Systems and Synthetic microRNA Biology: From Biogenesis to Disease Pathogenesis

MicroRNAs (miRNAs) are approximately 22-nucleotide-long, small non-coding RNAs that post-transcriptionally regulate gene expression. The biogenesis of miRNAs involves multiple steps, including the transcription of primary miRNAs (pri-miRNAs), nuclear Drosha-mediated processing, cytoplasmic Dicer-med...

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Bibliographic Details
Main Authors: Matsuyama, Hironori, Suzuki, Hiroshi I.
Format: Text
Language:English
Published: MDPI 2019
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC6981965/
https://pubmed.ncbi.nlm.nih.gov/31878193
http://dx.doi.org/10.3390/ijms21010132
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