Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma

BACKGROUND: Tobacco is the main risk factor for developing lung cancer. Yet, some heavy smokers do not develop lung cancer at advanced ages while others develop it at young ages. Here, we assess for the first time the genetic background of these clinically relevant extreme phenotypes using whole exo...

Full description

Saved in:
Bibliographic Details
Main Authors: Patiño-García, Ana, Guruceaga, Elizabeth, Segura, Victor, Sánchez Bayona, Rodrigo, Andueza, Maria Pilar, Tamayo Uria, Ibon, Serrano, Guillermo, Fusco, Juan Pablo, Pajares, María José, Gurpide, Alfonso, Ocón, Marimar, Sanmamed, Miguel F., Rodriguez Ruiz, Maria, Melero, Ignacio, Lozano, Maria Dolores, de Andrea, Carlos, Pita, Guillermo, Gonzalez-Neira, Anna, Gonzalez, Alvaro, Zulueta, Javier J., Montuenga, Luis M., Pio, Ruben, Perez-Gracia, Jose Luis
Format: Text
Language:English
Published: AME Publishing Company 2021
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC8044482/
https://pubmed.ncbi.nlm.nih.gov/33889513
http://dx.doi.org/10.21037/tlcr-20-1197
Tags: Add Tag
No Tags, Be the first to tag this record!