Sclerostin antibody improves phosphate metabolism hormones, bone formation rates, and bone mass in adult Hyp mice

Sclerostin antibody improves phosphate metabolism hormones, bone formation rates, and bone mass in adult Hyp mice

X-linked hypophosphatemia (XLH) is caused by a loss-of-function mutation in the phosphate regulating gene with homology to endopeptidase located on the X chromosome (PHEX). Loss of functional PHEX results in elevated fibroblast growth factor 23 (FGF23), impaired phosphate reabsorption, and inhibited...

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Bibliografische gegevens
Hoofdauteurs: Carpenter, Kelsey A., Davison, Reid, Shakthivel, Shruti, Anderson, Kyle D., Ko, Frank C., Ross, Ryan D.
Formaat: Text
Taal:Engels
Gepubliceerd in: 2021
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Article
Online toegang:https://pmc.ncbi.nlm.nih.gov/articles/PMC8671249/
https://pubmed.ncbi.nlm.nih.gov/34537437
http://dx.doi.org/10.1016/j.bone.2021.116201
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Internet

https://pmc.ncbi.nlm.nih.gov/articles/PMC8671249/
https://pubmed.ncbi.nlm.nih.gov/34537437
http://dx.doi.org/10.1016/j.bone.2021.116201

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