PIPKIγ and talin couple phosphoinositide and adhesion signaling to control the epithelial to mesenchymal transition

Epithelial cells acquire migratory/invasive and stemness traits upon conversion to the mesenchymal phenotype. The expression of E-cadherin is a key to this transition; yet precise understanding of the pathways involved in integrating E-cadherin loss to the gain of mesenchymal traits remains poorly u...

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Bibliographic Details
Main Authors: Thapa, N, Tan, X, Choi, S, Wise, T, Anderson, RA
Format: Text
Language:English
Published: 2016
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC6344042/
https://pubmed.ncbi.nlm.nih.gov/27452517
http://dx.doi.org/10.1038/onc.2016.267
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