Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics

RNA interference (RNAi) is a major powerful platform for gene perturbations, but is restricted by off-target mechanisms. Communication between RNAs, small RNAs, and RNA-binding proteins (RBPs) is a pervasive feature of cellular RNA networks. We present a new crosstalk scenario, designated as “crosst...

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Bibliographic Details
Main Authors: Suzuki, Hiroshi I., Spengler, Ryan M., Grigelioniene, Giedre, Kobayashi, Tatsuya, Sharp, Phillip A.
Format: Text
Language:English
Published: 2018
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC5934319/
https://pubmed.ncbi.nlm.nih.gov/29662165
http://dx.doi.org/10.1038/s41588-018-0104-1
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