Resultats de la cerca - Martin McMahon

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  1. 1
    Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy.

    Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy. per J. Thorburn, Martin McMahon, Andrew Thorburn

    Publicat 1994
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  2. 2
    Oncogenic Raf-1 Activates p70 S6 Kinase via a Mitogen-activated Protein Kinase-independent Pathway

    Oncogenic Raf-1 Activates p70 S6 Kinase via a Mitogen-activated Protein Kinase-independent Pathway per Philippe Lenormand, Martin McMahon, Jacques Pouysségur

    Publicat 1996
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  3. 3
    The Repertoire of Fos and Jun Proteins Expressed during the G<sub>1</sub> Phase of the Cell Cycle Is Determined by the Duration of Mitogen-Activated Protein Kinase Activation

    The Repertoire of Fos and Jun Proteins Expressed during the G<sub>1</sub> Phase of the Cell Cycle Is Determined by the Duration of Mitogen-Activated Protein Kinase Activation per Simon J. Cook, Natasha Aziz, Martin McMahon

    Publicat 1999
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  4. 4
    Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events.

    Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events. per J. Hambleton, Martin McMahon, Anthony DeFranco

    Publicat 1995
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  5. 5
    BRAFV600E Cooperates with PI3K Signaling, Independent of AKT, to Regulate Melanoma Cell Proliferation

    BRAFV600E Cooperates with PI3K Signaling, Independent of AKT, to Regulate Melanoma Cell Proliferation per Jillian M. Silva, Christina A. Bulman, Martin McMahon

    Publicat 2014
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  6. 6
    Interferon-induced gene expression in wild-type and interferon-resistant human lymphoblastoid (Daudi) cells

    Interferon-induced gene expression in wild-type and interferon-resistant human lymphoblastoid (Daudi) cells per Martin McMahon, George R. Stark, Ian M. Kerr

    Publicat 1986
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  7. 7
    Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells

    Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells per Ashish Banerjee, Raffi Gugasyan, Martin McMahon, Steve Gerondakis

    Publicat 2006
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  8. 8
    Senescence of human fibroblasts induced by oncogenic Raf

    Senescence of human fibroblasts induced by oncogenic Raf per Jiyue Zhu, Douglas Woods, Martin McMahon, J. Michael Bishop

    Publicat 1998
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  9. 9
    Pharmacologic Inhibition of RAF→MEK→ERK Signaling Elicits Pancreatic Cancer Cell Cycle Arrest Through Induced Expression of p27Kip1

    Pharmacologic Inhibition of RAF→MEK→ERK Signaling Elicits Pancreatic Cancer Cell Cycle Arrest Through Induced Expression of p27Kip1 per Stephan Gysin, Sanghyun Lee, Nicholas M. Dean, Martin McMahon

    Publicat 2005
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  10. 10
    Conditionally Oncogenic Forms of the A-Raf and B-Raf Protein Kinases Display Different Biological and Biochemical Properties in NIH 3T3 Cells

    Conditionally Oncogenic Forms of the A-Raf and B-Raf Protein Kinases Display Different Biological and Biochemical Properties in NIH 3T3 Cells per Catrin Pritchard, Michael L. Samuels, Elizabeth Bosch, Martin McMahon

    Publicat 1995
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  11. 11
    Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.

    Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase. per Michael L. Samuels, Michèle Weber, J. Michael Bishop, Martin McMahon

    Publicat 1993
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  12. 12
    Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond

    Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond per Matthew Holderfield, Marian M. Deuker, Frank McCormick, Martin McMahon

    Publicat 2014
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  13. 13
    Diminished WNT → β-catenin → c-MYC signaling is a barrier for malignant progression of BRAF<sup>V600E</sup>-induced lung tumors

    Diminished WNT → β-catenin → c-MYC signaling is a barrier for malignant progression of BRAF<sup>V600E</sup>-induced lung tumors per Joseph Juan, Teruyuki Muraguchi, Gioia Iezza, Rosalie C. Sears, Martin McMahon

    Publicat 2014
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  14. 14
    Mutationally Activated BRAFV600E Elicits Papillary Thyroid Cancer in the Adult Mouse

    Mutationally Activated BRAFV600E Elicits Papillary Thyroid Cancer in the Adult Mouse per Roch‐Philippe Charles, Gioia Iezza, Elena Amendola, David Dankort, Martin McMahon

    Publicat 2011
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  15. 15
    PI3′-Kinase Inhibition Forestalls the Onset of MEK1/2 Inhibitor Resistance in <i>BRAF</i>-Mutated Melanoma

    PI3′-Kinase Inhibition Forestalls the Onset of MEK1/2 Inhibitor Resistance in <i>BRAF</i>-Mutated Melanoma per Marian M. Deuker, Victoria Marsh Durban, Wayne A. Phillips, Martin McMahon

    Publicat 2014
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  16. 16
    Ras-Raf-Arf Signaling Critically Depends on the Dmp1 Transcription Factor

    Ras-Raf-Arf Signaling Critically Depends on the Dmp1 Transcription Factor per Ramesh Sreeramaneni, Asif Chaudhry, Martin McMahon, Charles J. Sherr, Kazushi Inoue

    Publicat 2004
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  17. 17
    Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene

    Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene per Catrin Pritchard, Laurel M. Bolin, Robyn M. Slattery, Robert Murray, Martin McMahon

    Publicat 1996
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  18. 18
    Activating BRAF and PIK3CA Mutations Cooperate to Promote Anaplastic Thyroid Carcinogenesis

    Activating BRAF and PIK3CA Mutations Cooperate to Promote Anaplastic Thyroid Carcinogenesis per Roch‐Philippe Charles, Jillian Silva, Gioia Iezza, Wayne A. Phillips, Martin McMahon

    Publicat 2014
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  19. 19
    Analysis of the transcriptional program induced by Raf in epithelial cells

    Analysis of the transcriptional program induced by Raf in epithelial cells per Almut Schulze, Kerstin Lehmann, Harold B.J. Jefferies, Martin McMahon, Julian Downward

    Publicat 2001
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  20. 20
    Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21<sup>Cip1</sup>

    Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21<sup>Cip1</sup> per Douglas Woods, David Parry, Holly Cherwinski, Elizabeth Bosch, Emma Lees, Martin McMahon

    Publicat 1997
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