Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts

Whole-genome sequencing (WGS) can improve assessment of low-frequency and rare variants, particularly in non-European populations that have been underrepresented in existing genomic studies. The genetic determinants of C-reactive protein (CRP), a biomarker of chronic inflammation, have been extensiv...

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Detaylı Bibliyografya
Asıl Yazarlar: Raffield, Laura M., Iyengar, Apoorva K., Wang, Biqi, Gaynor, Sheila M., Spracklen, Cassandra N., Zhong, Xue, Kowalski, Madeline H., Salimi, Shabnam, Polfus, Linda M., Benjamin, Emelia J., Bis, Joshua C., Bowler, Russell, Cade, Brian E., Choi, Won Jung, Comellas, Alejandro P., Correa, Adolfo, Cruz, Pedro, Doddapaneni, Harsha, Durda, Peter, Gogarten, Stephanie M., Jain, Deepti, Kim, Ryan W., Kral, Brian G., Lange, Leslie A., Larson, Martin G., Laurie, Cecelia, Lee, Jiwon, Lee, Seonwook, Lewis, Joshua P., Metcalf, Ginger A., Mitchell, Braxton D., Momin, Zeineen, Muzny, Donna M., Pankratz, Nathan, Park, Cheol Joo, Rich, Stephen S., Rotter, Jerome I., Ryan, Kathleen, Seo, Daekwan, Tracy, Russell P., Viaud-Martinez, Karine A., Yanek, Lisa R., Zhao, Lue Ping, Lin, Xihong, Li, Bingshan, Li, Yun, Dupuis, Josée, Reiner, Alexander P., Mohlke, Karen L., Auer, Paul L.
Materyal Türü: Metin
Dil:İngilizce
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Online Erişim:https://pmc.ncbi.nlm.nih.gov/articles/PMC7042494/
https://pubmed.ncbi.nlm.nih.gov/31883642
http://dx.doi.org/10.1016/j.ajhg.2019.12.002
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