Resultats de la cerca - James E. Bradner

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  1. 1
    The use of small molecules in somatic-cell reprogramming

    The use of small molecules in somatic-cell reprogramming per Alexander Federation, James E. Bradner, Alexander Meissner

    Publicat 2013
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  2. 2
    Therapeutic Strategies to Inhibit MYC

    Therapeutic Strategies to Inhibit MYC per Michael R. McKeown, James E. Bradner

    Publicat 2014
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  3. 3
    Transcriptional Addiction in Cancer

    Transcriptional Addiction in Cancer per James E. Bradner, Denes Hnisz, Richard A. Young

    Publicat 2017
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  4. 4
    Chromatin modifications as therapeutic targets in MLL-rearranged leukemia

    Chromatin modifications as therapeutic targets in MLL-rearranged leukemia per Aniruddha J. Deshpande, James E. Bradner, Scott A. Armstrong

    Publicat 2012
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  5. 5
    Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins

    Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins per William W. Lockwood, Kreshnik Zejnullahu, James E. Bradner, Harold Varmus

    Publicat 2012
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  6. 6
    Erratum: A chemical probe toolbox for dissecting the cancer epigenome

    Erratum: A chemical probe toolbox for dissecting the cancer epigenome per Jake Shortt, Christopher J. Ott, Ricky W. Johnstone, James E. Bradner

    Publicat 2017
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  7. 7
    Discovery of histone deacetylase 8 selective inhibitors

    Discovery of histone deacetylase 8 selective inhibitors per Weiping Tang, Tuoping Luo, Edward F. Greenberg, James E. Bradner, Stuart L. Schreiber

    Publicat 2011
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  8. 8
    Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA

    Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA per Xin Wang, Christine M. Helfer, Neha J. Pancholi, James E. Bradner, Jianxin You

    Publicat 2013
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  9. 9
    On the inhibition of histone deacetylase 8

    On the inhibition of histone deacetylase 8 per Guillermina Estiú, Nathan West, Ralph Mazitschek, Edward F. Greenberg, James E. Bradner, Olaf Wiest

    Publicat 2010
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  10. 10
    Targeting the MYC and PI3K Pathways Eliminates Leukemia-Initiating Cells in T-cell Acute Lymphoblastic Leukemia

    Targeting the MYC and PI3K Pathways Eliminates Leukemia-Initiating Cells in T-cell Acute Lymphoblastic Leukemia per Suzanne Schubbert, Anjelica Cardenas, Harrison Chen, Consuelo Garcia, Wei Guo, James E. Bradner, Hong Wu

    Publicat 2014
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  11. 11
    Total Synthesis and Biological Mode of Action of Largazole: A Potent Class I Histone Deacetylase Inhibitor

    Total Synthesis and Biological Mode of Action of Largazole: A Potent Class I Histone Deacetylase Inhibitor per Albert A. Bowers, Nathan West, Jack Taunton, Stuart L. Schreiber, James E. Bradner, Robert M. Williams

    Publicat 2008
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  12. 12
    Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD

    Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD per Xia Zhou, Lucy X. Fan, Dorien J.M. Peters, Marie Trudel, James E. Bradner, Xiaogang Li

    Publicat 2015
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  13. 13
    BET and BRAF inhibitors act synergistically against <i>BRAF‐</i>mutant melanoma

    BET and BRAF inhibitors act synergistically against <i>BRAF‐</i>mutant melanoma per Luca Paoluzzi, Douglas Hanniford, Elena Sokolova, Iman Osman, Farbod Darvishian, Jinhua Wang, James E. Bradner, Eva Hernando

    Publicat 2016
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  14. 14
    Relative Binding Free Energy Calculations Applied to Protein Homology Models

    Relative Binding Free Energy Calculations Applied to Protein Homology Models per Daniel Cappel, Michelle Lynn Hall, Eelke B. Lenselink, Thijs Beuming, Jun Qi, James E. Bradner, Woody Sherman

    Publicat 2016
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  15. 15
    SD-1029 Inhibits Signal Transducer and Activator of Transcription 3 Nuclear Translocation

    SD-1029 Inhibits Signal Transducer and Activator of Transcription 3 Nuclear Translocation per Zhenfeng Duan, James E. Bradner, Edward F. Greenberg, Ross L. Levine, Rosemary Foster, Jennifer Mahoney, Michael V. Seiden

    Publicat 2006
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  16. 16
    Chemical phylogenetics of histone deacetylases

    Chemical phylogenetics of histone deacetylases per James E. Bradner, Nathan West, Melissa L. Grachan, Edward F. Greenberg, Stephen J. Haggarty, Tandy Warnow, Ralph Mazitschek

    Publicat 2010
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  17. 17
    The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects

    The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects per Jeyran Shahbazi, Pei Y. Liu, Bernard Atmadibrata, James E. Bradner, Glenn M. Marshall, Richard B. Lock, Tao Liu

    Publicat 2016
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  18. 18
    Phthalimide conjugation as a strategy for in vivo target protein degradation

    Phthalimide conjugation as a strategy for in vivo target protein degradation per Georg E. Winter, Dennis L. Buckley, Joshiawa Paulk, Justin M. Roberts, Amanda Souza, Sirano Dhe‐Paganon, James E. Bradner

    Publicat 2015
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  19. 19
    Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA

    Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA per Zhenhua Zou, Bin Huang, Xinxing Wu, H Zhang, Jun Qi, James E. Bradner, S.K. Nair, L-F Chen

    Publicat 2013
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  20. 20
    Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions

    Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions per Ji Xiong, Daniel Benjamin Dadon, Brian J. Abraham, Tong Ihn Lee, Rudolf Jaenisch, James E. Bradner, Richard A. Young

    Publicat 2015
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