Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis

Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis

Anterior cruciate ligament (ACL) transection surgery in the minipig induces post-traumatic osteoarthritis (PTOA) in a pattern similar to that seen in human patients after ACL injury. Prior studies have reported the presence of cartilage matrix-degrading proteases, such as Matrix metalloproteinase-1...

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Main Authors: Ayturk, Ugur M., Sieker, Jakob T., Haslauer, Carla M., Proffen, Benedikt L., Weissenberger, Manuela H., Warman, Matthew L., Fleming, Braden C., Murray, Martha M.
Format: Text
Language:English
Published: Public Library of Science 2020
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Research Article
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC7046188/
https://pubmed.ncbi.nlm.nih.gov/32107493
http://dx.doi.org/10.1371/journal.pone.0229449
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https://pmc.ncbi.nlm.nih.gov/articles/PMC7046188/
https://pubmed.ncbi.nlm.nih.gov/32107493
http://dx.doi.org/10.1371/journal.pone.0229449

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