Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats

Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of complete unloading. More recently, the effects of partial unloading on the musculoskeletal system have been interrogated in mice and rats, r...

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Bibliographic Details
Main Authors: Ko, Frank C., Mortreux, Marie, Riveros, Daniela, Nagy, Janice A., Rutkove, Seward B., Bouxsein, Mary L.
Format: Text
Language:English
Published: Nature Publishing Group UK 2020
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC7235020/
https://pubmed.ncbi.nlm.nih.gov/32435691
http://dx.doi.org/10.1038/s41526-020-0105-0
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