Resultados da pesquisa

Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1 Por Michael B. Lazarus, Kevan M. Shokat

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NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor Por Abel Martín-Garrido, David Brown, Alicia N. Lyle, Anna Dikalova, Bonnie Seidel-Rogol, Bernard Lassègue, Alejandra San Martín, Kathy K. Griendling

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Cyclic GMP-dependent protein phosphorylation in intact medial tissue and isolated cells from vascular smooth muscle. Por J E Casnellie, Harlan E. Ives, James D. Jamieson, Paul Greengard

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Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate Por Z Liu, Yifei Lv, Na Zhao, G Guan, J Wang

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The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in K... Por Gwyn W. Gould, Ana Cuenda, Fiona Thomson, Patricia T.W. Cohen

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Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells. Por Olivier Donzé, Rosemary Jagus, Antonis E. Koromilas, John W.B. Hershey, Nahum Sonenberg

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CEP‐1347 (KT7515), an Inhibitor of JNK Activation, Rescues Sympathetic Neurons and Neuronally Differentiated PC12 Cells from Death Evoked by three Distinct Insults Por Anna C. Maroney, James P. Finn, Donna Bozyczko‐Coyne, Teresa M. O’Kane, Nicola T. Neff, Aviva M. Tolkovsky, David S. Park, Chao Yan, Carol M. Troy, Lloyd A. Greene

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Kinetic parameters of the protein tyrosine kinase activity of EGF-receptor mutants with individually altered autophosphorylation sites. Por Annemarie Honegger, Thomas J. Dull, Daniele Szapary, Akira Komoriya, Richard Kris, A Ullrich, Joseph Schlessinger

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Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries. Por Hang Jiang, Janet L. Colbran, Sharron H. Francis, Jackie D. Corbin

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The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acu... Por Robert M. Tombes, L. Kelly AUER, Ross B. Mikkelsen, Kristoffer Valerie, Matthias P. Wymann, Jeannette Marshall, Martin McMahon, Paul Dent

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Synthetic approaches to protein phosphorylation Por Zan Chen, Philip A. Cole

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Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor pervanadate (vanadyl hydroperoxide) Por Kevin Pumiglia, Lester F. Lau, Chang Huang, Susan F Burroughs, Maurice B. Feinstein

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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A Por Pui‐Mun Wong, Yan Feng, Junru Wang, Rong Shi, Xuejun Jiang

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Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus Por Mark J. W. Hanssen, Joris Hoeks, Boudewijn Brans, Anouk A.J.J. van der Lans, Gert Schaart, José J. van den Driessche, Johanna A. Jörgensen, Mark V. Boekschoten, Matthijs K. C. Hesselink, Bas Havekes, Sander Kersten, Felix M. Mottaghy, Wouter D. van Marken Lichtenbelt, Patrick Schrauwen

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Kinase activator protein mediates longer-term effects of starvation on activity of pyruvate dehydrogenase kinase in rat liver mitochondria Por Gareth Denyer, A L Kerbey, P J Randle

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Triggering of Suicidal Erythrocyte Death Following Boswellic Acid Exposure Por Salvatrice Calabrò, Kousi Alzoubi, Caterina Faggio, Stefan Laufer, Florian Läng

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Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage Por Loretta Oghenekome Iniaghe, Paul R. Krafft, Damon Klebe, Eric K. I. Omogbai, John H. Zhang, Jiping Tang

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Mechanism of Interferon Action Por Laura G. Ortega, MATTHEW D. MCCOTTER, GILBERT L. HENRY, Stephen J. McCormack, Daniel C. Thomis, Charles E. Samuel

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Inhibition of Protein Kinase C by Staurosporine Promotes Elevated Accumulations of Inositol Trisphosphates and Tetrakisphosphate in Human Platelets Exposed to Thrombin Por W G King, S E Rittenhouse

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Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice Por Joseph R. Burgoyne, Olena Rudyk, Hyun-Ju Cho, Oleksandra Prysyazhna, Natasha Hathaway, Amanda Weeks, Rachel Evans, Tony Ng, Katrin Schröder, Ralf P. Brandes, Ajay M. Shah, Philip Eaton

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