Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

Inhibition of platelet reactivity is a common therapeutic strategy in secondary prevention of cardiovascular disease. Genetic and environmental factors influence inter-individual variation in platelet reactivity. Identifying genes that contribute to platelet reactivity can reveal new biological mech...

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Hoofdauteurs: Eicher, John D., Chen, Ming-Huei, Pitsillides, Achilleas N., Lin, Honghuang, Veeraraghavan, Narayanan, Brody, Jennifer A., Metcalf, Ginger A., Muzny, Donna M., Gibbs, Richard A., Becker, Diane M., Becker, Lewis C., Faraday, Nauder, Mathias, Rasika A., Yanek, Lisa R., Boerwinkle, Eric, Cupples, L. Adrienne, Johnson, Andrew D.
Formaat: Text
Taal:Engels
Gepubliceerd in: 2017
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Article
Online toegang:https://pmc.ncbi.nlm.nih.gov/articles/PMC7472427/
https://pubmed.ncbi.nlm.nih.gov/28300864
http://dx.doi.org/10.1160/TH16-09-0677
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Internet

https://pmc.ncbi.nlm.nih.gov/articles/PMC7472427/
https://pubmed.ncbi.nlm.nih.gov/28300864
http://dx.doi.org/10.1160/TH16-09-0677

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