell Proliferation per Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C. Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M. Burns, Tamara J. Gilbert, David E. Olson, Paul A. Clemons, Rohit Kulkarni, Bridget K. Wagner

    Publicat 2016
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  20. 20
    A Human Islet Cell Culture System for High-Throughput Screening

    A Human Islet Cell Culture System for High-Throughput Screening per Deepika Walpita, Thomas P. Hasaka, James Spoonamore, Amedeo Vetere, Karen K. Takane, Dina Fomina‐Yadlin, Nathalie Fiaschi‐Taesch, Alykhan F. Shamji, Paul A. Clemons, Andrew F. Stewart, Stuart L. Schreiber, Bridget K. Wagner

    Publicat 2011
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