Результаты поиска - Alykhan F. Shamji

Отмена результатов
  1. 1
    Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins

    Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins по Alykhan F. Shamji, Finny G. Kuruvilla, Stuart L. Schreiber

    Опубликовано 2000
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  2. 2
    Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

    Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins по James S. Hardwick, Finny G. Kuruvilla, Jeffrey K. Tong, Alykhan F. Shamji, Stuart L. Schreiber

    Опубликовано 1999
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  3. 3
    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs

    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs по Drew Adams, Mingji Dai, Giovanni Pellegrino, Bridget K. Wagner, Andrew M. Stern, Alykhan F. Shamji, Stuart L. Schreiber

    Опубликовано 2012
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  4. 4
    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death

    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death по Drew Adams, Žarko Bošković, Jimmy R. Thériault, Alex J. Wang, Andrew M. Stern, Bridget K. Wagner, Alykhan F. Shamji, Stuart L. Schreiber

    Опубликовано 2013
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  5. 5
    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma

    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma по Yuan Yuan, Qiu Wang, Joshiawa Paulk, Stefan Kubicek, Melissa M. Kemp, Drew Adams, Alykhan F. Shamji, Bridget K. Wagner, Stuart L. Schreiber

    Опубликовано 2012
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  6. 6
    <i>KRAS</i> Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine

    <i>KRAS</i> Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine по Michelle L. Stewart, Pablo Tamayo, Andrew J. Wilson, Stephanie Wang, Daniel Y. Chang, Jong W. Kim, Dineo Khabele, Alykhan F. Shamji, Stuart L. Schreiber

    Опубликовано 2015
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  7. 7
    Small-molecule inducers of insulin expression in pancreatic α-cells

    Small-molecule inducers of insulin expression in pancreatic α-cells по Dina Fomina‐Yadlin, Stefan Kubicek, Deepika Walpita, Vlado Dančík, Jacob Hecksher‐Sørensen, Joshua A. Bittker, Tanaz Sharifnia, Alykhan F. Shamji, Paul A. Clemons, Bridget K. Wagner, Stuart L. Schreiber

    Опубликовано 2010
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  8. 8
    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes

    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes по Drew Adams, Daisuke Ito, Matthew G. Rees, Brinton Seashore‐Ludlow, Xiaoling Puyang, Alex H. Ramos, Jaime H. Cheah, Paul A. Clemons, Markus Warmuth, Ping Zhu, Alykhan F. Shamji, Stuart L. Schreiber

    Опубликовано 2014
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  9. 9
    A Human Islet Cell Culture System for High-Throughput Screening

    A Human Islet Cell Culture System for High-Throughput Screening по Deepika Walpita, Thomas P. Hasaka, James Spoonamore, Amedeo Vetere, Karen K. Takane, Dina Fomina‐Yadlin, Nathalie Fiaschi‐Taesch, Alykhan F. Shamji, Paul A. Clemons, Andrew F. Stewart, Stuart L. Schreiber, Bridget K. Wagner

    Опубликовано 2011
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  10. 10
    Selective killing of cancer cells by a small molecule targeting the stress response to ROS

    Selective killing of cancer cells by a small molecule targeting the stress response to ROS по Lakshmi Raj, Takao Ide, Aditi U. Gurkar, Michael Foley, Monica Schenone, Xiaoyu Li, Nicola Tolliday, Todd R. Golub, Steven A. Carr, Alykhan F. Shamji, Andrew M. Stern, Anna Mandinova, Stuart L. Schreiber, Sam W. Lee

    Опубликовано 2011
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  11. 11
    Multiplex Cytological Profiling Assay to Measure Diverse Cellular States

    Multiplex Cytological Profiling Assay to Measure Diverse Cellular States по Sigrun Gustafsdottir, Vebjorn Ljosa, Katherine L Sokolnicki, Joshua Wilson, Deepika Walpita, Melissa M. Kemp, Kathleen Petri Seiler, Hyman A. Carrel, Todd R. Golub, Stuart L. Schreiber, Paul A. Clemons, Anne E. Carpenter, Alykhan F. Shamji

    Опубликовано 2013
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  12. 12
    Regulation of Ferroptotic Cancer Cell Death by GPX4

    Regulation of Ferroptotic Cancer Cell Death by GPX4 по Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch, Kaoru Shimada, Rachid Skouta, Vasanthi S. Viswanathan, Jaime H. Cheah, Paul A. Clemons, Alykhan F. Shamji, Clary B. Clish, Lewis M. Brown, Albert W. Girotti, Virginia W. Cornish, Stuart L. Schreiber, Brent R. Stockwell

    Опубликовано 2014
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  13. 13
    Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules

    Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules по Stanley Y. Shaw, Khoa Tran, Adam Castoreno, Joanna M. Peloquin, Kara G. Lassen, Bernard Khor, Leslie N. Aldrich, Pauline H. Tan, Daniel B. Graham, Petric Kuballa, Gautam Goel, Mark J. Daly, Alykhan F. Shamji, Stuart L. Schreiber, Ramnik J. Xavier

    Опубликовано 2013
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  14. 14
    Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

    Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics по Szu-Yu Kuo, Adam Castoreno, Leslie N. Aldrich, Kara G. Lassen, Gautam Goel, Vlado Dančík, Petric Kuballa, Isabel Latorre, Kara L. Conway, Sovan Sarkar, Dorothea Maetzel, Rudolf Jaenisch, Paul A. Clemons, Stuart L. Schreiber, Alykhan F. Shamji, Ramnik J. Xavier

    Опубликовано 2015
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  15. 15
    Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease

    Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease по Elizaveta S. Leshchiner, Jason S. Rush, Michael A. Durney, Zhifang Cao, Vlado Dančík, Benjamin Chittick, Huixian Wu, Adam Petrone, Joshua A. Bittker, Andrew J. Phillips, José R. Perez, Alykhan F. Shamji, Virendar K. Kaushik, Mark J. Daly, Daniel B. Graham, Stuart L. Schreiber, Ramnik J. Xavier

    Опубликовано 2017
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  16. 16
    Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells

    Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells по Thomas B. Sundberg, Hwan Geun Choi, Joo‐Hye Song, Caitlin Russell, Mahmud M. Hussain, Daniel B. Graham, Bernard Khor, John D Gagnon, Daniel J. O’Connell, Kavitha Narayan, Vlado Dančík, José R. Perez, Hans‐Christian Reinecker, Nathanael S. Gray, Stuart L. Schreiber, Ramnik J. Xavier, Alykhan F. Shamji

    Опубликовано 2014
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  17. 17
    Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation

    Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation по Zhifang Cao, Kara L. Conway, Robert J. W. Heath, Jason S. Rush, Elizaveta S. Leshchiner, Zaida G. Ramirez‐Ortiz, Natalia B. Nedelsky, Hailiang Huang, Aylwin Ng, Agnès Gardet, Shih‐Chin Cheng, Alykhan F. Shamji, John D. Rioux, Cisca Wijmenga, Mihai G. Netea, Terry K. Means, Mark J. Daly, Ramnik J. Xavier

    Опубликовано 2015
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  18. 18
    A genetic basis for the variation in the vulnerability of cancer to DNA damage

    A genetic basis for the variation in the vulnerability of cancer to DNA damage по Brian D. Yard, Drew Adams, Eui Kyu Chie, Pablo Tamayo, Jessica Battaglia, Priyanka Gopal, Kevin Rogacki, Bradley Pearson, James G. Phillips, Daniel P. Raymond, Nathan A. Pennell, Francisco A. Almeida, Jaime H. Cheah, Paul A. Clemons, Alykhan F. Shamji, Craig D. Peacock, Stuart L. Schreiber, Peter S. Hammerman, Mohamed E. Abazeed

    Опубликовано 2016
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  19. 19
    Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells

    Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells по Liv Johannessen, Thomas B. Sundberg, Daniel J. O’Connell, Raivo Kolde, James Berstler, Katelyn Billings, Bernard Khor, Brinton Seashore‐Ludlow, Anne Fassl, Caitlin Russell, Isabel Latorre, Baishan Jiang, Daniel B. Graham, José R. Perez, Piotr Siciński, Andrew J. Phillips, Stuart L. Schreiber, Nathanael S. Gray, Alykhan F. Shamji, Ramnik J. Xavier

    Опубликовано 2017
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  20. 20
    A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay

    A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay по Mark‐Anthony Bray, Sigrun Gustafsdottir, Mohammad Hossein Rohban, Shantanu Singh, Vebjorn Ljosa, Katherine L Sokolnicki, Joshua A. Bittker, Nicole E. Bodycombe, Vlado Dančík, Thomas P. Hasaka, Cindy Hon, Melissa M. Kemp, Kejie Li, Deepika Walpita, Mathias J. Wawer, Todd R. Golub, Stuart L. Schreiber, Paul A. Clemons, Alykhan F. Shamji, Anne E. Carpenter

    Опубликовано 2017
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