Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models
Feingold syndrome is a skeletal dysplasia caused by loss-of-function mutations of either MYCN (type 1) or MIR17HG that encodes miR-17-92 microRNAs (type 2). Since miR-17-92 expression is transcriptionally regulated by MYC transcription factors, it has been postulated that Feingold syndrome type 1 an...
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| Main Authors: | , , , , , |
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| Format: | Text |
| Language: | English |
| Published: |
Nature Publishing Group UK
2018
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| Subjects: | |
| Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC5893605/ https://pubmed.ncbi.nlm.nih.gov/29636449 http://dx.doi.org/10.1038/s41467-018-03788-7 |
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