Germline mutations and somatic inactivation of TRIM28 in Wilms tumour

Germline mutations and somatic inactivation of TRIM28 in Wilms tumour

Wilms tumour is a childhood tumour that arises as a consequence of somatic and rare germline mutations, the characterisation of which has refined our understanding of nephrogenesis and carcinogenesis. Here we report that germline loss of function mutations in TRIM28 predispose children to Wilms tumo...

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Main Authors: Halliday, Benjamin J., Fukuzawa, Ryuji, Markie, David M., Grundy, Richard G., Ludgate, Jackie L., Black, Michael A., Skeen, Jane E., Weeks, Robert J., Catchpoole, Daniel R., Roberts, Aedan G. K., Reeve, Anthony E., Morison, Ian M.
Format: Text
Language:English
Published: Public Library of Science 2018
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Research Article
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC6005459/
https://pubmed.ncbi.nlm.nih.gov/29912901
http://dx.doi.org/10.1371/journal.pgen.1007399
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https://pmc.ncbi.nlm.nih.gov/articles/PMC6005459/
https://pubmed.ncbi.nlm.nih.gov/29912901
http://dx.doi.org/10.1371/journal.pgen.1007399

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