POLRMT as a Novel Susceptibility Gene for Cardiotoxicity in Epirubicin Treatment of Breast Cancer Patients

POLRMT as a Novel Susceptibility Gene for Cardiotoxicity in Epirubicin Treatment of Breast Cancer Patients

Anthracyclines are among the most used chemotherapeutic agents in breast cancer (BC). However their use is hampered by anthracycline-induced cardiotoxicity (AIC). The currently known clinical and genetic risk factors do not fully explain the observed inter-individual variability and only have a limi...

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Main Authors: Velasco-Ruiz, Alejandro, Nuñez-Torres, Rocio, Pita, Guillermo, Wildiers, Hans, Lambrechts, Diether, Hatse, Sigrid, Delombaerde, Danielle, Van Brussel, Thomas, Alonso, M. Rosario, Alvarez, Nuria, Herraez, Belen, Vulsteke, Christof, Zamora, Pilar, Lopez-Fernandez, Teresa, Gonzalez-Neira, Anna
Format: Text
Language:English
Published: MDPI 2021
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC8622627/
https://pubmed.ncbi.nlm.nih.gov/34834357
http://dx.doi.org/10.3390/pharmaceutics13111942
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https://pmc.ncbi.nlm.nih.gov/articles/PMC8622627/
https://pubmed.ncbi.nlm.nih.gov/34834357
http://dx.doi.org/10.3390/pharmaceutics13111942

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