eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling

eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling

Despite encouraging preclinical data, therapies to reduce ARDS mortality remains a globally unmet need, including during the COVID-19 pandemic. We previously identified extracellular nicotinamide phosphoribosyltransferase (eNAMPT) as a novel damage-associated molecular pattern protein (DAMP) via TLR...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bermudez, Tadeo, Sammani, Saad, Song, Jin H., Hernon, Vivian Reyes, Kempf, Carrie L., Garcia, Alexander N., Burt, Jessica, Hufford, Matthew, Camp, Sara M., Cress, Anne E., Desai, Ankit A., Natarajan, Viswanathan, Jacobson, Jeffrey R., Dudek, Steven M., Cancio, Leopoldo C., Alvarez, Julie, Rafikov, Ruslan, Li, Yansong, Zhang, Donna D., Casanova, Nancy G., Bime, Christian, Garcia, Joe G. N.
स्वरूप: मूलपाठ
भाषा:अंग्रेज़ी
प्रकाशित: Nature Publishing Group UK 2022
विषय:
Article
ऑनलाइन पहुंच:https://pmc.ncbi.nlm.nih.gov/articles/PMC8758770/
https://pubmed.ncbi.nlm.nih.gov/35027578
http://dx.doi.org/10.1038/s41598-021-04444-9
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इंटरनेट

https://pmc.ncbi.nlm.nih.gov/articles/PMC8758770/
https://pubmed.ncbi.nlm.nih.gov/35027578
http://dx.doi.org/10.1038/s41598-021-04444-9

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