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  1. 1
    BRD4 Structure–Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536

    BRD4 Structure–Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536 by Lijia Chen, Jeremy L. Yap, Makoto Yoshioka, Maryanna E. Lanning, Rachel N. Fountain, Mithun Raje, Jacob A. Scheenstra, Jeffrey Strovel, Steven Fletcher

    Published 2015
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  2. 2
    Methylation of histone H3 lysine 9 occurs during translation

    Methylation of histone H3 lysine 9 occurs during translation by Carlos Rondón, Francisco Saavedra, Francisca Alvarez, César Díaz-Celis, Valentina Ugalde, Jianhua Li, Ignasi Forné, Zachary A. Gurard‐Levin, Geneviève Almouzni, Axel Imhof, Alejandra Loyola

    Published 2015
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  3. 3
    BET bromodomain protein inhibition is a therapeutic option for medulloblastoma

    BET bromodomain protein inhibition is a therapeutic option for medulloblastoma by Anton G. Henssen, Theresa Thor, Andrea Odersky, Lukas C. Heukamp, Nicolai El-Hindy, Anneleen Beckers, Frank Speleman, Kristina Althoff, Simon Schäfers, Alexander Schramm, Ulrich Sure, Gudrun Fleischhack, Angelika Eggert, Johannes H. Schulte

    Published 2013
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  4. 4
    Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

    Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 by Jing Lü, Yimin Qian, Martha Altieri, Hanqing Dong, Jing Wang, Kanak Raina, John Hines, James D. Winkler, Andrew P. Crew, Kevin Coleman, Craig M. Crews

    Published 2015
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  5. 5
    Nonrandom utilization of acetylation sites in histones isolated from Tetrahymena. Evidence for functionally distinct H4 acetylation sites.

    Nonrandom utilization of acetylation sites in histones isolated from Tetrahymena. Evidence for functionally distinct H4 acetylation sites. by L Chicoine, Ira G. Schulman, R Richman, Richard G. Cook, C. David Allis

    Published 1986
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  6. 6
    Two faces of BRD4

    Two faces of BRD4 by Ballachanda N. Devaiah, Dinah S. Singer

    Published 2013
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  7. 7
    BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia

    BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia by Jae‐Seok Roe, Fatih Mercan, Keith Rivera, Darryl Pappin, Christopher R. Vakoc

    Published 2015
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  8. 8
    The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models

    The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models by Patrick L. Garcia, Aubrey L. Miller, Kelly M. Kreitzburg, Leona N. Council, Tracy L. Gamblin, John D. Christein, Marty J. Heslin, J. Pablo Arnoletti, Joseph H. Richardson, D Chen, C. Alexandra Hanna, S L Cramer, Eddy S. Yang, Jun Qi, James E. Bradner, Karina J. Yoon

    Published 2015
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  9. 9
    Phthalimide conjugation as a strategy for in vivo target protein degradation

    Phthalimide conjugation as a strategy for in vivo target protein degradation by Georg E. Winter, Dennis L. Buckley, Joshiawa Paulk, Justin M. Roberts, Amanda Souza, Sirano Dhe‐Paganon, James E. Bradner

    Published 2015
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  10. 10
    Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors

    Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors by Gopalakrishnan Ramakrishnan, Hittu Matta, Bhairavi Tolani, Timothy J. Triche, Preet M. Chaudhary

    Published 2015
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  11. 11
    The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation

    The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation by Chiara Pastori, Philipp Kapranov, Clara Penas, Veronica J. Peschansky, Claude‐Henry Volmar, Jann N. Sarkaria, Amadé Bregy, Ricardo J. Komotar, Georges St. Laurent, Nagi G. Ayad, Claes Wahlestedt

    Published 2015
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  12. 12
    BET bromodomain inhibition suppresses transcriptional responses to cytokine‐Jak‐STAT signaling in a gene‐specific manner in human monocytes

    BET bromodomain inhibition suppresses transcriptional responses to cytokine‐Jak‐STAT signaling in a gene‐specific manner in human monocytes by Chun Hin Chan, Celestia Fang, Yu Qiao, Anna Yarilina, Rab K. Prinjha, Lionel B. Ivashkiv

    Published 2014
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  13. 13
    Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration

    Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration by Sungjin Ko, Tae‐Young Choi, Jacquelyn O. Russell, Juhoon So, Satdarshan P. Monga, Donghun Shin

    Published 2015
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  14. 14
    BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries

    BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries by Bowen Wang, Mengxue Zhang, Toshio Takayama, Xudong Shi, Drew Alan Roenneburg, K. Craig Kent, Lian‐Wang Guo

    Published 2015
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  15. 15
    Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism

    Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism by Huasong Lu, Yuhua Xue, Guoying Karen Yu, Carolina Arias, Julie Lin, Susan Fong, Michel Faure, Ben Weisburd, Xiao‐Dan Ji, Alexandre Mercier, James Sutton, Kunxin Luo, Zhenhai Gao, Qiang Zhou

    Published 2015
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  16. 16
    Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery

    Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery by Leilei Fu, Mao Tian, Xiang Li, Jing Li, Jian Huang, Liang Ouyang, Yonghui Zhang, Bo Liu

    Published 2015
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  17. 17
    Targeted Recruitment of the Sin3-Rpd3 Histone Deacetylase Complex Generates a Highly Localized Domain of Repressed Chromatin In Vivo

    Targeted Recruitment of the Sin3-Rpd3 Histone Deacetylase Complex Generates a Highly Localized Domain of Repressed Chromatin In Vivo by David Kadosh, Kevin Struhl

    Published 1998
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  18. 18
    An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression

    An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reacti... by Gilles Darcis, Anna Kula, Sophie Bouchat, Koh Fujinaga, Francis Corazza, Amina Aït-Ammar, Nadège Delacourt, Adeline Mélard, Kabamba Kabeya, Caroline Vanhulle, Benoît Van Driessche, Jean-Stéphane Gatot, Thomas Cherrier, Luiz F. Pianowski, Lúcio Gama, Christian Schwartz, Jorge Vila, Arsène Burny, Nathan Clumeck, Michel Moutschen, Stéphane De Wit, B. Matija Peterlin, Christine Rouzioux, Olivier Rohr, Carine Van Lint

    Published 2015
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  19. 19
    Genetic Analysis of brahma: The Drosophila Homolog of the Yeast Chromatin Remodeling Factor SWI2/SNF2

    Genetic Analysis of brahma: The Drosophila Homolog of the Yeast Chromatin Remodeling Factor SWI2/SNF2 by Lisa Elfring, Carla Daniel, Ophelia Papoulas, Renate Deuring, Melinda Sarte, Sarah Moseley, Shelley J Beek, W. Ross Waldrip, Gary Daubresse, Angela H. DePace, James A. Kennison, John W. Tamkun

    Published 1998
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  20. 20
    Bromodomain-dependent stage-specific male genome programming by Brdt

    Bromodomain-dependent stage-specific male genome programming by Brdt by Jonathan Gaucher, Fayçal Boussouar, Emilie Montellier, Sandrine Curtet, Thierry Buchou, Sarah Bertrand, Patrick Héry, Sylvie Jounier, Arnaud Depaux, Anne-Laure Vitte, Philippe Guardiola, Karin Pernet, Alexandra Debernardi, Fabrice Lopez, Hélène Holota, Jean Imbert, Debra J. Wolgemuth, Matthieu Gérard, Sophie Rousseaux, Saadi Khochbin

    Published 2012
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