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BRD4 Structure–Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536 Autor Lijia Chen, Jeremy L. Yap, Makoto Yoshioka, Maryanna E. Lanning, Rachel N. Fountain, Mithun Raje, Jacob A. Scheenstra, Jeffrey Strovel, Steven Fletcher

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Methylation of histone H3 lysine 9 occurs during translation Autor Carlos Rondón, Francisco Saavedra, Francisca Alvarez, César Díaz-Celis, Valentina Ugalde, Jianhua Li, Ignasi Forné, Zachary A. Gurard‐Levin, Geneviève Almouzni, Axel Imhof, Alejandra Loyola

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BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Autor Anton G. Henssen, Theresa Thor, Andrea Odersky, Lukas C. Heukamp, Nicolai El-Hindy, Anneleen Beckers, Frank Speleman, Kristina Althoff, Simon Schäfers, Alexander Schramm, Ulrich Sure, Gudrun Fleischhack, Angelika Eggert, Johannes H. Schulte

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Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 Autor Jing Lü, Yimin Qian, Martha Altieri, Hanqing Dong, Jing Wang, Kanak Raina, John Hines, James D. Winkler, Andrew P. Crew, Kevin Coleman, Craig M. Crews

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Nonrandom utilization of acetylation sites in histones isolated from Tetrahymena. Evidence for functionally distinct H4 acetylation sites. Autor L Chicoine, Ira G. Schulman, R Richman, Richard G. Cook, C. David Allis

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Two faces of BRD4 Autor Ballachanda N. Devaiah, Dinah S. Singer

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BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia Autor Jae‐Seok Roe, Fatih Mercan, Keith Rivera, Darryl Pappin, Christopher R. Vakoc

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The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models Autor Patrick L. Garcia, Aubrey L. Miller, Kelly M. Kreitzburg, Leona N. Council, Tracy L. Gamblin, John D. Christein, Marty J. Heslin, J. Pablo Arnoletti, Joseph H. Richardson, D Chen, C. Alexandra Hanna, S L Cramer, Eddy S. Yang, Jun Qi, James E. Bradner, Karina J. Yoon

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Phthalimide conjugation as a strategy for in vivo target protein degradation Autor Georg E. Winter, Dennis L. Buckley, Joshiawa Paulk, Justin M. Roberts, Amanda Souza, Sirano Dhe‐Paganon, James E. Bradner

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Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors Autor Gopalakrishnan Ramakrishnan, Hittu Matta, Bhairavi Tolani, Timothy J. Triche, Preet M. Chaudhary

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The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation Autor Chiara Pastori, Philipp Kapranov, Clara Penas, Veronica J. Peschansky, Claude‐Henry Volmar, Jann N. Sarkaria, Amadé Bregy, Ricardo J. Komotar, Georges St. Laurent, Nagi G. Ayad, Claes Wahlestedt

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BET bromodomain inhibition suppresses transcriptional responses to cytokine‐Jak‐STAT signaling in a gene‐specific manner in human monocytes Autor Chun Hin Chan, Celestia Fang, Yu Qiao, Anna Yarilina, Rab K. Prinjha, Lionel B. Ivashkiv

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Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration Autor Sungjin Ko, Tae‐Young Choi, Jacquelyn O. Russell, Juhoon So, Satdarshan P. Monga, Donghun Shin

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BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries Autor Bowen Wang, Mengxue Zhang, Toshio Takayama, Xudong Shi, Drew Alan Roenneburg, K. Craig Kent, Lian‐Wang Guo

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Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism Autor Huasong Lu, Yuhua Xue, Guoying Karen Yu, Carolina Arias, Julie Lin, Susan Fong, Michel Faure, Ben Weisburd, Xiao‐Dan Ji, Alexandre Mercier, James Sutton, Kunxin Luo, Zhenhai Gao, Qiang Zhou

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Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery Autor Leilei Fu, Mao Tian, Xiang Li, Jing Li, Jian Huang, Liang Ouyang, Yonghui Zhang, Bo Liu

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Targeted Recruitment of the Sin3-Rpd3 Histone Deacetylase Complex Generates a Highly Localized Domain of Repressed Chromatin In Vivo Autor David Kadosh, Kevin Struhl

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An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reacti... Autor Gilles Darcis, Anna Kula, Sophie Bouchat, Koh Fujinaga, Francis Corazza, Amina Aït-Ammar, Nadège Delacourt, Adeline Mélard, Kabamba Kabeya, Caroline Vanhulle, Benoît Van Driessche, Jean-Stéphane Gatot, Thomas Cherrier, Luiz F. Pianowski, Lúcio Gama, Christian Schwartz, Jorge Vila, Arsène Burny, Nathan Clumeck, Michel Moutschen, Stéphane De Wit, B. Matija Peterlin, Christine Rouzioux, Olivier Rohr, Carine Van Lint

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Genetic Analysis of brahma: The Drosophila Homolog of the Yeast Chromatin Remodeling Factor SWI2/SNF2 Autor Lisa Elfring, Carla Daniel, Ophelia Papoulas, Renate Deuring, Melinda Sarte, Sarah Moseley, Shelley J Beek, W. Ross Waldrip, Gary Daubresse, Angela H. DePace, James A. Kennison, John W. Tamkun

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Bromodomain-dependent stage-specific male genome programming by Brdt Autor Jonathan Gaucher, Fayçal Boussouar, Emilie Montellier, Sandrine Curtet, Thierry Buchou, Sarah Bertrand, Patrick Héry, Sylvie Jounier, Arnaud Depaux, Anne-Laure Vitte, Philippe Guardiola, Karin Pernet, Alexandra Debernardi, Fabrice Lopez, Hélène Holota, Jean Imbert, Debra J. Wolgemuth, Matthieu Gérard, Sophie Rousseaux, Saadi Khochbin

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