The Unmixing Problem: A Guide to Applying Single-Cell RNA Sequencing to Bone: APPLYING SINGLE-CELL RNA SEQUENCING TO BONE

Bone is composed of a complex mixture of many dynamic cell types. Flow cytometry and in vivo lineage tracing have offered early progress toward deconvoluting this heterogeneous mixture of cells into functionally well-defined populations suitable for further studies. Single-cell sequencing is poised...

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Bibliographic Details
Main Authors: Greenblatt, Matthew B, Ono, Noriaki, Ayturk, Ugur M, Debnath, Shawon, Lalani, Sarfaraz
Format: Text
Language:English
Published: 2019
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC6658136/
https://pubmed.ncbi.nlm.nih.gov/31336008
http://dx.doi.org/10.1002/jbmr.3802
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